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Proteiner är några av livets beståndsdelar. Komplexa molekyler som förser våra kropparmed både struktur och funktion, bland annat i muskler. De är kedjor av aminosyror,som vartefter de skapas i kroppen ofta veckar sig till en specifik tredimensionell strukturför att kunna utföra den funktion de har optimerats för under evolutionens gång.Uppstår fel i denna process kan felaktiga strukturer, som oftA protein chain often folds into a functional, specific three dimensional structure. Failurein this process can in some cases lead to disease, e.g. the misfolding disease ALS. Themechanisms behind the folding has mostly been studied under dilute conditions. However,in the natural cellular environment of proteins, the concentration of macromolecules is highand it is believed that this affects vario

OBJECTIVE: To evaluate the measurement variability of quantitative sensory testing (QST) in persons with post-stroke shoulder pain. DESIGN: A test-retest design. PARTICIPANTS: Twenty-three persons with post-stroke shoulder pain (median age 65 years).METHODS: Thermal detection thresholds (cold and warm), pain thresholds (cold and heat) and mechanical pain thresholds (pressure and pin prick) were as

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A number of biological systems have been studied in the past in an attempt to find the underlying cause of anxiety and depression. The main aim of the work described in this thesis was to investigate the importance of inflammation and the renin-angiotensin-aldosterone system (RAAS) in relation to anxiety and depression. The methods used ranged from studying patients to preclinical animal experimen

Polyelectrolyte adsorption and polymer mediated interactions in different colloidal polymer systems have been studied in this work. Theoretical methods and experimental techniques are combined, in order to obtain more general reliable results, as well as a deep understanding of the molecular mechanisms that are responsible for the observed behaviors. Two different types of highly charged cationic

Zero Magic is a trick for the financial markets, which has the capacity to undermine the perceived value of a publicly traded company and profit from this. Short selling is a way of profiting from loss: Making money if and when a target company loses in value. It is a fundamental market activity that goes as far back as the first stock, yet to this day little is publicly known about the strategie

Transition to adulthood, referring to the process of moving from childhood to adulthood, can be a complex period for youths with disabilities who might need special support transitioning into an independent life as adults. Caregivers are significant persons for the youths, which is why their own health and wellbeing is important. Therefore the overall aim of this thesis was to gain a deeper unders

Popular Abstract in English Soil as an ecosystem is a reservoir for several living organisms including microorganisms, earthworms, collembolans, nematodes and protozoans. They are involved in cycling the nutrients through degrading the organic compounds (source of carbon essential for all living organisms) like plant residues and respire part of it as carbon dioxide. Organic compounds get stored iAbstract Intensive land use in agriculture can lead to higher loss of biodiversity in soils and subsequently carbon due to tillage and application of pesticides and fertilizers. The microbial communities are pivotal to ecosystem processes in soil such as nutrient cycling, soil formation and plant productivity and thus are affected by land use. The main aim of this thesis is to understand the effe

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The aim of the thesis The Court Service in Sweden. Regulation and Development 1684-1989 is to investigate the special church service which was decreed by Swedish law in connection with trials in law courts between 1684 and 1989. The service was initiated by King Karl XI of Sweden in 1684 by a letter to the Bishop of Västerås Diocese. Initially, the service was held only within parts of the Dioces

The protective effect of most currently available vaccines is dependent on high-affinity antibodies and long lived B cell memory, which develop within organized structures of secondary lymphoid organs called germinal centers (GCs). GC formation is supported by T follicular helper (Tfh) cells, a subset of CD4+ T cells that develop in parallel to other effector T cells and specifically localizes to

Since the Ukraine conflict began in 2014, there has been an increased awareness of the threat to EU interests posed by Russia. In early 2015, the EEAS created the East StratCom Team to respond by promoting the EU’s soft power, strengthen media resilience, and catalogue disinformation. This article categorizes several examples of Russian disinformation in order to conceptualize the conduct of digit

In this thesis I focus on soundpainting-mediated musical experiences. Proposed in the mid seventies by the American musician Walter Thompson (b. 1952), soundpainting is a conventionalized artistic practice designed to create artistic works in real time. Thompson’s definition of soundpainting as a sign language is central to the present artistic inquiry, based on different moments of artistic pract

OBJECTIVE: To determine prevalence and intensity of pain after stroke, focusing on patients' perspectives. METHODS: During a one year period, 416 first-ever stroke patients were included in the population based Lund Stroke Register. After 4 and 16 months (median), 297 patients (98% of survivors) were followed up. Worst pain intensity during the previous 48 hours was assessed on a visual analo

Body temperature (Tb) is a valuable parameter when assessing the physiological state of animals, but its widespread measurement is often constrained by methods that are invasive or require frequent recapture of animals. Alternatives based on automated remote sensing of peripheral Tb show promise, but little is known about their strengths and limitations. We measured peripheral Tb in great tits Par

This thesis is consists of two parts, applying concepts from automatic control to different application areas.The first part of this thesis concerns the development of an optimization-based algorithm, determining the size of insulin and glucose doses for patients suffering from Diabetes Mellitus and treated with multiple insulin injections. Diabetes Mellitus is a chronic disease characterized by eThis thesis consists of two parts, applying concepts from automatic control to different application areas.The first part of this thesis concerns the development of an optimization-based algorithm, determining the size of insulin and glucose doses for patients suffering from Diabetes Mellitus and treated with multiple insulin injections. Diabetes Mellitus is a chronic disease characterized by elev

Several severe fires in structural elements, or so-called “structural fires”, have occurred in Sweden in recent years. In order to study this phenomenon, a dozen of real fires in structural elements have been studied in this report. The first objective in the report has been to define the term “structural fires”. The second objective was to describe how these severe fires start and developed. The

Methods for determination of indoor noise and vibrations from urban rail bound transport are presented in this work. Both measurement methods and empirical prediction methods are described. The data and results are taken from field measurements of noise and vibrations from the trams and metro trains of Oslo.The methods applied should be universally adaptable. The general approach is to use empiric

In this work we present the quasi-steady state simulation of a regenerative organic Rankine cycle (ORC) integrated in a passenger vessel, over a standard round trip. The study case is the M/S Birka Stockholm cruise ship, which covers a daily route between Stockholm (Sweden) and Mariehamn (Finland). Experimental data of the exhaust gas temperatures, engine loads, and electricity demand on board wer