Background: Inflammation acting in synergy with brain ischemia aggravates perinatal ischemic brain damage. The sensitizing effect of pro-inflammatory exposure prior to hypoxia is dependent on signaling by TNF-alpha through TNF receptor (TNFR) 1. Adrenoceptor (AR) activation is known to modulate the immune response and synaptic transmission. The possible protective effect of (alpha) over tilde and

Ebba Ossiannilsson Lunds universitet Alastair Creelman, Linnéuniversitetet OER, MOOC, spelifiering och badgerörelsen Det är bara några av de trender vi har sett under 2012, mer kommer det att bli framöver och fort går det runt om i världen. I Horizon rapporten för 2012 förutsågs detta, men även augmented learning, individualiserat lärande, kursdesign och examination för lärande, sociala medier, le

Codes constructed from connected spatially coupled low-density parity-check code (SC-LDPCC) chains are proposed and analyzed. It is demonstrated that connecting coupled chains results in improved iterative decoding performance. The constructed protograph ensembles have better iterative decoding thresholds compared to an individual SC-LDPCC chain and require less computational complexity per bit wh

The genetic networks controlling stem cell identity are the focus of intense interest, due to their obvious therapeutic potential as well as exceptional relevance to models of early development. Genome-wide mapping of transcriptional networks in mouse embryonic stem cells (mESCs) reveals that many endogenous noncoding RNA molecules, including long noncoding RNAs (lncRNAs), may play a role in contr

Artikeln diskuterar moderniteten, samtiden, sociologin och förhållandet dem emellan samt hur samtiden betingar vetandet om denna samtid, och hur vetandet om samtiden gestaltas. Den epistemologiska konstellation som framkallas förstår jag som sociologisk samtidshermeneutik, eller samtidshermeneutisk sociologi. Dess grundantagande är: ju mer en kultur karakteriseras av kontingens (komplexitet, trans

OBJECTIVE- We studied differences between patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes, and classical type 1 diabetes diagnosed after age 35 years. RESEARCH DESIGN AND METHODS- Polymorphisms in HLA-DQB1, INS, PTPN22, and CTLA4 were genotyped in patients with LADA (n = 213), type 1 diabetes diagnosed at >35 years of age (T1D(>35y); n = 257) or 35y) and type 2 diabetic

To investigate if the Swedish entry rules for pets to prevent the introduction of Echinococcus multilocularis (EM) are proportional (i.e. that their costs do not exceed the value of their benefits), a dichotomous-choice contingent valuation study was conducted. The study was performed before the first case of EM was detected in Sweden in February 2011. About 5000, randomly selected, Swedish citize

This paper describes the fabrication and initial characterization of an ultra-thin silicon PIN detector using a new technique in silicon nanotechnology. In collaboration with the Nuclear Physics Division and the Lund Nano Lab at Lund University, we have developed and manufactured ultra thin Delta E-detectors for spectroscopic applications. The fabrication process has been carried out using a doubl

A review was performed of eight previously performed investigations of environmental impacts from end-consumer food waste prevention. The overall aim of the study was to investigate the state of the art in these assessments, identify key factors which could explain seen variations in GWP-emission savings, and suggest methodological improvements leading to increased potentials for cross-study compa

Background: Despite an extensive literature on treatment interventions for patients with knee osteoarthritis, studies comparing the efficacy of different exercise interventions and living the life as usual on quality of life, cartilage quality and cost-effectiveness are lacking. The aim of the present study is to compare the efficacy of two different exercise programs compared to a control group i

Background: Body size has been hypothesized to influence the risk of prostate cancer; however, most epidemiologic studies have relied on body mass index (BMI) to assess adiposity, whereas only a few studies have examined whether body fat distribution predicts prostate cancer. Methods: We examined the association of height, BMI, waist and hip circumference, and waist-hip ratio with prostate cancer

The low-lying structures of the self-conjugate (N = Z) nuclei Nb-82(41)41 and Tc-86(43)43 have been investigated using isomeric-decay spectroscopy following the projectile fragmentation of a Ag-107 beam. These represent the heaviest odd-odd N = Z nuclei in which internal decays have been identified to date. The resulting level schemes shed light on the shape evolution along the N = Z line between

We demonstrate single nanowire tunnel diodes with room temperature peak current densities of up to 329 A/cm(2). Despite the large surface to volume ratio of the type-II InP-GaAs axial heterostructure nanowires, we measure peak to valley current ratios (PVCR) of up to 8.2 at room temperature and 27.6 at liquid helium temperature. These sub-100-nm-diameter structures are promising components for sol

Abstract in UndeterminedPurpose - The purpose of this paper is to show that organizational change depends on societal narratives - narratives about the character, history, or envisioned future of societies. Design/methodology/approach - A case study of a Swedish municipal waste management company serves as an illustration. Findings - Swedish waste governance is powered by two main narratives: "les

This work aimed at evaluate diagnosis and prognosis in soft tissue sarcoma (STS): In study I, 32K bacterial artificial chromosome (BAC) arrays and gene expression profiling were applied to 18 leiomyosarcomas and 31 undifferentiated pleomorphic sarcomas (UPS), with the aim of identifying molecular subtype signatures. Both the gains/losses profiles and the gene expression signatures revealed strikin

In this paper the impact of different meals and rapid insulin were estimated as Finite Impulse Response Models from a data set of 18 patients. Based on these models short-term individualized predictors were tested for 20 and 60 minute prediction. The predictors were evaluated using Clarke Grid Analysis and had on average more than 94 % and 75 % in the A zone and less than 1 % and 3 % in the erroro

Introduction Musculoskeletal disorders (MSD) are nowadays seen within a biopsychosocial framework, including salutogenic factors, motivation factors, and coping ability. Such a framework recognizes the importance of motivational factors in health promotion and in rehabilitation. The Motivation for Change Questionnaire (MCQ) has been developed to measure the strength of individuals' motivation for

Aims: Previous studies have shown that membranous expression of podocalyxin-like protein (PODXL) is associated with poor prognosis in colorectal cancer (CRC). In this study, we compared PODXL expression in primary CRC and synchronous lymph node metastases. We further analyzed whether its expression changed in rectal tumours after neoadjuvant radiation therapy. Methods and results: The studied coho