Terephthalate polyesters such as poly(ethylene terephthalate) (PET) have been massively produced over the last few decades due to their attractive properties in multiple applications. However, due to their limited biodegradability, they have accumulated in landfills and oceans, posing an environmental threat. Enzymatic recycling technologies are predicted to generate long-term socioeconomic benefi

BACKGROUND: Poor adherence to antiretroviral therapy in adolescents living with HIV is a global challenge. One of the key strategies to improve adherence is believed to be the use of digital adherence tools. However, evidence is limited in this area. Our objective was to investigate the effectiveness of mobile phone text message reminders in improving ART adherence for adolescents.METHODS: The pre

Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. In gardens, vitality is often regarded as an asset and a reason to cultivate certain plants. Many varieties that have spread over centuries are today regarded as ‘belonging’, as more or less ‘natural’, and even as heritage plants. Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. In gardens, vitality is often regarded as an asset and a reason to cultivate certain plants. Many varieties that have spread over centuries are today regarded as ‘belonging’, as more or less ‘natural’, and even as heritage plants.

Background: Guidelines regarding whether tamoxifen should be prescribed based on women's cytochrome P450 2D6 (CYP2D6) genotypes are conflicting and have caused confusion. This study aims to investigate if CYP2D6 metabolizer status isa associated with tamoxifen-related endocrine symptoms, tamoxifen discontinuation, and mammographic density change. Patients and methods: We used data from 1440 health

Eulerian stochastic fields (ESF) based transported PDF method has evolved as one of the general purpose methods for the numerical simulation of complex chemically reactive turbulent flows in which the effect of turbulence on the chemical reaction rates can be computed directly without the need of modeling. It is found that ESF method may suffer from violation of the element mass conservation law d

BACKGROUND: Recent whole genome sequencing studies report that up to 6% of the childhood cancer population harbour a pathogenic variant. Identification of families with hereditary cancer may improve early detection of cancer as well as treatment outcome. AIMS: The overall aim of this thesis was to investigate familial cancer risk in relatives of children with cancer and assess the prevalence of pa

Asthma exacerbations are commonly triggered by rhinovirus infections. Viruses can activate the NFκB pathway resulting in airway inflammation and increased Th2 cytokine expression. NFκB signaling is also involved in early activation of IFNβ, which is a central mediator of antiviral responses to rhinovirus infection. Using a mouse model, this study tests our hypothesis that NFκB signaling is involve

Background: The impact of adrenalectomy on morbidity in patients with mild hypercortisolism and non-functioning adrenocortical adenoma is unclear. The present study evaluated morbidity before and after adrenalectomy in patients with benign adrenocortical tumour with Cushing´s syndrome (CS), autonomous cortisol secretion (ACS) and non-functioning adrenocortical adenoma as assessed by national and q

A common library, TMDlib2, for Transverse-Momentum-Dependent distributions (TMDs) and unintegrated parton distributions (uPDFs) is described, which allows for easy access of commonly used TMDs and uPDFs, providing a three-dimensional (3D) picture of the partonic structure of hadrons. The tool TMDplotter allows for web-based plotting of distributions implemented in TMDlib2, together with collinear

Purpose: To highlight recognizable patterns of subretinal fibrosis in enhanced S-cone syndrome (ESCS). Design: Retrospective case series. Participants: Forty-seven patients with subretinal fibrosis identified from 101 patients with clinically diagnosed ESCS, confirmed by full-field electroretinography (35/47), genetic testing (34/47), or both. Methods: Multimodal retinal imaging, electroretinograp

This work considers direction-finding using a monostatic multiple-input multiple-output (MIMO) radar in the presence of impulsive noise. Employing a novel low-order covariance-based exponential kernel function, the proposed maximum likelihood (ML) formulation exploits an introduced quantum whale optimization algorithm (QWOA) to form the direction estimates. The resulting estimates are shown to be

Objectives This study aimed to explore the relationship (presence and severity) between chronic breathlessness and sleep problems, independently of diagnoses and health service contact by surveying a large, representative sample of the general population. Setting Analysis of the 2017 South Australian Health Omnibus Survey, an annual, cross-sectional, face-to-face, multistage, clustered area system

The agri-food sector and supply chain is a foundational component of society and is required for healthy populations across the globe. Feeding the world, not only with enough calories, but with nutritious food that has been sustainably sourced and processed, is a continuous and developing challenge. Despite this, careers in research and development opportunities in the agri-food sector have less v

Population bottlenecks associated with founder events strongly impact the establishment and genetic makeup of populations. In addition to their genotype, founding individuals also bring along parasites, as well as symbionts that can manipulate the phenotype of their host, affecting the host population establishment, dynamics and evolution. Thus, to understand introduction, invasion, and spread, we