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Editor's Choice-Is the pre-hospital ECG after out-of-hospital cardiac arrest accurate for the diagnosis of ST-elevation myocardial infarction?

BACKGROUND: Current guidelines recommend that comatose out-of-hospital cardiac arrest patients with ST-segment elevations (STEs) following return of spontaneous circulation (ROSC) should be referred for an acute coronary angiography. We sought to investigate the diagnostic value of the pre-hospital ROSC-ECG in predicting ST-elevation myocardial infarction (STEMI).METHOD: ROSC-ECGs of 145 comatose

Diabetic patients with acute coronary syndromes in contemporary European registries : Characteristics and outcomes

Aims Among patients with acute coronary syndromes (ACS), those with diabetes mellitus (DM) are at particularly high risk of recurrent cardiovascular events and premature death. We aimed to provide a descriptive overview of unadjusted analyses of patient characteristics, ACS management, and outcomes up to 1 year after hospital admission for an ACS/index-ACS event, in patients with DM in contemporar

P2Y12 receptor inhibitors in patients with non-STelevation acute coronary syndrome in the real world : Use, patient selection, and outcomes from contemporary European registries

Aims Non-ST-elevation acute coronary syndrome (NSTE-ACS) is present in about 60-70% of patients admitted with acute coronary syndromes in clinical practice. This study provides a 'real-life' overview of NSTE-ACS patient characteristics, dual antiplatelet therapy clinical practice, and outcomes at both the time of discharge from hospital and up to 1-year post-discharge. Methods and results A total

Use, patient selection and outcomes of P2Y12 receptor inhibitor treatment in patients with STEMI based on contemporary European registries

Aims Among acute coronary syndromes (ACS), ST-segment elevation myocardial infarction (STEMI) has the most severe early clinical course. We aimed to describe the effectiveness and safety of P2Y12 receptor inhibitors in patients with STEMI based on the data from contemporary European ACS registries. Methods and results Twelve registries provided data in a systematic manner on outcomes in STEMI pati

γ 2‐MSH increases during graded exercise in healthy subjects : comparison with plasma catecholamines, neuropeptides, aldosterone and renin activity

Summary. To evaluate the possibility that the proopiomelanocortin (POMC)‐derived peptide γ2‐melanocyte stimulating hormone (γ2‐MSH) has a role in circulatory regulation in man we studied circulating levels of this peptide at three different stages of physical activity in 10 young healthy subjects. The results were compared to simultaneously measured plasma levels of catecholamines, neuropeptide Y,

Effects of endovascular cooling on infarct size in ST-segment elevation myocardial infarction : A patient-level pooled analysis from randomized trials

Objectives: This study sought to examine the relationship between temperature at reperfusion and infarct size. Background: Hypothermia consistently reduces infarct size when administered prior to reperfusion in animal studies, however, clinical results have been inconsistent. Methods: We performed a patient-level pooled analysis from six randomized control trials of endovascular cooling during pri

Smärtbedömning hos äldre personer med kommunikationssvårigheter – en utvärdering av den svenska versionen av Doloplus-2.

The aim of this study was to psychometrically test the Swedish version of the Doloplus-2 instrument for its use among older people. The Doloplus-2 instrument is a pain assessment tool that aims at measure pain among those who can not fully express their pain of various reasons. The instrument was tested in a sample consisting of 48 patients with cognitive impairment. Each patient was observed by t

När vården (be-)möter långvarig smärta

Ett bra bemötande är en grundförutsättning för en bra vård av såväl personermed långvarig smärta som de utan smärta. Dock är ett vanligt problem attpersoner med långvarig smärta ofta blir misstrodda och personer med långvarig smärta blir oftare illa bemötta än de utan smärta. Av de med långvarig smärta var det omkring en tredjedel som uppgav att de blivit illa bemötta som sökt vård för sin smärta.

KASAM-instrumentets utveckling och psychometriska egenskaper - en översikt.

The Sense of Coherence scale (SOC) is a widely used instrument in medical research as well as in other research areas. The Sense of Coherenceis assumed as a useful concept in assessing an individual’s orientation to life and internal strengths. However, despite the frequent use in vari-ous research studies and several psychometric evaluations there is no unequivocal evidence for its validity and r