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To feel like an outsider: focus group discussions regarding the influence on sexuality caused by breast cancer treatment.
The aftermath of breast cancer treatment, especially the sexual side effects, appears to be a neglected issue in developed society. The purpose of this study was to explore how middle-aged women treated for a breast cancer experienced their sexual identity connected to the community norms and values in the society as a whole. Three focus group interviews were conducted, with a total of 12 women. T
Mesenteric ischemia.
Diagnosis of acute mesenteric ischemia in the early stages is now possible with modern computed tomography (CT), using intravenous contrast enhancement and imaging in the arterial and/or portal venous phase. The availability of CT around the clock means that more patients with acute mesenteric ischemia may be treated with urgent intestinal revascularization.
Pathogen Entrapment by Transglutaminase-A Conserved Early Innate Immune Mechanism
Clotting systems are required in almost all animals to prevent loss of body fluids after injury. Here, we show that despite the risks associated with its systemic activation, clotting is a hitherto little appreciated branch of the immune system. We compared clotting of human blood and insect hemolymph to study the best-conserved component of clotting systems, namely the Drosophila enzyme transglut
Anne Brontë and her Bible
Does the Decoupling Reform Affect Agricultural Employment in Sweden? Evidence from an Exogenous Change
This study uses aggregated municipality data, for the years 2001-2009, to explore whether direct payments to farmers affect agricultural employment in Swedish municipalities. The decoupling reform in 2005 included a new grassland support payment accompanied by management obligations that had unexpectedly high redistributive consequences as it greatly increased common agricultural policy payments t
Selection and evolutionary potential of spring arrival phenology in males and females of a migratory songbird
The timing of annual life-history events affects survival and reproduction of all organisms. A changing environment can perturb phenological adaptations and an important question is if populations can evolve fast enough to track the environmental changes. Yet, little is known about selection and evolutionary potential of traits determining the timing of crucial annual events. Migratory species, wh
Opposition Coalitions and Democratization by Elections
Comparative friction measurements of InAs nanowires on three substrates
We have investigated friction between InAs nanowires and three different substrates: SiO2, fluorosilanized SiO2, and Si3N4. The nanowires were pushed laterally with the tip of an atomic force microscope and the friction force per unit length for both static and sliding friction was deduced from the equilibrium shape of the bent wires. On all three substrates, thick wires showed a difference betwee
Toward a Silver-Alumina Model System for NOx Reduction Catalysis
The growth and morphology of Ag deposited on NiAl(110) and on oxidized NiAl(110) have been investigated by a combination of scanning tunneling microscopy (STM) and high-resolution core-level spectroscopy (HRCLS). While the STM measurements reveal complete wetting and a bilayer growth on clean NiAl(110), Ag nanoparticles with a minimum size of 5 nm were obtained on the oxidized NiAl(110). The diffe
Genotype-based treatment of type 2 diabetes with an α2A-adrenergic receptor antagonist.
The feasibility of exploiting genomic information for individualized treatment of polygenic diseases remains uncertain. A genetic variant in ADRA2A, which encodes the α2A-adrenergic receptor (α2AAR), was recently associated with type 2 diabetes. This variant causes receptor overexpression and impaired insulin secretion; thus, we hypothesized that blocking α2AAR pharmacologically could improve insu
Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers
Two single nucleotide polymorphisms (SNPs) at 6q25.1, near the ESR1 gene, have been implicated in the susceptibility to breast cancer for Asian (rs2046210) and European women (rs9397435). A genome-wide association study in Europeans identified two further breast cancer susceptibility variants: rs11249433 at 1p11.2 and rs999737 in RAD51L1 at 14q24.1. Although previously identified breast cancer sus
Apolipoprotein E Genotype and the Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers for Alzheimer Disease.
Several studies suggest that the apolipoprotein E (APOE) ε4 allele modulates cerebrospinal fluid (CSF) levels of β-amyloid 42 (Aβ42). Whether this effect is secondary to the association of the APOE ε4 allele with cortical Aβ deposition or whether APOE ε4 directly influences CSF levels of Aβ42 independently of Aβ pathology remains unknown.
Gas6 fueling tumor-mediated thrombosis.
Diagnostic performance of the Selvester QRS scoring system in relation to clinical ECG assessment of patients with lateral myocardial infarction using cardiac magnetic resonance as reference standard.
The Selvester QRS scoring system has previously been shown to enable estimation of myocardial infarct (MI) size by quantitative evaluation of the 12-lead ECG. The aim of this study was to assess the system's ability to detect and quantify lateral MI, using cardiac magnetic resonance (CMR) as reference standard.
The ontogeny of Ellipsocephalus (Trilobita) and systematic position of Ellipsocephalidae
Laibl, L., Fatka, O., Budil, P., Ahlberg, P., Szabad, M., Voka, V. & Kozak, V., 24.3.2015. The ontogeny of Ellipsocephalus (Trilobita) and systematic position of Ellipsocephalidae. Alcheringa 39, 477-487. ISSN 0311-5518.Well-preserved early holaspid stages of the Cambrian Series 3 trilobites Ellipsocephalus hoffi (Schlotheim, 1823) and Ellipsocephalus polytomus Linnarsson, 1877 have been disco
Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood
The origins of allergic asthma, particularly in infancy, remain obscure. Respiratory viral infections and allergen sensitization in early life have been associated with asthma in young children. However, a causal link has not been established. We investigated whether an influenza A infection in early life alters immune responses to house dust mite (HDM) and promotes an asthmatic phenotype later in
Investigation of the mediated electron transfer mechanism of cellobiose dehydrogenase at cytochrome c-modified gold electrodes
The present study reports on the comparison of direct and mediated electron transfer pathways in the interaction of the fungal enzyme cellobiose dehydrogenase (CDH) with the redox protein cytochrome c (cyt c) immobilised at a modified gold electrode surface. Two types of CDHs were chosen for this investigation: a basidiomycete (white rot) CDH from Trametes villosa and a recently discovered ascomyc
Measurement of transverse-single-spin asymmetries for midrapidity and forward-rapidity production of hadrons in polarized p plus p collisions at root s=200 and 62.4 GeV
Measurements of transverse-single-spin asymmetries (A(N)) in p + p collisions at root s = 62.4 and 200 GeV with the PHENIX detector at the Relativistic Heavy Ion Collider are presented. At midrapidity, A(N) is measured for neutral pion and eta mesons reconstructed from diphoton decay, and, at forward rapidities, neutral pions are measured using both diphotons and electromagnetic clusters. The neut
Probabilistic Joint Image Segmentation and Labeling by Figure-Ground Composition
We propose a layered statistical model for image segmentation and labeling obtained by combining independently extracted, possibly overlapping sets of figure-ground (FG) segmentations. The process of constructing consistent image segmentations, called tilings, is cast as optimization over sets of maximal cliques sampled from a graph connecting all non-overlapping figure-ground segment hypotheses.
