Objectives: The present study aimed to identify multidimensional typologies of harmful alcohol use based on the Swedish Addiction Severity Index (ASI) assessment data on individuals aged 50 years and above.Methods: Latent class analysis examined 11 indicators from ASI data on 1747 individuals (men = 1255, women = 492) who reported they were troubled by alcohol problem at least one day in the past

Background: Intensive care units (ICUs) are hot zones for emergence and spread of antibiotic resistance because of frequent invasive procedures, antibiotic usage and transmission of bacteria. We report prospective data on antibiotic use and bacterial resistance from 14 academic and non-academic ICUs, participating in the ICU-STRAMA programme 1999-2003. Methods: The quantity of antibiotics delivere

Critical raw materials (CRM) are extensively used in tools for metal cutting, such as in cemented carbide tools (cobalt and tungsten), because they provide desired characteristics of high fracture toughness and wear resistance. Both academia and industry are examining CRM-free material alternatives, such as tools based on polycrystalline diamond (PCD) or ceramic materials. These materials are gene

Within the field of tourism information search behaviour, this research aims at exploring the proposed concept of ‘planned serendipity’ and its connection with smartphone use for tourism information search. Although studies on smartphone and tourism have flourished in the past few years, research on information needs and how these needs exist in relation to smartphones is lacking. Moreover, there

Background of the study One of the main challenges in tourism research is to find effective methodologies to capture the salient moments that make a tourist experience memorable (Cary, 2004; Tussyadiah, 2014). A gap exists between the tourist experience – which happens at a destination, during the time of the trip – and the recollection of it during the study – which often happens days, weeks or m

Incomplete lysosomal acidification in microglia inhibits the degradation of fibrillar forms of Alzheimer's amyloid β peptide (fAβ). Here we show that in primary microglia a chloride transporter, ClC-7, is not delivered efficiently to lysosomes, causing incomplete lysosomal acidification. ClC-7 protein is synthesized by microglia but it is mistargeted and appears to be degraded by an endoplasmic re

The importance of networking is often emphasized in higher education teaching and learning. In this article we discuss significant networks and their impact on pedagogical development. We also share our experience of working in different kinds of networks. We focus on a Nordic project with the aim to develop digital learning objects in co-creation between librarians, students and teachers.

High sound levels related to medical equipment and high activity day and night, is a wellknown phenomenon in intensive care units (ICUs). This may result in poor sleep and prolonged recovery for the patients but may also be a precipitating factor for intensive care delirium (ICU delirium).The aim of this pilot study was to describe patients' responses to the sound environment in an ICU and to iden

The SWEDEGRAFT study (ClinicalTrials.gov Identifier: NCT03501303) tests the hypothesis that saphenous vein grafts (SVGs) harvested with the “no-touch” technique improves patency of coronary artery bypass grafts compared with the conventional open skeletonized technique. This article describes the rationale and design of the randomized trial and baseline characteristics of the population enrolled d

To overcome the large discrepancy in speed between computational devices and that of contemporary large capacity non-volatile memory (NVM) technologies, resistive random access memory (RRAM) technologies are seen as promising candidates, offering speed/energy improvements in several orders of magnitude while being 3D integration compatible [1]. Indium-Tin-Oxide (ITO) has several unique properties

According to the Global Burden of Disease study, occupational exposures to particulates, gases and fumes were responsible for 0.36 million deaths and 8.8 million disability-adjusted life years globally in 2015. This thesis focuses on two occupational groups that are at risk for developing adverse health effects from the time they spend in their working environments: cleaning workers and workers in

Before his unexpected victory in Ukraine’s presidential elections, the comedian and political novice Volodymyr Zelensky’s engagement with civil society was almost non-existent. The last two years of former president Petro Poroshenko were marked for civil society organizations (CSO) – in particular those working on human rights, anti-corruption, and media freedom – by numerous obstacles, including