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Field observations and experimental data of effects of nitrogen (N) deposition oil plant species diversity have been Used to derive empirical critical N loads for various ecosystems. The great advantage of such an approach is the inclusion of field evidence, but there are also restrictions, such as the absence of explicit criteria regarding significant effects on the vegetation, and the impossibil

We consider the diffractive Drell-Yan process in proton-(anti) proton collisions at high energies in the color dipole approach. The calculations are performed at forward rapidities of the leptonic pair. The effect of eikonalization of the universal "bare" dipole-target elastic amplitude in the saturation regime takes into account the principal part of the gap survival probability. We present predi

This paper presents a novel method for the analysis of heart rate variability (HRV) during exercise stress testing enhanced with respiratory information. The instantaneous frequency and power of the low frequency (LF) and high frequency (HF) bands of the HRV are estimated by parametric decomposition of the instantaneous autocorrelation function (ACF) as a sum of damped sinusoids. The instantaneous

This paper presents a noise cancelling 0.7– 3.8GHz receiver front-end implemented in 65nm technology. The circuit has a main path consisting of a high input impedance gm-stage, current-mode passive mixers and baseband amplifiers, where the input match is provided by frequency translational negative feedback from baseband to RF input. An auxiliary path with tunable gain is introduced to cancel nois

In this study, we demonstrate that articular cartilage chondrocytes are surrounded by the defining basement membrane proteins laminin, collagen type IV, nidogen and perlecan, and suggest that these form the functional equivalent of a basement membrane. We found by real-time PCR that mouse chondrocytes express these four cardinal components of basement membranes and demonstrated by immunohistochemi

Dietary fibre and whole grains are recommended to prevent the development of type 2 diabetes. Low glycaemic index foods that are rich in fibre are recommended to control blood glucose levels. Gastric emptying, together with other factors, regulate the postprandial blood glucose response. A delay in the gastric emptying rate (GER) leads to a lower postprandial blood glucose concentration. However,

Phosphorylation of estrogen receptor alpha at serine 305 (ER alpha S305-P) by protein kinase A (PKA) or p21-activated kinase 1 (PAK1) has experimentally been associated with tamoxifen sensitivity. Here, we investigated the clinical application of this knowledge to predict tamoxifen resistance in ER-positive breast cancer patients. Using immunohistochemistry, a score including PAK1 and co-expressio

Popular Abstract in Swedish Sambandet mellan exponering för miljögifter och mineraler i fosterlivet och risken att ha ADHD diagnos i barndomen ADHD (uppmärksamhetsstörning med hyperaktivitet) är en neuropsykiatrisk funktionsnedsättning som drabbar barn och kan fortsätta till vuxen ålder. Antalet barn som diagnosticerats med ADHD har ökat under senare år. Om detta beror på att man fått mer kunskapPerfluorinated compounds (PFCs), phthalates, manganese and selenium are ubiquitous in the environment and humans and influence fetal growth and development. Register and biobank based case-control studies were conducted to investigate the relationship between prenatal exposure to these chemicals and attention deficit hyperactivity disorder (ADHD) in childhood. The study base comprised children bo

In this study, we sought evidence for alpha-synuclein (ASYN) expression in oligodendrocytes, as a possible endogenous source of ASYN to explain its presence in glial inclusions found in multiple system atrophy (MSA) and Parkinson's disease (PD). We identified ASYN in oligodendrocyte lineage progenitors isolated from the rodent brain, in oligodendrocytes generated from embryonic stem cells, and in

Background and Purpose-Previous studies suggest that genetic variation plays a substantial role in occurrence and evolution of intracerebral hemorrhage (ICH). Genetic contribution to disease can be determined by calculating heritability using family-based data, but such an approach is impractical for ICH because of lack of large pedigree-based studies. However, a novel analytic tool based on genom

Popular Abstract in Swedish Många cancerceller har ovanligt höga nivåer av proteinet DEK och i vissa fall av leukemi har man hittat en genetisk förändring som leder till en variant kallad DEK-NUP214. Man tror därför att DEK kan vara en av faktorerna som bidrar till att vanliga celler omvandlas till cancerceller. En sådan roll har visats i experimentella modeller där man även sett att cancerceller The DEK gene is upregulated in a growing number of cancers and translocated to form the DEK-NUP214 fusion gene in a subset of acute myeloid leukemia. In this thesis, we studied the cellular and molecular functions of the DEK and DEK-NUP214 proteins. We found that the expression of DEK is increased by the leukemia-associated fusion protein NUP98-HOXA9, suggesting that DEK may be a downstream mediat

Osteoblastoma is a bone forming tumor with histological features highly similar to osteoid osteoma; the discrimination between the tumor types is based on size and growth pattern. The vast majority of osteoblastomas are benign but there is a group of so-called aggressive osteoblastomas that can be diagnostically challenging at the histopathological level. The genetic aberrations required for osteo

Current response and gain spectrum of a terahertz quantum cascade laser is analyzed at different temperatures by a nonequilibrium Green's functions approach. The simulations are compared to recent results of time domain spectroscopy. Being able to retrieve higher harmonics of the response function, nonlinear phenomena in quantum cascade lasers are studied theoretically. For different temperatures,

Popular Abstract in Swedish Enterohemorragisk Escherichia coli (EHEC) EHEC är mycket virulent för människor, det räcker med så få som 50-100 bakterier för att man ska bli infekterad och utveckla symtom. Varje år rapporteras ca 300-500 fall av EHEC smitta i Sverige. Den stam som oftast isoleras från patienter är E. coli O157:H7. Reservoarer för EHEC är idisslare och framförallt kor. Kor är nämligHemolytic uremic syndrome (HUS) is characterized by non-immune hemolytic anemia, thrombocytopenia and acute kidney failure. The most common form of HUS is associated with gastrointestinal Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) infection. EHEC are non-invasive strains with Shiga toxin as the unique virulence factor. The aim of this study was to describe host-pathogen intera

Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. Previous work showed that glucose activates the transcription factor Nuclear Factor of Activated T cells (NFAT) in arteries ex vivo. NF

To evaluate the effect of alcohol cessation on the risk of developing laryngeal and pharyngeal cancers, combining available evidence in the scientific literature in a meta-analysis.

OBJECTIVE: Patients with non-muscle-invasive bladder cancer are traditionally followed by repeat cystoscopy and urine cytology. A fluorescence in situ hybridisation technique called UroVysion((R)) (UV) is now available for clinical diagnosis of urothelial cancer cells. The aim of the present study was to compare UV analysis with routine follow-up methods. METHODS: We studied an unselected cohort o

One of the main ways in which in-between time-spaces are organised and materialised in the urban environment is through waiting places. In his article we point to the transformative potential of waiting places, their role as actors in an urban web, and discuss briefly their societal role in recent historical changes. Public waiting places are today increasingly becoming pre-programmed: connected t

FTIR study of the evolution of multivacancy-oxygen-related defects in the temperature range 100-350 degrees C in Czochralski-grown Si samples irradiated with different particles (10 MeV electrons and 5 MeV neutrons) has been carried out. Appearance of two absorption bands positioned at 833.4 and 842.4 cm(-1) has been found upon annealing of the divacancy related absorption band at 2767 cm(-1). The