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Avhandlingsskrivande och val av forskningsansats : en idé om rättsvetenskaplig öppenhet
Review of analytical methods for measurement of oat proteins : The need for standardized methods
This review summarizes the analytical methods that have been developed for quantification and characterization of oat proteins. These include sampling, sample preparation, extraction, quantification, separation, detection, and characterization of oat proteins. The review also provides a comparison of different methods for the determination of protein fraction of oat and the efficiency thereof. We
New spectroscopic information on 211,213Tl : A changing structure beyond the N=126 shell closure
The neutron-rich isotopes 211,213Tl, beyond the N=126 shell closure, have been studied for the first time in isomer γ-ray decay, exploiting the fragmentation of a primary uranium beam at the Fragment Separator-Rare Isotopes Investigation at GSI setup. The observed isomeric states in 211,213Tl show a deviation from the seniority-like scheme of 209Tl. The possible interpretation of the data is discu
MRI morphology of the hippocampus in drug-resistant temporal lobe epilepsy: shape inflation of left hippocampus and correlation of right-sided hippocampal volume and shape with visuospatial function in patients with right-sided TLE
We sought to quantify the morphology in vivo of hippocampi in patients with drug resistant temporal lobe epilepsy (TLE) via magnetic resonance imaging (MRI), prior to temporal lobe resection, and the correlation of surface-based shape analysis of morphology and clinical cognitive function.Thirty patients with drug-resistant TLE and twenty healthy controls underwent clinical neuropsychological test
Worldwide comparison of survival from childhood leukaemia for 1995-2009, by subtype, age, and sex (CONCORD-2) : a population-based study of individual data for 89 828 children from 198 registries in 53 countries
BACKGROUND: Global inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme was designed to assess worldwide differences and trends in population-based cancer survival. In this population-based study, we aimed to estimate survival inequalities globally for several subtypes of childhood leukaemia.METHODS: Cancer registries participating in CONCORD
Socialt arbete - vetenskap.
Associations between occupational and social interaction factors and well-being among people with psychiatric disabilities living in supported housing in Sweden
Research indicates that occupation is important for well-being in people with mental illness, but this has not been extensively studied among those with severe psychiatric disabilities. Social contacts may possibly play a more vital role for them. This study aimed to explore how aspects of occupation and social interaction were related with well-being factors in that group, while controlling for t
Hazardous Substance Use among People with Psychiatric Disabilities Visiting Day Centers
Objective: People who suffer from psychiatric illness have a more than doubled lifetime risk of acquiring an alcohol or drug use disorder. Furthermore, hazardous substance use impairs treatment outcomes and protracts the duration of illness among people with mental disorders. The aim of this study was to investigate substance use among people with psychiatric disabilities receiving municipality-ba
Value of a QALY and VSI estimated with the chained approach
The value of a quality-adjusted life-year (QALY) and the value of a statistical injury (VSI) are important measures within health economics and transport economics. Several studies have, therefore, estimated people's willingness to pay (WTP) for these estimates, but most results show scale insensitivity. The 'original' chained approach (CA) is a method developed to mitigate this problem by combini
Feasible Coordination of Multiple Homogeneous or Heterogeneous Mobile Vehicles with Various Constraints
We consider the problem of feasible coordination control for multiple homogeneous or heterogeneous mobile vehicles subject to various constraints (nonholonomic motion constraints, holonomic coordination constraints, equality/inequality constraints etc). We develop a general framework involving differential-algebraic equations and viability theory to describe and determine coordination feasibility
Fermented milk products are associated to ulcer disease. Results from a cross-sectional population study
Background: Prevalence of peptic ulcer disease has been associated to diet. Some dietary factors seem to have bactericidal effect which may modify the risk of peptic ulcer disease. The objective was to analyze associations between dietary habits and peptic ulcers. Design: A cross sectional population study. Subjects: One thousand, one hundred and thirty-five subjects out of 11,700 randomly invited
How should a group living unit for demented elderly be designed to decrease psychiatric symptoms?
The main objectives were to study relationships between the design of group living (GL) units and psychiatric symptoms in demented patients before, 6 months after, and 1 year after admission to GL units. The study population comprised 105 demented elderly (83 ± 6 years), 37% with dementia of Alzheimer's type and 58% with vascular dementia. The patients were relocated by the municipal care planning
Optimised expression and purification of recombinant human indoleamine 2,3-dioxygenase
The hemoprotein indoleamine 2,3-dioxygenase (IDO) is the first and rate-limiting enzyme in mammalian tryptophan metabolism. It has received considerable attention in recent years, particularly due to its role in the pathogenesis of many diseases. Here, we report attempts to improve soluble expression and purification of hexahistidyl-tagged recombinant human IDO from Escherichia coli (EC538, pREP4,
Recension av Sundqvist, O. & Vikstrand, P. (red.), Gamla Uppsala i ny belysning
Impact of donor chest radiography on clinical outcome after lung transplantation
BackgroundOrgan donation guidelines recommend a “clear” conventional bedside chest radiograph before lung transplantation despite only moderate accuracy for cardiopulmonary abnormalities.PurposeTo evaluate the influence of donor image interpretation on lung transplantation outcome in recipients by following early and late complications, one-year survival, and to correlate imaging findings and bloo
P-fimbriae trigger mucosal responses to Escherichia coli in the human urinary tract
Uropathogenic Escherichia coli elicit a host response that determines the severity of urinary tract infection (UTI). Specific adherence mechanisms allow the bacteria to initiate this process by targeting epithelial cells in the urinary tract mucosa. Epidemiological studies show a strong association of P-fimbriae with disease severity, suggesting that adherence mediated by these organelles has a di
Urodynamic factors influence the duration of Escherichia coli bacteriuria in deliberately colonized cases
Purpose: We evaluated the influence of urodynamic factors on the establishment of bacteriuria, after deliberate intravesical inoculation with Escherichia coli. Materials and Methods: Nine women and 7 men with recurrent symptomatic urinary tract infections underwent intravesical injection of E. coli 83972. This strain had documented ability to persist in the urinary tract and it lacks expressed vir
Competetive microbial exclusion as treatment against complicated lower urinary tract infections
OBJECTIVE: Deliberate colonization of the lower urinary tract has been proposed as treatment against recurrent urinary tract infection - UTI. The bacteria chosen has to be able to colonize the urinary tract for longer periods without causing symptoms, and should be able to prevent manifest superinfections. MATERIALS: Sixteen patients (9 women and 7 males), all having a history of recurrent symptom