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A parametric comparison of temperature uniformity and energy performance of a PEMFC having serpentine wavy channels

Proton exchange membrane fuel cells (PEMFCs) are regarded as alternative energy sources because they are environment friendly and deliver no harmful emission. As its reliability and power generating efficiency is largely influenced by the temperature distribution, it is necessary to improve the temperature uniformity which is crucial in PEMFCs. To this end, this numerical study presents an attempt

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome

RATIONALE: Ischemic stroke is among the leading causes of adult disability. Part of the variability in functional outcome after stroke has been attributed to genetic factors but no locus has been consistently associated with stroke outcome. OBJECTIVE: Our aim was to identify genetic loci influencing the recovery process using accurate phenotyping to produce the largest GWAS (genome-wide associatio

Preventing falls among older fallers : Study protocol for a two-phase pilot study of the multicomponent LIVE LiFE program

Background: Falls reflect sentinel events in older adults, with significant negative consequences. Although fall risk factors have been identified as intrinsic (e.g., muscle weakness, balance problems) and extrinsic (e.g., home hazards), most prevention programs target only intrinsic factors. We present the rationale and design of a home-based multicomponent fall prevention program - the LIVE LiFE

An Industrial Case Study on Test Cases as Requirements

It is a conundrum that agile projects can succeed ‘without requirements’ when weak requirements engineering is a known cause for project failures. While Agile development projects often manage well without extensive requirements documentation, test cases are commonly used as requirements. We have investigated this agile practice at three companies in order to understand how test cases can fill the

Thoracoabdominal gastrectomy and distal 2/3 esophageal resection with wide lymph node dissection for type II and III adenocarcinoma at the gastro-esophageal junction

Background: For locally advanced Siewert type II and III tumors we have performed total gastrectomy including resection of the distal 2/3 of the esophagus, through separate abdominal and right chest incisions (THX-ABD). The procedure involves wide lymphadenectomy in the abdomen/chest and a Roux-en-Y jejunostomy to the level of the azygos vein or above. The aim of the study was to investigate short

Student visas, undocumented labor, and the boundaries of legality : Chinese migration and English as a foreign language education

This article studies Chinese student migrants who are at risk of becoming undocumented through their engagement with the labour market in the Republic of Ireland. The migrants I am concerned with are not elite dual-passport holders, but rather individuals who strategically participate in transnational migration as part of an emerging Chinese middle class. By closely examining the interrelation bet

Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production

Diabetes is a bihormonal disorder resulting from combined insulin and glucagon secretion defects. Mice lacking fumarase (Fh1) in their β cells (Fh1βKO mice) develop progressive hyperglycemia and dysregulated glucagon secretion similar to that seen in diabetic patients (too much at high glucose and too little at low glucose). The glucagon secretion defects are corrected by low concentrations of tol

Search for pair and single production of vectorlike quarks in final states with at least one Z boson decaying into a pair of electrons or muons in pp collision data collected with the ATLAS detector at s =13 TeV

A search for vectorlike quarks is presented, which targets their decay into a Z boson and a third-generation Standard Model quark. In the case of a vectorlike quark T (B) with charge +2/3e (-1/3e), the decay searched for is T→Zt (B→Zb). Data for this analysis were taken during 2015 and 2016 with the ATLAS detector at the Large Hadron Collider and correspond to an integrated luminosity of 36.1 fb-1

Anti-EF-Tu IgG titers increase with age and may contribute to protection against the respiratory pathogen Haemophilus influenzae

Non-typeable Haemophilus influenzae (NTHi) is a pathogen that commonly colonizes the nasopharynx of preschool children, causing opportunistic infections including acute otitis media (AOM). Patients suffering from chronic obstructive pulmonary disease (COPD) are persistently colonized with NTHi and occasionally suffer from exacerbations by the bacterium leading to increased morbidity. Elongation-fa

Business models for sustainable consumption in the circular economy : An expert study

Combining sustainable consumption with the circular economy concept could help tackle challenges, such as resource scarcity and climate change by reducing resource throughput and increasing cycling of products and materials within the economic system, thereby reducing emissions and virgin material use. To achieve sustainable consumption in a circular economy production and consumption practices ne

Insulin induces Thr484 phosphorylation and stabilization of SIK2 in adipocytes

AIMS/HYPOTHESIS: Salt-inducible kinase 2 (SIK2) is downregulated in adipose tissue from obese or insulin-resistant individuals and inhibition of SIK isoforms results in reduced glucose uptake and insulin signalling in adipocytes. However, the regulation of SIK2 itself in response to insulin in adipocytes has not been studied in detail. The aim of our work was to investigate effects of insulin on v

Are values related to culture, identity, community cohesion and sense of place the values most vulnerable to climate change?

Values related to culture, identity, community cohesion and sense of place have sometimes been downplayed in the climate change discourse. However, they have been suggested to be not only important to citizens but the values most vulnerable to climate change. Here we test four empirical consequences of the suggestion: (i) at least 50% of the locations citizens' consider to be the most important lo

Detailed analysis of health-related quality of life after out-of-hospital cardiac arrest

Aim: To describe the detailed health-related quality of life (HRQoL) in survivors from the TTM-trial and to investigate potential differences related to sex and age. Methods: This is a cross-sectional study originating from a large prospective international, multicentre trial, including 442 respondents who answered the Short Form-36 item Questionnaire Health Survey version 2® (SF-36v2®) at a struc

Automated phosphopeptide enrichment from minute quantities of frozen malignant melanoma tissue

To acquire a deeper understanding of malignant melanoma (MM), it is essential to study the proteome of patient tissues. In particular, phosphoproteomics of MM has become of significant importance because of the central role that phosphorylation plays in the development of MM. Investigating clinical samples, however, is an extremely challenging task as there is usually only very limited quantities

QCD multiplet bases with arbitrary parton ordering

We develop an algorithm for recursively constructing orthogonal multiplet bases for the color space of QCD, for any order of partons and any Nc. This recipe is then applied for explicitly constructing some of these bases. Using the bases, a corresponding set of Wigner 6j coefficients are calculated. The Wigner coefficients offer a method of using multiplet bases without resorting to the explicit e