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Blood pressure and risk of cancer in the European Prospective Investigation into Cancer and Nutrition

Several studies have reported associations of hypertension with cancer, but not all results were conclusive. We examined the association of systolic (SBP) and diastolic (DBP) blood pressure with the development of incident cancer at all anatomical sites in the European Prospective Investigation into Cancer and Nutrition (EPIC). Hazard ratios (HRs) (95% confidence intervals) were estimated using mu

Biofilm structure - An important and neglected parameter in waste water treatment

Experimental investigations on the kinetics of wastewater treatment processes in biofilms were performed in a laboratory reactor. Parallel with the kinetic experiments, the influence of the biofilm kinetics on the biofilm structure was studied at macroscopic and microscopic levels. The close interrelationship between biofilm kinetics and structural changes caused by the kinetics is illustrated by

Doping of GaAsP nanowires grown by aerotaxy

Nanowire (NW) Photovoltaics are a promising route for low-cost multi-bandgap tandem cells, which is taxing in terms of processing and lattice matching in traditional planar geometries.[1] III-V nanowires are more suitable for monolithic integration as they can assimilate the lattice mismatch to a larger extent.[2] GaAsP is a material that offers a wide tunability of the band gap from near infrared

Temperature optimization in district heating systems

Generally, low temperatures are favourable for district heating (DH) systems, while several factors limit how low temperatures can actually be. The history of DH is characterized by a constant strive for lower temperatures. In order to stay competitive, and increase its market share, the DH industry must continue the work towards even lower temperatures. This chapter goes through the impressive re

The Mini-Organo : A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development

Background: The use of in vitro cell cultures is a powerful tool for obtaining key insights into the behaviour and response of cells to interventions in normal and disease situations. Unlike in vivo settings, in vitro experiments allow a fine-tuned control of a range of microenvironmental elements independently within an isolated setting. The recent expansion in the use of three-dimensional (3D) i

The single state alternative in Palestine/Israel

Since the Oslo Accords, the two-state solution has dominated, and frustrated, the official search for peace in Palestine/Israel. In parallel to it, an alternative struggle of resistance—centred upon the single-state idea as a more liberating pathway towards justice to the conflict—has re-emerged against the hegemony of Zionism and the demise of a viable two-state solution in Palestine/Israel. This

Endoscopic submucosal dissection of malignant non-pedunculated colorectal lesions

Background and study aimsEndoscopic submucosal dissection (ESD) is an established method for en bloc resection of large non-pedunculated colorectal lesions in Asia but dissemination of ESD in Western countries is limited. The aim of this study was to evaluate the role of ESD in the management of malignant non-pedunculated colorectal lesions in a European center.Patients and methods Among 255 patie

The Revival of Agriculture and Inclusive Growth during the Commodity Boom in Latin America?

Latin America has constituted a recent example of inclusive growth by reducing poverty and income inequality simultaneously during the latest commodity boom. Against the backdrop of non-inclusive and non-transformative nature of commodity booms, we ask whether growth of agriculture was able to speed up structural transformation, and, relatedly, if agricultural growth was inclusive. We examine 16 c

Stockholmare, flytta dit bostäderna finns

På samma sätt som det är naturligt för ungdomar från bruksorter att flytta till Stockholm bör Stockholmsungdomar ställa in sig på att flytta ut från stan, skriver Ingemar Bengtsson, universitetslektor i fastighetsvetenskap vid Lunds universitet.

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On the Structure of Solid Lipid Nanoparticles

Solid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their ability to store and release organic molecules can be tailored through the identity of the lipids and surfactants used. When stored, polymorphic transitions in the core of drug-loaded SLNs lead to the prematur

Protein Dimensions and Interactions at Immune-Cell Contacts

Immune cells, such as B and T cells, fight pathogens infecting the human body. To fulfil this function the immune cells need to form a contact during which different membrane proteins play an important role. A key event in this contact is the interaction between the T-cell receptor (TCR) and an antigenic peptide-presenting major histocompatibility complex (MHC) protein. If this interaction is suff

Understanding the complexity of socioeconomic disparities in type 2 diabetes risk: A study of 4.3 million people in Sweden

Objective Investigating demographic and socioeconomic factors as intersecting rather than as separate dimensions may improve our understanding of the heterogeneous distribution of type 2 diabetes in the population. However, this complexity has scarcely been investigated and we still do not know the accuracy of these factors for predicting type 2 diabetes. Improved understanding of the demographic

Aggregation of value judgments differs from aggregation of preferences

My focus is on aggregation of individual value rankings of alternatives to a collective value ranking. This is compared with aggregation o individual prefrences to a collective preference. While in an individual preference ranking the alternatives are ordered in accordance with one’s preferences, the order in a value ranking expresses one’s comparative evaluation of the alternatives, from the best

Multiparametric real-time sensing of cytosolic physiology links hypoxia responses to mitochondrial electron transport

Hypoxia regularly occurs during plant development and can be induced by the environment through, for example, flooding. To understand how plant tissue physiology responds to progressing oxygen restriction, we aimed to monitor subcellular physiology in real time and in vivo. We establish a fluorescent protein sensor-based system for multiparametric monitoring of dynamic changes in subcellular physi