Age-related macular degeneration (AMD) is the most common cause of visual impairment in the developed world. A number of patients experience complex lifelike visual experiences—Charles Bonnet syndrome (CBS). In this systematic review, our aim was to provide an overview of the CBS literature in relation to AMD, to determine the prevalence of CBS in patients with AMD and to provide an overview of as

Objectives: We aimed to investigate the bone mineral density (BMD) in a group of Swedish patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) with or without asthma, as well as to evaluate whether the treatment of this patient group is in accordance with the EPOS recommendations. Design, settings and participants: Adult patients with a diagnosis of CRSwNP, and a history of at least t

Resistivity data constitute the largest part of the available information to assess the hydrogeological characteristics of the aquifer system near Oruro, in the central part of the Bolivian Altiplano. Two aquifers are part of this system; top unconsolidated sediments storing fresh water in their granular voids, overlying fractured hard rock formations where saline water was detected in connection

In partially premixed combustion engines high octane number fuels are injected into the cylinder during the late part of the compression cycle, giving the fuel and oxidizer enough time to mix into a desirable stratified mixture. If ignited by auto-ignition such a gas composition can react in a combustion mode dominated by ignition wave propagation. 3D-CFD modeling of such a combustion mode is chal

There is a growing interest in organized self-help housing (OSHH) from both authoriti es and Non Governmental Organizati ons (NGOs) working in the housing sector due to the magnitude of housing problems in developing countries and the challenge of achieving sustainable humansett lements. This paper focuses on the experiences of two NGOs, FUPROVI in Costa Rica and SADEL in Sweden, in facilitati ng

Objective: To describe the incidence of incorrect computerized ECG interpretations of atrial fibrillation or atrial flutter in a Swedish primary care population, the rate of correction of computer misinterpretations, and the consequences of misdiagnosis. Design: Retrospective expert re-analysis of ECGs with a computer-suggested diagnosis of atrial fibrillation or atrial flutter. Setting: Primary h

Focusing on artful, embodied listening as a method of analysing the emotional intensities of place, this article calls for academic geographers to listen to practitioners of nonacademic geography. It explores an ethical and methodological agenda for understanding how pop musicians have heard the world, and for taking them seriously as creative geographers who contribute sophisticated interpretatio

Understanding the etiology and meaning of behavioral symptomatology in the context of neurologic disease, and choosing the most effective intervention is a vexing task. This introduction summarizes the history of our understanding of the relationship between behavioral symptoms and primary neurologic conditions, and considers the ways in which both psychiatric and neurologic disorders occurring si

The epidermal growth factor system has been associated to prognosis in patients with bladder cancer based mainly on the expression of the epidermal growth factor (EGF) receptor 1 (EGFR) and HER2 and their activating ligands. Since limited information exists concerning the expression of other parts of the EGF system, we examined the expression of the receptors HER3 and HER4 and their activating lig

This dissertation explores the complexities of regional economic restructuring. It casts a light on how regional environments are ‘reconfigured’ in relation to the transformation of existing regional industries and the development of new ones. More specifically, the aim is to advance our understanding of regional innovation system (RIS) reconfiguration in relation to new regional industrial path d

The level of extracellular calcium has been demonstrated to regulate important physiological processes like cell growth and apoptosis. We demonstrate that in the bladder cancer cell line RT4, an increased extracellular calcium level induces apoptosis and that the HER1 receptor functions as a cell survival factor and delays apoptosis. After 12 h of calcium treatment (10 mM) apoptosis was detected i

Increased expression of the epidermal growth factor (EGF) receptors, HER1 and HER2 are related to poor prognosis in most cancers studied. Recently, a high expression of the two remaining receptors of the EGF system, HER3 and HER4 has been related to a favourable prognosis. However, prognostic significance of HER1 and HER2 receptors in bladder cancer is controversial and the effect of the expressio

Erfarenheterna från de amerikanska delstater som legaliserat cannabis visar att brottsligheten i princip inte påverkats alls. Forskningen visar också att insatser mot narkotikamarknaderna inte säkert skulle minska våldet. För att bekämpa gängvåldet bör insatserna i stället riktas mot våldet i sig, skriver forskarna Manne Gerell, Björn Johnson och Petter Karlsson.

What makes a business model successful? In this book the roots of business models are traced to the concept of the “business idea” which was popularized by researchers in the 1960s and 1970s. The business idea stresses the importance of conformance between the market and the product system, as well as between the product system and the internal features of the firm.A distinguishing feature of the

Most pathogens can infect a number of different host species, but host species often differ considerably in susceptibility to a given pathogen. In the case of zoonotic pathogens, natural hosts typically present little or no disease symptoms, while humans and other “spill-over” hosts often present severe symptoms. Differences in susceptibility do not only occur between natural and non-natural hosts