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Brandskyddshandboken 2014

Utvecklingen inom det brandskyddstekniska området går snabbt vilket, tillsammans med nya byggföreskrifter, motiverar att denna handbok tas fram. Brandskyddslaget, Bengt Dahlgren Brand & Risk och Brandteknik LTH publicerar sedan några år Brandskyddshandboken som förklarar och förtydligar BBR:s brandskyddsavsnitt. Nu när BBR 21 med stora ändringar tillämpas, har vi tagit fram en ny uppdaterad o

On the relations between water regime, mass accretion and formation of ombrotrophic conditions in Sphagnum mires

(1) I explore the hypothesis that the water regime is one of the major determinants of the difference between bog and fen in Sphagnum mires because of its effects on the decay loss and the mass accretion rate. This article deals with the recent mass balance and water regime and the variation in mass accretion rate during the last millennium, studied at two mires in southern Sweden. (2) At one bog

Characterisation of de novo mutations in the C-terminal domain of proprotein convertase subtilisin/kexin type 9.

Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes the degradation of the hepatic low-density lipoprotein receptor (LDL-R) and is therefore a prominent therapeutic target for reducing LDL-cholesterol. The C-terminal domain of PCSK9 is unlikely to be involved in a direct extracellular interaction with the LDL-R. We probed the importance of the C-terminus for the degradation of the LDL-R

Forest-edge effects on sea-salt aerosol deposition: a wind-tunnel study using living oak leaves

Landscape patchiness creates aerodynamic transition zones that affect the exchange of nutrients and pollutants between the atmosphere and vegetation. Using an artificially-generated NaCl aerosol (mass-versus-particle-size distribution with aerodynamic mean particle diameter 1.6 mu m; geometric standard deviation 1.9), we investigated the forest-edge effect on aerosol deposition within a model oak

Tit for tat? A mycorrhizal fungus accumulates phosphorus under low plant carbon availability.

The exchange of carbohydrates and mineral nutrients in the arbuscular mycorrhizal symbiosis must be controlled by both partners in order to sustain an evolutionarily stable mutualism. Plants down-regulate their carbon flow to the fungus when nutrient levels are sufficient, while the mechanism controlling fungal nutrient transfer is unknown. Here we show that the fungus accumulates nutrients when c

Familial risk and familial survival in prostate cancer

The Swedish Family-Cancer Database has been the major source of population-based prospective data on familial risks on most cancers, including prostate cancer. In the present review, I focus on three lines of family studies with novel results. The covered studies originate from the same database with publication dates spanning a period of somewhat over 3 years. Age-specific hazard ratios (HRs) of

Isobaric Tagging-Based Quantification for Proteomic Analysis: A Comparative Study of Spared and Affected Muscles from mdx Mice at the Early Phase of Dystrophy

Duchenne muscular dystrophy (DMD) is the most common childhood myopathy, characterized by muscle loss and cardiorespiratory failure. While the genetic basis of DMD is well established, secondary mechanisms associated with dystrophic pathophysiology are not fully clarified yet. In order to obtain new insights into the molecular mechanisms of muscle dystrophy during earlier stages of the disease, we

Uptake of atrial fibrillation screening aiming at stroke prevention: geo-mapping of target population and non-participation

Background: In a screening study for silent atrial fibrillation (AF), which is a frequent source of cardiac emboli with ischemic stroke, the proportion of non-participants was considerable and their clinical profile differed from the participants' profile. We intended to geo-map the target population and non-participation in an attempt to understand factors related to screening uptake and, thereby

Proteolysis of purified IgGs by human and bacterial enzymes in vitro and the detection of specific proteolytic fragments of endogenous IgG in rheumatoid synovial fluid

A comparative in vitro survey of physiologically relevant human and microbial proteinases defined a number of enzymes that induced specific hinge domain cleavage in human IgG1. Several of these proteinases have been associated with tumor growth, inflammation, and infection. A majority of the identified proteinases converted IgG to F(ab')(2), and a consistent feature of their action was a transient

Characterization of New Particle Formation Events at a Background Site in Southern Sweden: Relation to Air Mass History

Particle formation events were analysed from aerosol number size distribution data collected at a background station in southern Sweden between February 2001 and May 2004. Events occurred on about 36% of all days and were favoured by high global radiation values. The clearest events (class I, 20% of all days) were observed when the formation rate of activated hypothetical clusters around 1 nm diam

Molecular mechanisms underlying morphological effects of protein kinase C under normal conditions and cellular stress.

The protein kinase C (PKC) family of serine/threonine kinases consists of 10-15 members. The PKC isoforms have central roles in many essential cellular processes, including proliferation, apoptosis, differentiation, cytoskeletal changes, and migration. The PKC family can be subgrouped into classical, novel and atypical isoforms depending on structure and sensitivity to the activators diacylglycero

Transposable Elements in Neural Progenitor Cells

Popular Abstract in English In an organism the DNA contains the entire biological information that is needed to be able to exist and function. Those segments, also known as DNA sequences are a genetic code, which is further packaged into units called genes. The entity of all genes is called genome. Today we know, that only a small proportion of genes encode for proteins, which are responsible for More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. Transposable elements comprise about 50% of the genome and co-exist as symbio

Falling in love with a wheelchair. Enabling/disabling technologies

Abstract in UndeterminedThe aim of this article is to explore how young women with physical impairments make use of technology in their identity construction, drawing on the metaphor of the cyborg as well as on science and technology studies and disability research. In addition to participant observation, semi-structural interviews were conducted and video diaries were kept of the women playing sl