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Populärvetenskaplig sammanfattning Genen MYCN kodar för N-Myc, ett protein som fungerar som transkriptionsfaktor, det vill säga det kontrollerar vilka gener som transkriberas aktivt från DNA till RNA. Många neuroendokrina tumörer, speciellt neuroblastoma, uppvisar ofta onormalt höga nivåer av N-Myc, och eftersom N-Myc startar transkriptionen av många gener som är viktiga för cellens delning, tillvThe gene MYCN encodes a transcription factor with a fundamental role in many neuroendocrine tumors, especially neuroblastoma. The gene and protein are very similar to the closely related c-Myc protein, except for the 3´untranslated region (3´UTR), suggesting that it may be an important factor in determining their very different expression pattern at the post-transcriptional level. MicroRNA (miRNA)

Electrocardiograms have, since the beginning of the 1900s, been used as a noninvasive diagnostic method to reflect underlying heart conditions by measuring the electrical activity of the heart. Novosense AB has developed a new technology for completely wireless recording of ECG. Their goal is to replace the stationary patient monitors and telemetry systems. Unlike today's technology, where a c

Prostate cancer is the most common form of cancer amongst males in the western world. Today’s diagnostic methods for prostate cancer that rely on PSA measurement are not satisfying. The level of prostate specific antigen (PSA) is determined in a blood test. Of the men with elevated PSA levels only 25 % have prostate cancer. This thesis aims to develop a proof of concept for a miniaturized multiple

The wave of protests in the Middle East, that started in Tunisia at the end of 2010 and brought about President Ben Ali’s removal from power took the world by storm. The aim of this thesis is to examine the role of the coercive apparatus in the outcome of the uprising, by examining the factors that affected its will and capacity to repress popular mobilisation. The four factors outlined as affecti

Kulturmejeriet i Lund är en unik inrättning som underhållit kulturlivet i Lund i flera decennier. Denna studie söker insikt i vilka krafter som drivit utvecklingen av en välbesökt och väl förankrad förening med en bred och trogen publik. Problemformuleringen lyder: Vilka drivkrafter ligger bakom framgången med kulturhuset Mejeriet? Resultat: Tre tydliga drivkrafter har definierats: Kamp – Vilket

Under den svenska lagstiftningsprocessen skapas material som brukar benämnas lagförarbeten. Några av de viktigare är kommittébetänkanden, propositioner och utskottsbetänkanden. Sedan lång tid tillbaka använder sig domstolarna av sådana förarbeten när det anses att lagtexten inte ger tillräcklig ledning. I vissa fall har förarbetena en helt avgörande betydelse för domstolarnas avgöranden. FörarbetsPreparatory works such as, e.g. investigative reports, propositions, and committee reports, are created during the Swedish legislative process. The courts have, by tradition dating back many years, used these preparatory works as a source of law when interpretating acts of legislation. In some cases, preparatory works are the determinants for the courts’ rulings. The use of preparatory works has a

The tendency to buy goods and especially services is increasing in our society. This has strongly affected the retail markets in Finland during the last decade. The consumers are affected by the dynamic society, which have set new challenges for consumption. Shopping centres are similar to each other and therefore the experience can be a determining factor when choosing the shopping centre. A shop

Many problems in computer vision can be formulated as optimization problems that can be solved using minimum cuts in flow networks. However, these applications can be demanding, with the memory bandwidth being the main bottleneck on the performance. This thesis introduces an efficient solver that reduces the memory requirements while improving the speed. The code is freely available on-line.

Induktorer är en central del i Tetra Paks förpackningsmaskin A3/Flex eftersom induktorerna levererar energin som förseglar varje förpackning. Fel, till exempel att en kork hamnar snett, orsakar efterföljande felaktiga förseglingar och i värsta fall driftstopp. För att undvika detta pågår ständigt arbete med att förbättra och utveckla maskinerna och undvika problem för kunder till Tetra Pak. Detta

Korruption är ett begrepp som inte har någon klar definition. Det är många vetenskaper som diskuterar korruption, dock görs detta med delvis olika synvinklar. Denna framställning visar att det finns många olika perspektiv att anlägga på korruptionsproblematiken, perspektiv som dessutom leder till olika slutsatser om problematikens orsaker och verkan. Fler tvärvetenskapliga perspektiv behövs, för aCorruption is a term that has no clear definition. There are many disciplines that discuss corruption, however, this is done with somewhat different perspectives. This essay shows multiple perspectives on corruption issues, perspectives which also lead to different conclusions about the causes and effects of corruption. More interdisciplinary perspectives are needed to be able to work against corr

During the bachelor project I developed a flying vehicle for the antarctic environment and the Rotary Vehicle model number 101 was the transportation solution this project resulted in. The goal was to develop a safer and environmentally friendlier vehicle then the helicopter, the only existing vertical landing and take off vehicle operating today on Antarctica. Sir

This project is cooperated with IKEA, under their “Future Home ” project. “Resource sharing“ is one of the subparts. The main idea is to encourage people to share resources and time to lower the cost and to reduce carbon footprint. The focus is to motivate residents to have more social interactions with their neighbours, which is the beginning of sharing. The strategy is to learn from traditional

Projektets syfte har varit att försöka ta fram en anpassad försäljningsvagn för tåg. Vagnarna som används idag ombord är inte framtagna för att användas på tåg, vilket bland annat har lett till belastningsskador hos personalen. Anledningen till varför inte några nya vagnar har tagits fram framkom under projektets gång. Det beror på att det är stora bolag som anlitar mindre bolag som sköter allt kr

DISA is an international company in the foundry industry. They build and develop foundry machinery to foundry companies around the world. They also help its customers to provide service on the machines. Today, their customers have no effective system for reporting errors, work and documentation of service. This problem led to the development of a service system that facilitates and streamlines the

Att bygga betongbroar med inslag av prefabricering i Sverige är idag relativt ovanligt. Man vill gärna undvika obeprövade metoder för att hålla riskerna i projekten så låga som möjligt. Samtidigt har det prefabricerade byggandets potential att öka effektiviteten och därav också lönsamheten lett till att en del prefabricerade broar byggts. På senare tid har Trafikverket, den enskilt största bes

Initially, this paper presents an overview of the existing methods used for the identification of vortices in fluids, attempting to point out their different strengths and weaknesses. In addition, a new method is proposed to identify vortices directly from velocity field information. It defines a point inside a vortex as a point around which there is rotation. By looking at the velocity directions

The aim of this study is to investigate whether a virtual environment can be used as a complement to conventional experiments regarding human behaviour in fires and evacuations. Initially, a study of previous research in the field of human behaviour in fires and Virtual Reality was performed. To be able to do a validation of the use of Virtual Reality in relation to conventional experiments, a pre