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The enzyme dUTPase catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate, thereby preventing a deleterious incorporation of uracil into DNA. The best known dUTPase is that from Escherichia coli, which, like the human enzyme, consists of three identical subunits. In the present work, the catalytic properties of the E. coli dUTPase were investigated in the pH range 5-11. The enzyme was found to
The increasing test data volume needed to test core-based System-on-Chip contributes to long test application times (TAT) and huge automatic test equipment (ATE) memory requirements. TAT and ATE memory requirement can be reduced by test architecture design, test scheduling, sharing the same tests among several cores, and test data compression. We propose, in contrast to previous work that addresse
This paper presents a phase noise analysis of the very popular differential LC-tank CMOS oscillator. Closed-forms formulas for the phase noise in the 1/f2 region are derived under very general assumptions.
By means of a myograph, postjunctional alpha-adrenoceptors were characterized in human superficial epigastric arteries and veins obtained from health subjects. The rank order of potency of subtype selective agonists could not be used for receptor characterization in these vessels, whereas antagonists gave distinct results. It was found that the arteries were endowed mainly by alph1-adrenoceptors b
Popular Abstract in Swedish Avhandlingens huvudsyfte är att försöka utreda hur man kommer till förståelse av det historiska huset och att diskutera vilken roll den historiska dokumentationen spelar i restaureringsprojekteringen. I restaurering som i allt annat arbete med arkitektur är förståelse ett nyckelord. Förståelse för de särskilda förutsättningar som ligger i uppgiften, i objektet, i skapanThe principal aim of the thesis is to evaluate the significance of the documentation of a building’s history for the work of restoring it and caring for it. Thus it may be said to address restoration as a hermeneutical problem, besides considering the relationships between the work of documentation; analyses of the resulting data; and the creative process in which the ideology of restoration is im
In this work, we present a method for estimating the parameters detailing an unknown number of linear chirp signals, using an iterative sparse reconstruction framework. The proposed method is initiated by a re-weighted Lasso approach, and then use an iterative relaxation-based refining step to allow for high resolution estimates. The resulting estimates are found to be statistically efficient, ach
Popular Abstract in Swedish Vakuum-assisterad sårläkning (VAC) är en relativt ny metod för att påskynda sårläkning där primär läkning av ett eller annat skäl inte skett. Inom hjärtkirurgin anses mediastiniten, en sårinfektion som uppstår i operationsorådet kring bröstbenet efter kirurgi, vara en av de tre mest allvarliga postoperativa komplikationerna. Trots att hjärtkirurgi nu även erbjudes till Poststernotomy mediastinitis is a devastating complication associated with median sternotomy, which occurs mainly after cardiac surgery. The optimal treatment is still controversial. The aim was to develop, describe and evaluate a surgical procedure consisting of vacuum-assisted closure (VAC) in combination with delayed primary closure in patients with mediastinitis. A porcine sternotomy wound mo
Cellulose can be chemically modified to produce derivatives with specific properties. Knowledge of correlations between the modification reaction, substituent distribution, origin of cellulose and properties are importaint in order to design processess so as to produce derivatives with the desired properties. This thesis describes research on newly developed analytical methods for the analysis of
Popular Abstract in Swedish Djurs förmåga att hitta då de förflyttar sig långa sträckor mellan fortplantningsområden och övervintringsområden har fascinerat människor i hundratals år. Det finns flera olika teorier kring hur djur navigerar, till exempel med hjälp av dofter, landmärken, solen, polariserat ljus, stjärnorna eller jordens magnetfält. Att djur skulle kunna använda sig av just jordens maMigration research is a large and diverse field and in my thesis I have focused on the impact of geomagnetic cues on animal orientation, navigation and migratory fuelling. Several animal species from widely different taxa possess the ability to sense and make use of geomagnetic information during migratory or homing events. I used a map showing isolines for magnetic total field intensity and incl
