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Rapid morphological changes and loss of collagen following experimental acute colonic obstruction

Anastomosis of an acutely obstructed colon is associated with an increased risk of dehiscence. In experimental models, acute obstruction decreases collagen in the colonic wall, but the time course and propagation along the colon of the biochemical changes are unknown. Furthermore, there is a paucity of information on the correlation between these biochemical changes and histological features. Fort

The Internationalization of Economic History - Perspectives from the African Frontier

In an interesting and thought-provoking paper recently published by the Economic History of Developing Regions, Johan Fourie and Leigh Gardner ask why relatively few papers from developing countries have been published in top-ranked economic history journals. They provide a number of tentative answers of which differences in academic traditions between regions seem to be an important one. In this

QA procedures needed for advanced RT techniques and its impact on treatment outcome

The radiotherapy process is reviewed briefly and potential risks or pitfalls are identified. The focus is on modern advanced modalities in radiation therapy such as IMRT, VMAT, gating and tracking and also for the unknown to come. Existing methods, or quality controls (QC), or with better word barriers, are introduced at important steps of process with the purpose of prohibiting errors to continue

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Abstract in Romanian ntemeiată la 1348, Universitatea Carolină din Praga se numără printre cele mai vechi instituţii de învăţământ superior din lume. Studiul limbii române beneficiază aici de o bogată tradiţie, acesta fiind introdus la catedra de limbi romanice a Universităţii încă din anul 1882 de către profesorul ceh de filologie Jan Urban Jarník (1848-1923). Este notabil şi faptul că UniversitaFounded in 1348, Charles University in Prague is among the oldest academic institutions in the world. Teaching the Romanian language has a longstanding tradition as well: it was established by the Czech philologist Jan Urban Jarník (1848-1923) within the Romance Department in 1882. Thus Charles University in Prague became the fifth university outside Romania that began teaching Romanian language (

Search for anomalous production of prompt like-sign lepton pairs at root s=7 TeV with the ATLAS detector

An inclusive search for anomalous production of two prompt, isolated leptons with the same electric charge is presented. The search is performed in a data sample corresponding to 4.7 fb(-1) of integrated luminosity collected in 2011 at root s = 7TeV with the ATLAS detector at the LHC. Pairs of leptons (e(+/-)e(+/-), e(+/-)mu(+/-), and mu(+/-)mu(+/-)) with large transverse momentum are selected, an

A new volume scanner

Optical imaging through complex biological media remains a very challenging task due to the extremely high scattering experienced. A new design scanner is proposed and modelled which images scatter spatio-temporally. Modeling confirms the performance of the design. The inversion algorithm to reconstruct the scattering object remains as future work.

Validity of histology for the diagnosis of paediatric coeliac disease: a Swedish multicentre study.

Objective Histological evaluation of intestinal biopsies for the diagnosis of coeliac disease can be challenging and compatible with risk of misdiagnosis. The aim was to evaluate the agreement of pathological diagnosis for coeliac disease in children investigated at four major paediatric university hospitals in Sweden. Materials and methods Intestinal duodenal biopsies were collected from 402 chil

Tumour-educated macrophages display a mixed polarisation and enhance pancreatic cancer cell invasion.

At the time of diagnosis, almost 80% of pancreatic cancer patients present with new-onset type 2 diabetes (T2D) or impaired glucose tolerance. T2D and pancreatic cancer are both associated with low-grade inflammation. Tumour-associated macrophages (TAMs) have a key role in cancer-related inflammation, immune escape, matrix remodelling and metastasis. In this study, the interplay between tumour cel

Consequences of Subpopulation Structure on Fisheries Management: Cod (Gadus morhua) in the Kattegat and Oresund (North Sea)

This study shows how cod subpopulations may have been eradicated as a consequence of the use of imperfect models for assessing stock assessment, depleting what was formerly a productive sea. The Kattegat and Oresund (North Sea) were chosen as study objects due to the combination of different exploitation patterns and the possible existence of separate stock units. The scenario was further elaborat

Sol-Gel Derived Nanoporous Compositions for Entrapping Small Molecules and Their Outlook toward Aptamer Screening

This paper reports for the first time the application of sol-gel microarrays for immobilizing nonsoluble small chemicals (Bisphenol-A; BPA). Also, known problems of sol-gel adhesion to conventional microtiter well plate substrates are circumvented by anchoring the sol-gel microspots to a porous silion surface so-called, PS-SG chips. We confirmed low molecular weight chemical immobilization inside

Age-associated changes in hypothalamic-pituitary-testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European Male Ageing Study

Objective: Health and lifestyle factors are associated with variations in serum testosterone levels in ageing men. However, it remains unclear how age-related changes in testosterone may be attenuated by lifestyle modifications. The objective was to investigate the longitudinal relationships between changes in health and lifestyle factors with changes in hormones of the reproductive endocrine axis

Six-dimensional real and reciprocal space small-angle X-ray scattering tomography.

When used in combination with raster scanning, small-angle X-ray scattering (SAXS) has proven to be a valuable imaging technique of the nanoscale, for example of bone, teeth and brain matter. Although two-dimensional projection imaging has been used to characterize various materials successfully, its three-dimensional extension, SAXS computed tomography, poses substantial challenges, which have ye

Coupling planktonic and benthic shifts during a bloom of Alexandrium catenella in southern Chile: Implications for bloom dynamics and recurrence

Cell abundances and distributions of Alexandrium catenella resting cysts in recent sediments were studied along time at two locations in the Chilean Inland Sea exposed to different oceanographic conditions: Low Bay, which is much more open to the ocean than the more interior and protected Ovalada Island. The bloom began in interior areas but maximum cyst concentrations were recorded in locations m

Dissolution of dissolving pulp in alkaline solvents after steam explosion pretreatments

In this project different aqueous based solvent systems were investigated for the dissolution of steam exploded (STEX) dissolving pulps prior to a coagulation step for preparation of textile fibers. The pulp samples studied could, to a large degree, be dissolved in a NaOH/urea/thiourea system, but there are always residuals, irrespective of the conditions. The dissolution process appeared to be ki

Value-driven purchasing of kitchen cabinets in industrialised housing

Purpose – The purpose of this paper is to hypothesize that value-driven purchasing of customized kitchen cabinets is more profitable than market-driven purchasing in industrialised housing construction. The hypothesis is examined through a case study of kitchen carpentry at one of the Sweden's largest producers of industrialised prefabricated multi-storey housing. By comparing characteristics of m

Work experience and the generation of new business ideas among entrepreneurs: An integrated learning framework

Abstract in UndeterminedPurpose – This paper seeks to develop an integrated framework to examine how entrepreneurs' work experience is associated with the generation of new business ideas. The framework combines human capital theory with theory and research on entrepreneurial learning.Design/methodology/approach – A statistical analysis on a sample of 291 Swedish entrepreneurs is conducted.Finding

Prediction of alignment deviations on a lead crowned helical gear manufactured by a hob

A drawback when hobbing lead crowned helical gears is that the gear tooth will be manufactured with alignment errors, often denoted flank twist. Together with other source deviations, these errors must not exceed the predetermined tolerances if the gear is to be finished hobbed. A simulation model is developed where the hobbing process can be analysed without additional errors resulting from real

Optimal feedforward compensators for systems with right-half plane zeros

Feedforward from measurable disturbances is a powerful complement to feedback control to improve disturbance rejection capability. Recent works have remarked the necessity of a design strategy for those cases where the ideal feedforward controller is not realizable. In this paper, a simple shaping design procedure is presented together with straightforward rules to obtain optimal feedforward contr