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Patient choice as a means of empowerment in opioid substitution treatment : a case from Sweden

Patient choice of treatment provider was introduced within opioid substitution treatment in the southern Swedish county of Skåne in 2014. Substitution treatment has often been criticised for being strict, rule-based, and driven by an ethos of discipline. This study explores the patients’ views and experiences of patient choice, particularly as a potential means of empowerment. The study is based o

Metabolic engineering of yeast for improved whole-cell biocatalytic amine production

Saccharomyces cerevisiae has emerged as a versatile platform for whole-cell biocatalysis, owing to its intrinsic regeneration of cofactors and amenability to genetic engineering. However, efficient reductive amination of aromatic carbonyls remains challenging due to competing redox pathways and product inhibition by pyruvate. Building on the redox-rewired TMB4133 strain (∆gpd1,2) that accumulates

Association of Osteopontin and selective glomerular hypofiltration syndrome with hospitalization for kidney failure in acute heart failure patients

BACKGROUND: Selective glomerular hypofiltration syndrome (SGHS), formerly shrunken pore syndrome, an emerging marker of glomerular dysfunction, is associated with worsened prognosis in cardiovascular disease, but its role in kidney failure remains underexplored. Osteopontin (OPN) is associated with worsening kidney function and prognosis in chronic kidney disease.PURPOSE: To explore if increased l

Janus kinase 1 inhibitors for treating immune checkpoint inhibitor-induced enterocolitis - report of two filgotinib-treated cases and literature review

BACKGROUND AND PURPOSE: Treatment of cancer with immune checkpoint inhibitors (ICIs) entails a risk of immune-related adverse events (irAEs). Data on the treatment of immune-related enterocolitis (irEC) in patients with inadequate symptom control after treatment with standard therapy including corticosteroids, infliximab, and vedolizumab are scarce. Based on limited data, recommendations include t

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The Öresund – the strait between eastern Denmark and southwestern Sweden – is an ancient focal point for trade, conflict, and cooperation in Northern Europe. The control of the strait has been of utmost strategic importance in Northern Europe over the centuries, involving several wars between Denmark and Sweden. During the 19th and 20th centuries, a decidedly more peaceful relationship developed b

Effects of Maternal Use of the Continuum of Care on Complementary Feeding Practices in Bangladesh: Cross-Sectional Study

Background: The continuum of care (CoC) for maternal health, which includes ≥4 antenatal care (ANC) visits, delivery assisted by skilled birth attendants, and a postnatal care (PNC) visit within 48 hours of delivery, is a crucial health care package associated with survival and improved health outcomes for children and mothers. In addition, the CoC serves as a platform for delivering messages and

The Onboarding Journey: From Attracting to Belonging A Thematic Literature Review Examining the Onboarding Process

Onboarding is a critical and strategically important process that significantly affects an organization's ability to attract, retain and engage new top talents in today’s competitive and rapidly evolving labor market. Despite a vast amount of research emphasizing the importance and benefits from having a structured onboarding process, many organizations continue to rely on outdated strategies

Generation, Self-assembly, and Characterisation of Medium-entropy Fe0.10Ni0.40Co0.25Pt0.25 Nanoparticles

The ongoing pursuit of advanced multicomponent magnetic nanomaterials with tailored functionalities for applications in data storage, spintronics, and biomedicine necessitates novel synthesis approaches beyond conventional template-based methods. In response, this thesis investigates the generation, self-assembly, and characterisation of largely little-known Fe0.10Ni0.40Co0.25Pt0.25 medium-entropy

Approaching 100Sn : Structural evolution in 98,100Cd via lifetime measurements

The lifetimes of low-lying excited states below the 8+ seniority isomer were directly measured using fast timing detectors in the neutron-deficient isotopes 98,100Cd. This experiment was conducted with the DEcay SPECtroscopy (DESPEC) setup at GSI, where the ions of interest were produced via a fragmentation reaction and identified using the FRagment Separator (FRS) before being implanted in the AI

