Introduction: The prognosis of patients at the pre-dementia stage is difficult to define. The aim of this study is to develop and validate a biomarker-based continuous model for predicting the individual cognitive level at any future moment. In addition to personalized prognosis, such a model could reduce trial sample size requirements by allowing inclusion of a homogenous patient population. Meth

Implementing energy efficiency measures in historic buildings is a challenging task and require knowledge in a number of different disciplines. The measures to reduce energy use must create a good indoor environment without jeopardizing the loss of important cultural historical values or entailing damages to building materials or load-bearing structures. Building antiquarian-, building biological-

The vascular effects of endogenous substances can be eas- ily studied in the skin. Early in this century vasoregulation was shown to be dependent on innervation. Peptidergic trans- mitters have been shown to coexist and cotransmit along with noradrenalin and acetylcholine, sometimes being responsi- ble for non-adrenergic-non-cholinergic responses. This review summarizes recent information on vasor

We have analysed hydrogen exchange at amide groups to characterise the energy landscape of the 72 amino acid residue protein MerP. From the guanidine hydrochloride (GuHCl) dependence of exchange in the pre-transitional region we have determined free energy values of exchange (ΔGHX) and corresponding m-values for individual amide protons. Detailed analysis of the exchange patterns indicates that fo

PurposeWear of ceramic orthopedic devices generates nanoparticles in vivo that may present a different biological character from the monolithic ceramic from which they are formed. The current work investigated protein adsorption from human plasma on alumina nanoparticles and monolithic samples representative of both wear particles and the ceramic components as implanted.Materials and MethodsA phys

Nanoparticles in a biological fluid (plasma, or otherwise) associate with a range of biopolymers, especially proteins, organized into the “protein corona” that is associated with the nanoparticle and continuously exchanging with the proteins in the environment. Methodologies to determine the corona and to understand its dependence on nanomaterial properties are likely to become important in bionan

Atherosclerotic cardiovascular disease (ACVD) is the leading cause of death worldwide. This study aimed to investigate the association between diet and lifestyle factors, beyond traditional risk factors, and the risk of incident ACVD. The Malmö Diet and Cancer study included 30,446 middle-aged individuals. Baseline examinations including a dietary assessment, questionnaire and interviews, were per

Pneumonia is a global cause of mortality, and this provides a strong incentive to improve the mechanistic understanding of innate immune responses in the lungs. Here, we characterized the involvement of the cytokine interleukin (IL)-26 in bacterial lung infection. We observed markedly increased concentrations of IL-26 in lower airway samples from patients with bacterial pneumonia and these correla

In this paper, a recently conducted measurement campaign for high-speed-train (HST) channels is introduced, where the downlink signals of an in-service Universal Mobile Terrestrial System (UMTS) deployed along an HST railway between Beijing and Shanghai were acquired. The channel impulse responses (CIRs) are extracted from the data received in the common pilot channels (CPICHs). Within 1318 km, 14

In parallel with the decrease in cost, size and weight of Unmanned Aerial Vehicles (UAVs) and the increase of their flight autonomy, many commercial applications are rapidly arising. Most of those applications rely on a communications system between a terrestrial base station and the UAV. Due to the UAV movement, time-variant channel models are required. In this article, we propose a geometrical m

Vector network analyzer (VNA) has been extensively utilized for radio channel sounding purposes. Due to its slow channel sounding speed, it has been mainly used for channel measurements in static propagation scenarios. The main limitation with VNA based channel sounder is its small measurement range, due to signal attenuation in the coaxial cable setup. Employing radio over fiber (RoF) can effecti

We demonstrate that finite impulse response (FIR) models can be applied to analyze the time evolution of an epidemic with its impact on deaths and healthcare strain. Using time series data for COVID-19-related cases, ICU admissions and deaths from Sweden, the FIR model gives a consistent epidemiological trajectory for a simple delta filter function. This results in a consistent scaling between the

It is unknown if the lung deposition of surfactant administered via a catheter placed through a laryngeal mask airway (LMA) is equivalent to that obtained by bolus instillation through an endotracheal tube. We compare the lung deposition of surfactant delivered via two types of LMA with the standard technique of endotracheal instillation. 25 newborn piglets on continuous positive airway pressure s

Updated information on child feeding practices, nutritional status, and trends related to parental sociodemographic variables is required in developing countries. The objective of this study was to describe infant feeding practices and associated sociodemographic factors among Ethiopian children with an emphasis on complementary feeding (CF). Information on infant feeding and anthropometric measur

The confidentiality and integrity algorithms in cellular networks protect the transmission of user and signaling data over the air between users and the network, e.g., the base stations. There are three standardised cryptographic suites for confidentiality and integrity protection in 4G, which are based on the AES, SNOW 3G, and ZUC primitives, respectively. These primitives are used for providing

Recently, a measurement campaign for characterizing the channels in underground subway environments was conducted in Shanghai, China. Downlink signals transmitted by 46 universal mobile telecommunication system cells deployed along a 34-km-long subway were collected. Channel impulse responses are extracted from the data received in the common pilot channels, based on which parameters of multipath

In this paper, a measurement campaign in high-speed-train (HST) environments is introduced where the downlink signals of an in-service Universal Mobile Terrestrial System (UMTS) deployed along a HST railway between Beijing and Shanghai were required by a single receiving antenna. Channel Impulse Responses (CIRs) are extracted from the data received in Common PIlot CHannels (CPICHs). The train spee

Unmanned Aerial Vehicles (UAVs) have been widely used in military and civilian fields in the recent years. In order to give support to the vast amount of added value services, UAV communications have become a hot spot for the fifth generation (5G) and have a very broad development prospect. In this paper, based on the channel modeling results obtained by actual measurements, we evaluate the end-to