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Amyloid β peptide (Aβ42) assemblies are considered central to the development of Alzheimer's disease, but the mechanism of this toxicity remains unresolved. We screened protein microarrays with on-pathway oligomeric Aβ42 to identify candidate proteins interacting with toxic Aβ42 species. Samples prepared from Alexa546-Aβ42 and Aβ42 monomers at 1:5 molar ratio were incubated with the array during a

The article describes a survey of the societal services in Sweden that are available after a spinal cord injury. These services are allocated to allow independence and financial compensation. I have investigated the kinds of services that are available. I have also interviewed 34 of a total incidence population of 48 people, to find out which services were applied for, and to describe the levels o

ABSTRACT: BACKGROUND: Urothelial carcinoma (UC) is characterized by nonrandom chromosomal aberrations, varying from one or a few changes in early-stage and low-grade tumors, to highly rearranged karyotypes in muscle-invasive lesions. Recent array-CGH analyses have shed further light on the genomic changes underlying the neoplastic development of UC, and have facilitated the molecular delineation a

Popular discussions over Jesus as the Son of God are mostly predetermined by the Creed or by a ”Christology from above”. Against this background the question on when Jesus began to be called ”Son of God” might be answered in a reductionist way, giving priority to the oldest and least developed forms of Christology. As a matter of fact, however, historical-critical exegesis has shown that titles an

This paper offers a positive identification of Sahl ibn Bishr’s Kitāb al-ʾaḥkām ʿalā ʾn-niṣba al-falakiyya as the Arabic source text for what is perhaps the most characteristic feature of the medieval Perso-Indian style of astrology known as tājika: the sixteen yogas or types of planetary configurations. The dependence of two late sixteenth-century tājika works in Sanskrit – Nīlakaṇṭha’s Tājikanīl

We studied medical records for out-patient treatments with intravenous immunoglobulins during 2005 at the neurological clinics in Skåne and evaluated patient opinions using a questionnaire. Of 64 patients, 10 had started their therapy during the period, and 14 had it terminated. In five medical records doctor had defined and documented a therapy objective at the start of therapy and in six cases t

BACKGROUND: Neutralizing antibody assessments play a central role in human immunodeficiency virus type-1 (HIV-1) vaccine development but it is unclear which assay, or combination of assays, will provide reliable measures of correlates of protection. To address this, an international collaboration (NeutNet) involving 18 independent participants was organized to compare different assays. METHODS: Ea

The quaternary system comprising sodium dodecyl sulfate/water/pentanol/dodecane has been studied at high oil content and at two different water-to-surfactant ratios. Of particular interest is a highly flow birefringent, isotropic fluid phase, which occupies an island in the pseudo-ternary phase diagrams between the L₂ phase and the L₃ phase and which is in close proximity to

We use a genetic algorithm to theoretically optimize several properties of extreme ultraviolet (XUV) radiation, generated as high-order harmonics in xenon and argon. We maximize the harmonic pulse energy, minimize the pulse duration or optimize the temporal coherence by varying at the same time two or three parameters that are easily accessible in experiments, related to the characteristics of the

The actual place for the murder cases is the small town Ystad in the south of Sweden. This is the scene for the films and books about the police inspector Kurt Wallander, created by the Swedish author and playwright Henning Mankell. Ystad is also the place where a new regional centre for film production is situated, and the Wallander movies play an important part in the economic conditions of this