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gamma -carboxylated polypeptides were detected in the human kidney by immunohistochemistry with a monoclonal antibody (M3B) specific for gamma -carboxyglutamyl residues. An similar to 70-kDa gamma -carboxylated protein, subsequently identified as prothrombin, was isolated from the intracellular compartment of cultured human embryonic kidney (HEK293) cells by immunoaffinity chromatography on M3B-co
High-grade gliomas are one of the most aggressive human tumors with <1% of patients surviving 5 years after surgery. Immunotherapy could offer a possibility to eradicate remnant tumor cells after conventional therapy. Experimental immunotherapy can induce partial cure of established intracerebral tumors in several rodent models. One reason for the limited therapeutic effects could be immunosuppres
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The immune and the detoxication systems of animals are characterized by allelic polymorphisms, which underlie individual differences in ability to combat assaults from pathogens and toxic compounds. Previous studies have shown that females may improve offspring survival by selecting mates on the basis of sexual ornaments and signals that honestly reveal health. In many cases the expression of thes
Ectomycorrhizal (EM) fungi are known to colonize minerals in forest soil, and in many laboratory experiments it has been confirmed that EM fungi stimulate dissolution of minerals such as apatite, biotite and feldspars. However, due to the low number of experiments performed in the field, and in forests with different soil fertilities, it is difficult to conclude whether this effect has any ecologi
Rapporten är en probleminventering av beständighetsproblem i samband med putsade fasader. I rapporten redovisas ett 10-tal typiska exempel på de vanligaste problemen, utan att diskutera skadeorsaker eller orsaksfrågor. Inventeringen avslutas med ett översiktligt forskningsprogram med inriktning på sprickbildning i puts på isolering och missfärgning av mineraliska ytskikt.
Abstract is not available
The influence of continuous inhalation of 150 ppm trichloroethylene (TCE) on body, liver, spleen, and kidney weights in rats, mice, and mongolian gerbils was tested. An age dependent decrease in body weight gain was observed in female rats exposed to TCE. All 3 spcies showed liver enlargement caused by the exposure. The effect was much more pronounced in mice, in which the increase was 60–80%, th
Background Ligands of peroxisome proliferator-activated receptor alpha (PPAR-alpha) have been shown to reduce ischaemia/reperfusion injury. The mechanisms behind this effect are not well known. We hypothesized that activation of PPAR-alpha exerts cardioprotection via a mechanism related to nitric oxide (NO) and endothelin-1 (ET-1). Methods Five groups of anaesthetized open-chest Sprague-Dawley rat
Twenty patients with carcinoma of the pancreas identified with ultrasonography and/or CT and confirmed by histology, were examined with MR before and after administration of an oral super-paramagnetic contrast medium. Ten patients were examined after administration of the contrast medium through a duodenal tube. Ten patients drank the contrast medium mixed with a viscosity-increasing agent. Organ
Aims To examine the prognostic importance of weight-change in patients with coronary artery disease (CAD), especially following acute myocardial infarction (AMI). Methods and results In 4360 AMI patients (OPTIMAAL trial) without baseline oedema, we assessed 3-month weight-change, baseline body mass index (BMI), demographics, patient history, medication, physical examination, and biochemical analys
I denna rapport ges några bilder av ekonomen i Sveriges kommuner och landsting. Förhoppningen är att dessa bilder bl.a. kan ge ett bidrag till de egenskaper och roller som tilldelas sektorns ekonomer. Bilderna förmedlas av den volymmässigt största andelen av sektorns ekonomer, d.v.s. de ekonomer som kan sägas vara underordnade en ekonomichef eller förvaltningschef. En fjärdedel av de nästan 600 ek
Adaptive tracking of non-linear dynamic plants is currently an important area of research. The main difficulty being felt by the research community is the lack of a general modelling framework that can facilitate synthesis of a simplistic control law while being capable of providing accurate approximation of non-linear systems. In this study a novel technique based on the control-oriented U-model
