BACKGROUND AND PURPOSE: Genome-wide association (GWA) studies have identified a few risk loci for ischaemic stroke, but these variants explain only a small part of the genetic contribution to the disease. Coding variants associated with amino acid substitutions or premature termination of protein synthesis could have a large effect on disease risk. We performed an exome array analysis for ischaemi

OBJECTIVE: To investigate the influence of common and low-frequency genetic variants on the risk of ischemic stroke (all IS) and etiologic stroke subtypes.METHODS: We meta-analyzed 12 individual genome-wide association studies comprising 10,307 cases and 19,326 controls imputed to the 1000 Genomes (1 KG) phase I reference panel. We selected variants showing the highest degree of association (p < 1

BACKGROUND: As many as 88% of heart transplant recipients (HTRs) suffer from psychological distress. Both psychosocial factors and physical health are associated with increased psychological distress. However, the causes and impacts of psychological distress are unclear. HTRs strive for a sense of control over their health and daily lives in order to improve their psychological well-being. Perceiv

AIMS: The aims of this study were two-fold: to develop the concept analysis by Allvin et al. from lung recipients' perspective of their post-transplant recovery process and to identify the recovery trajectories including critical junctions in the post-transplant recovery process after lung transplantation.BACKGROUND: Lung transplantation is an established treatment for patients with end-stage lung

Several studies have shown associations between shorter telomere length in blood and weakened immune function, susceptibility to infections, and increased risk of morbidity and mortality. Recently, we have shown that malaria accelerates telomere attrition in blood cells and shortens lifespan in birds. However, the impact of infections on telomere attrition in different body tissues within an indiv

From 1950 until 1975 approximately 1.3 million apartments were built in Sweden. Now, a considerable part of these are in need of renovation. This paper is part of an evaluation of a new DCV system developed especially for the renovation of these houses. The DCV automatically regulates the air change rate for each dwelling based on measurements of the indoor air. One of the measured parameters is t

To meet EU energy and climate targets, energy efficiency of the existing building stock must be drastically improved. Within IEA EBC Annex 56 one of the best practice examples of energy renovations is a group of multi-family buildings in Sweden, recently thoroughly renovated. For this group of buildings the residents' perception of renovations and appraisal of implemented measures were captured by

The present study is divided in two differentiable but conceptually interrelated sections. Within the first section (Chapters I, II, and III), the focus is on the assessment of the argumentative logic behind the multiculturalist proposal for equally divided societies, among equally positioned ethno-cultural groups. A critical and analytical review of the multiculturalist argumentative construction

Background: Overuse injuries in sports seem to be 1.5 to 2.5 times more common than traumatic injuries in the lower extremity (LE) in children and adolescents. Floorball is the most popular indoor sport in Sweden and is associated with many potential risks of injuries. However, to our knowledge, no previous studies have examined the appearance of injury in young floorball players. Objective: The a

Dielectric elastomers offer clear advantages over more traditional and conventional materials when soft, lightweight, noiseless actuator applications with large deformations are considered. However, the viscous time-dependent behaviour associated with most elastomers limit the number of possible applications. For this purpose, the possibility of controlling the viscous response by regulating the a

Bellicist theories of comparative development predict increases in taxation as the result of military rivalries. Others claim that this causal relationship is contingent on particular geographical, institutional, and historical conditions. In this paper, we explore the conditional effects of military rivalries on taxation during the 19th and 20th centuries using time-series cross-section models. W

Teachers have high occupational voice demands. The voice load of teachers is both environmental and individual. Little is known about the teachers' own view of the contribution from the environment and about the teachers' voice use at their work-place. Aim: The purpose was to investigate the voice use and prevalence of voice problems in teachers and to explore their ratings of vocally loading aspe

This authoritative Handbook examines the current state and the future needs of international law in addressing the key activities that pose threats to the marine environment. Its chapters explore the legal framework for protection of the marine environment, pollution of the marine environment, seabed activities and the marine environment, protection of marine biodiversity, regional approaches to t

Stereo rendering for 3D displays and for virtual reality headsets provide several visual cues, including convergence angle and high- light disparity. The human visual system interprets these cues to estimate surface properties of the displayed environment. Naïve stereo rendering effectively doubles the computational burden of image synthesis, and thus it is desirable to reuse as many computa- tion