Inspelning och tillgängliggörande av konserter och idrottsevenemang - Ett upphovsrättsligt perspektiv

Denna uppsats behandlar de rättsliga frågor som uppstår när konserter och idrottsevenemang spelas in, laddas upp eller livestreamas. Bakgrunden är att sådana videor ofta laddas upp på internet, vilket aktualiserar både upphovsrättsliga och avtalsrättsliga frågor. Syftet med uppsatsen är att analysera rättsläget kring inspelning och tillgängliggörande av konserter och idrottsevenemang. Metoden soThis thesis addresses the legal issues that arise when concerts and sporting events are recorded, uploaded or livestreamed. The background is that such videos are often uploaded to the internet, which raises both copyright and contract law questions. The purpose of the thesis is to analyse the legal situation regarding the recording and making available of concerts and sporting events. The method

Beskattningstidpunkten för derivatinstrument som säkrar skulder i utländsk valuta - En rättsdogmatisk analys av gällande svensk rätt i ljuset av kammarrätten i Stockholms dom i mål nr. 1858-24

Detta arbete behandlar beskattningstidpunkten för derivatinstrument som säkrar skulder i utländsk valuta, enligt svensk rätt. Detta är intressant eftersom svenska företag i en globaliserad ekonomi exponeras mot valutarisker. Det råder dock osäkerheter om när säkringsderivatet ska beskattas. Uppsatsen analyserar därför hur den rättsliga regleringen i IL påverkar beskattningstidpunkten av värdeföränThis thesis examines the timing of taxation of derivatives hedging foreign-currency liabilities under Swedish law. The issue is interesting given the currency risk exposure of Swedish enterprises in a globalized economy, yet uncertainty persists as to when hedging derivatives are recognized as taxable income. The study analyses how the Swedish income tax law governs the recognition of value change

Ansiktsigenkänning med AI-system

Uppsatsen behandlar det rättsliga läget i Sverige för användningen av AI-system vars syfte är att utföra ansiktsigenkänning. Polismyndighetens användning av tekniken står i centrum för analysen. Användningen möjliggörs av AI-förordningen som reglerar när aktörer får eller inte får använda olika typer av AI-system. I förordningen regleras bland annat situationer då en behörig myndighet som exempelvThis thesis examines the legal framework concerning AI systems for facial recognition. The main focus is on the Swedish Police Authority’s use of the technology. The AI Act is the main legal text governing AI systems and it regulates when different types of AI systems may be used. The AI Act includes regulation surrounding the use of AI systems for facial recognition by, for example, the Swedish P

The Killer That Got Away? EU Competition Law and the Challenge of Killer Acquisitions in Pharma and Medtech

Killer acquisitions refer to a strategic subset of mergers and acquisitions (M&A) in which dominant firms acquire innovative start-ups to eliminate potential future competition. These transactions have become increasingly prevalent in the pharmaceutical and medical technology sectors, where start-ups often possess valuable innovation assets despite generating little or no current turnover. Con

Hur bör handel med kryptovalutor beskattas - En rättsdogmatisk utredning om beskattning av kryptovalutor

Studien syftar till att rättsdogmatiskt undersöka hur kryptovalutor ska beskattas enligt svensk inkomstskattelag. Uppsatsen analyserar även hur denna nya typ av valuta bör klassificeras enligt gällande rätt samt vilket inkomstslag som är mest tillämpbar vid beskattning. Studien grundas på lagstiftning, förarbeten, praxis från Högsta förvaltningsdomstolen, uttalanden från Skatteverket och doktrin. This study aims to conduct a legal dogmatic analysis of how cryptocurrencies should be taxed under the Swedish income Tax Act. The thesis examines how this new type of currency should be classified under current law and which income category is most applicable for taxation. The study is based on legislation, preparatory works, case law from the Swedish Supreme Administrative Court (Högsta förvaltn