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Liver Fat Content and Hepatic Insulin Sensitivity in Overweight Patients With Type 1 Diabetes

Objectives: Patients with type 1 diabetes mellitus (T1DM) lack the portal/peripheral insulin gradient, which might diminish insulin stimulation of hepatic lipogenesis and protect against development of nonalcoholic fatty liver disease (NAFLD). We compared liver fat content and insulin sensitivity of hepatic glucose production and lipolysis between overweight T1DM patients and nondiabetic subjects.

Konstnärer är inte mer kreativa än andra

Vi väntar oss att konstnärer ska vara kreativa, men erfarna konstnärer är framför allt hantverksskickliga. I allmänhet är konstnärer inte mer kreativa än andra människor. De kompletterar en tradition eller etablerad teoribildning, precis som forskare. Men till skillnad mot forskare som har ett väldefinierat problem med en given om än okänd lösning via en föreskriven metod, arbetar konstnären med ö

Beständiga förändringar av säkerhetskulturen

Säkerhet är dynamiskt och speciellt så i komplexa säkerhetskritiska verksamheter. När olyckor och incidenter är sällan förekommande i säkerhetskritiska verksamheter kan det ske en långsam och naturlig erosion av säkerhetsmedvetandet och en organisations beteenden kan börja driva mot säkerhetsmarginalerna. Säkerhetskulturen ses som en stark motriktad kraft i ett sådant händelseförlopp. Att organisa

Antisocial personality disorder as a predictor of criminal behaviour in a longitudinal study of a cohort of abusers of several classes of drugs: Relation to type of substance and type of crime.

Mixed findings have been made with regard to the long-term predictive validity of antisocial personality disorder (ASPD) on criminal behaviour in samples of substance abusers. A longitudinal record-linkage study of a cohort of 1052 drug abusers admitted 1977-1995 was undertaken. Subjects were recruited from a detoxification and short-term rehabilitation unit in Lund, Sweden, and followed through c

No title

The article provides with an overview over female sociability in eighteenth century Sweden.

Studies of ADAMTS13 expression and activity in the kidney

Von Willebrand factor (VWF) is an abundant plasma glycoprotein involved in platelet adhesion and aggregation at sites of vascular injury. ADAMTS13 is the sole physiological VWF-cleaving protease, thus regulating the size of thrombus growth. Dysfunctional ADAMTS13 leads to thrombotic thrombocytopenic purpura (TTP), which is either due to mutations (congenital TTP) or auto-antibodies (acquired TTP).

Free carrier absorption and inter-subband transitions in imperfect heterostructures

We present the results of a quantum mechanical modelling of the free carrier absorption (FCA) in semiconductor heterolayers. Elastic and inelastic scatterers are considered with emphasis on the interface defects (optical phonons) contributions to the induced photon absorption for elastic (inelastic) scatterers. Various approaches to FCA are also presented (perturbation, Green's function technique)

Neofunctionalization in an ancestral insect desaturase lineage led to rare Delta(6) pheromone signals in the Chinese tussah silkworm

The Chinese tussah silkworm, Antheraea pernyi (Lepidoptera: Saturniidae) produces a rare dienoic sex pheromone composed of (E,Z)-6,11-hexadecadienal, (E,Z)-6,11-hexadecadienyl acetate and (E,Z)-4,9-tetradecadienyl acetate, and for which the biosynthetic routes are yet unresolved. By means of gland composition analyses and in vivo labeling we evidenced that pheromone biosynthesis towards the immedi

Metal ion accessibility of histidine-modified superfolder green fluorescent protein expressed in Escherichia coli

Green fluorescent protein (GFP) is frequently utilized for metal ion detection and quantification. To improve the metal binding potential of GFP, three residues (N146, F165, and L201) were substituted to histidines. Each variant responded differently upon interaction with metal ions. More than 80% of N146H, having the most accessible surface area, could bind to immobilized metal ions. However, onl

Gestational diabetes mellitus among Nordic Caucasian women: Prevalence and risk factors according to WHO and simplified IADPSG criteria

Background. Gestational diabetes mellitus (GDM) is associated with both maternal and offspring adverse effects. The World Health Organization (WHO) has recently adopted novel GDM criteria. The aim of this study was to evaluate the former WHO and a simplified version of the new International Association for Diabetes in Pregnancy Study Group (IADPSG) criteria as to prevalence of and risk factors for

Redesigning a closed-loop supply chain exposed to risks

Supply chain management includes coordination and motivation of independently operating partners. Therefore, it is important to align logistics structures, processes and incentives, especially when making major changes involving those components. Traditionally, cost, quality, and service have served as prioritized performance indicators for supply chains, but lately risk is also taken into conside

Cosmetic buying behavior: examining the effective factors

This paper reports on the results of a cross-sectional study that focused on the impact of attitudes, subjective norms and consumer innovativeness on intention to purchase cosmetic products. Beginning with the Theory of Reasoned Action (Ajzen & Fishbein, 1980; Fishbein, 1980; Fishbein & Ajzen, 1975), several models have been proposed to conceptualize the complex behavioral and social proce

Electrical and Surface Properties of InAs/InSb Nanowires Cleaned by Atomic Hydrogen

We present a study of InAs/InSb heterostructured nanowires by X-ray photoemission spectroscopy (XPS), scanning tunneling microscopy (STM), and in-vacuum electrical measurements. Starting with pristine nanowires covered only by the native oxide formed through exposure to ambient air, we investigate the effect of atomic hydrogen cleaning on the surface chemistry and electrical performance. We find t