Streptococcus pyogenes, the most significant streptococcal species in clinical medicine, expresses surface proteins with affinity for several human plasma proteins. Here we report that kininogens, the precursors to the vasoactive kinins, bind to the surface of S. pyogenes. M protein, a surface molecule and a major virulence factor-in these bacteria, occurs in > 80 different serotypes. Among 49 str

A disaccharide scaffold based on galabiose (Gal1–4Gal) was synthesized. Four different acceptors were evaluated in the -galactosylation and a relationship between the nucleophilicity, yield, and /-selectivity was found. The scaffold contains two orthogonal derivatisation sites, i.e. at O-2′ and the anomeric position, and as proof of concept, one derivatised galabioside was synthesized. Compounds b

The evolution of carbon-oxygen-related defects upon isochronal annealing (75-325 degrees C in 25 degrees C steps for 30 min at each temperature) in electron irradiated Si crystals has been studied by means of local vibrational mode (LVM) spectroscopy. A complicated annealing behaviour of the LVMs related to the C4 (ICiOi) defect has been observed. At about 200 degrees C the bands at 940 and 1024 c

Polymerase chain reaction (PCR) is recognized as a rapid, sensitive, and specific molecular diagnostic tool for the analysis of nucleic acids. However, the sensitivity and kinetics of diagnostic PCR may be dramatically reduced when applied directly to biological samples, such as blood and feces, owing to PCR-inhibitory components. As a result, pre-PCR processing procedures have been developed to r

Developing guidelines for quality assurance in the management of head injury requires knowledge concerning present management practice. We studied management of minor head injury (MHI) using a cross-sectional mail survey of 76 Swedish hospitals. In 96% of the hospitals, initial patient evaluation, frequently performed by inexperienced physicians, entails neurological assessment according to the Sw

The complete mitochondrial genome of the endangered Banded Hare wallaby (Lagostrophus fasciatus) was sequenced and used for phylogenetic analysis. The data set consisted of 10 377 nucleotides (3459 amino acids) from three kangaroo species. The phylogenetic analyses strongly supported the hypothesis that the Banded Hare wallaby is the sister-group of the wallaroo (subfamily Macropodidae). In additi

In the transition from curative treatment to palliative care of a general end-of-life patient population, the internal communication of the acute care staff seems to be less than optimal. The communication had reference to the dialogue within the staff both before and after the decision to concentrate on palliative care, and possible transfer of the patient. This survey of Swedish nurses and physi

The very large multiplicity of charged particles encountered in lead on lead collisions in the WA98 experiment at the CERN SPS provided new experimental challenges. Tracking detectors read out with high granularity were developed to achieve accurate position information in two dimensions, with the aim of reconstructing tracks with a minimum of combinatorial difficulties. A tracking system based on

A poly(Toluidine Blue O) (poly-TBO) modified electrode was successfully prepared by repeated sweeping the applied potential from -0.6 to + 0.8 V (vs. SCE) on a glassy carbon electrode (GCE) in borate buffer solution at pH 9.1 containing 0.1 M NaNO3 and 0.4 mM Toluidine Blue 0 (TBO). The poly-TBO modified GCE shows electrocatalytic activity toward NADH oxidation in phosphate buffer solution at pH 7

Relative autonomy refers to the space that teachers have or can create to make choices regarding the curriculum of schooling. In order to transform conflicts and to cope with the tensions that arise in time of change, teachers are urged to make constructive use of their relative autonomy. In this paper some of the conflicts and tensions that exist today are discussed in the context of the Swedish

Den elektroniska revolutionen har satt gränsen mellan original och kopia i fråga. Musikindustrin har därför drabbats av ett akut problem, för vem har rätt till vad när upphovsmannaskapet är oklart?

Mo oxide films were prepared by dual-target reactive DC magnetron sputtering under conditions leading to films that were blue in as-deposited state. The deposition rate for this “blue” Mo oxide was as high as 1.5 nm/s, to be compared to ∼0.85 and ∼0.1 nm/s for highly transparent Mo oxide films made with dual-target and single-target sputtering, respectively. Good electrochromic properties of the “

I denna skrift visas ett antal beräkningsexempel på hur fuktinnehållet i en gotländsk sandsten kan variera med varierande randvillkor. Teorin och numerisk metod för beräkningarna beskrivs i detalj.

The DELPHI experiment at the LEP e (+) e(-) collider collected almost 700 pb(-1) at centre-of-mass energies above the Z(0) mass pole and up to 208 GeV. Those data were used to search for SUSY in the Anomaly Mediated SUSY Breaking (AMSB) scenario with a flavour independent common sfermion mass parameter. The searches covered several possible signatures experimentally accessible at LEP, with either