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The nursing programme in the rear-view mirror. Interviews with Swedish nurses one year after their graduation

In order to increase the understanding of how students assimilate the knowledge they need to carry out their professional duties, knowledge about the experience of the nursing education in the light of the first year of employment is important. The aim of this study was to describe nurses' views of their education, one year after their graduation. Interviews with eight nurses, aged 24 to 40 years,

Landlords' Experiences of Housing Tenants Suffering from Severe Mental Illness: A Swedish Empirical Study

The aim of this Swedish study was to describe landlords' experiences of having tenants suffering from severe mental illness. Sixteen landlords working in private and public housing agencies participated in open in-depth interviews. Data were subjected to a thematic latent content analysis. The results showed that having tenants with severe mental illness entails being confronted with various diffi

Precipitate evolution in the early stages of ageing in Inconel 718 investigated using small-angle x-ray scattering

Microstructural evolution during the early stages of ageing (less than one hour) in a Ni-Cr-Fe based superalloy Inconel 718 (IN718) has been investigated using Small-Angle X-ray Scattering (SAXS). The effects of precipitate kinetics on the precipitate size distribution are compared indirectly with SAXS measurements by using Vickers microhardness data. The microhardness increased after 4 min of age

An importance sampling technique for probabilistic security assessment in power systems with large amounts of wind power

Larger amounts of variable renewable energy sources bring about larger amounts of uncertainty in the form of forecast errors. When taking operational and planning decisions under uncertainty, a tradeoff between risk and costs must be made. Today's deterministic operational tools, such as N-1-based methods, cannot directly account for the underlying risk due to uncertainties. Instead, several defin

Spectral sensitivity in Onychophora (velvet worms) revealed by electroretinograms, phototactic behaviour and opsin gene expression.

Onychophorans typically possess a pair of simple eyes, inherited from the last common ancestor of Panarthropoda (Onychophora + Tardigrada + Arthropoda). These visual organs are thought to be homologous to the arthropod median ocelli, whereas the compound eyes most likely evolved in the arthropod lineage. To gain insights into the ancestral function and evolution of the visual system in panarthropo

Safety, tolerability, and antibody response of active A beta immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study

Background Immunotherapy targeting the amyloid beta (A beta) peptide is a potential strategy to slow the progression of Alzheimer's disease. We aimed to assess the safety and tolerability of CAD106, a novel active A beta immunotherapy for patients with Alzheimer's disease, designed to induce N-terminal A beta-specific antibodies without an A beta-specific T-cell response. Methods We did a phase 1,

A unique 3D endoanal ultrasound feature of perianal Crohn's fistula:the "Crohn ultrasound fistula sign" (CUFS).

Aim: Using a high-resolution 3D endoanal ultrasound, we have observed that some perianal fistulas show a hypoechogenic fistula tract surrounded by a well-defined hyperechogenic area with a thin hypoechogenic edge outside characterized fistulas in patients with Crohn's disease ("Crohn's Ultrasound Fistula Sign" (CUFS)), unlike conventional fistula tracks.. The study aimed to determine the prevalenc

Intratumoral COX-2 inhibition enhances GM-CSF immunotherapy against established mouse GL261 brain tumors.

Immunotherapy has shown effectiveness against experimental malignant brain tumors, but the clinical results have been less convincing most likely due to immunosuppression. Prostaglandin E2 (PGE2 ) is the key immunosuppressive product of cyclooxygenase-2 (COX-2) and increased levels of PGE2 and COX-2 have been shown in several tumor types including brain tumors. In the current study, we report enha

Wave propagation in birefringent materials with off-axis absorption or gain

The polarization direction of an electromagnetic field changes and eventually reaches a steady state when propagating through a birefringent material with off-axis absorption or gain. The steady state orientation direction depends on the magnitude of the absorption (gain) and the phase retardation rate. The change in the polarization direction is experimentally demonstrated in weakly doped (0.05%)

Talking work in a bank: A study of organizing properties of leadership in work interactions

Leadership is generally seen not only as an inspiring and motivating force but also as having important organizing properties. Despite this common assumption, the organizing properties of leadership have not yet been clarified sufficiently or demonstrated empirically. In this study, such organizing properties are revealed through a detailed analysis of one single work episode, drawn from an ethnog

A generalized birthday approach for efficiently finding linear relations in l-sequences

Feedback with carry shift registers (FCSRs) have previously been available in two configurations, the Fibonacci and Galois architectures. Recently, a generalized and unifying FCSR structure and theory was presented. The new ring FCSR model repairs some weaknesses of the older architectures. Most notably, the carry cell bias property that was exploited for an attack on the eSTREAM final portfolio c

Response of a free-flying songbird to an experimental shift of the light polarization pattern around sunset

The magnetic field, the sun, the stars and the polarization pattern of visible light during twilight are important cues for orientation in nocturnally migrating songbirds. As these cues change with time and location on Earth, the polarization pattern was put forward as a likely key reference system calibrating the other compass systems. Whether this applies generally to migratory birds is, however

Identification of plasticity constants from orthogonal cutting and inverse analysis

The aim of this work is that from experimental determined cutting process parameters be able to predict the plasticity input constants to Finite Element Method (FEM) models. In the present study the Johnson-Cook constitutive model constants are determined on the basis of cutting process parameters in orthogonal cutting and by use of inverse analysis. Previously established links between Johnson-Co

Let the drugs lead the way! : On the unfolding of a research programme in psychiatry

Following reports in the late 1950s of a correlation between the effects of psychotropic drugs on monoamine metabolism and on affective states, it became generally accepted that brain monoaminergic systems contributed to the pathophysiology of depression. After this, psychiatric researchers continued to pursue the neurochemical effects of antidepressants, hoping to gain novel insights into the bio