Combined effects of environmental xeno-estrogens within multi-component mixtures : Comparison of in vitro human- and zebrafish-based estrogenicity bioassays
Some recent studies showed that in vitro bioassays based on fish or human estrogen receptor (ER) activation may have distinct responses to environmental samples, highlighting the need to better understand bioassay-specific ER response to environmental mixtures. For this purpose, we investigated a 12-compound mixture in two mixture ratios (M1 and M2) on zebrafish (zf) liver cells stably expressing
