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BACKGROUND: Anandamide, a proposed endogenous cannabinoid (CB) agonist, has been shown to enhance neurogenic responses in vitro of the rat corpus cavernosal tissue (CC). However, no information is available on the distribution of CB-receptors or effects by anandamide in CC from primates or humans. OBJECTIVE: To characterize the distribution of CB-receptor isoforms in the human and primate CC and t

To evaluate an intervention aimed at enriching day centres for people with psychiatric disabilities by exploring staff experiences from developing and implementing the intervention.

A design for generating distributed input data for a regionalized version of the steady-state model PROFILE was tested by Monte Carlo simulations of critical loads of acidity for 67 sites within a south Swedish municipality, Svalov. Input and output data were integrated in a geographic information system for data manipulation and to facilitate its use in local planning. Pooled standard deviations

Currently, no ideal prostate cancer (PCa) diagnostic or prognostic test is available due to the lack of biomarkers with high sensitivity and specificity. There is an unmet medical need to develop combinations of multiple biomarkers which may have higher accuracy in detection of PCa and stratification of aggressive and indolent cancer patients. The aim of this study was to test two biomarker gene p

Indoor air measurements were conducted in one unoccupied apartment of a ‘near-zero-energy’ residential building with a unique, wooden construction. Ozone, NO2, fine particles and volatile organic compounds, formaldehyde, acetaldehyde and peroxyacetyl nitrate (PAN) were measured under ‘as is’ conditions and after intentional intervention by adding ozone to simulate an ambient air ozone episode. Und

Swedish concrete dams are designed and assessed based on deterministic design using safety factors. The combination of increasing age, new methods for calculation of design floods and increasing demands by society to ensure a high level of safety, has resulted in upgrading and rebuilding needs for dams. When safety is re-evaluated it is important that evaluation is based on modern safety concepts.

Abstract Objective. The purpose of this pilot study was to evaluate the long-term clinical performance of implant-supported full-arch zirconia-based fixed dental prostheses (FDPs). Materials and methods. Ten patients received full-arch zirconia-based (Cercon) mandibular FDPs supported by four implants (Astra Tech). Nine patients received 10-unit FDPs and one patient received a 9-unit FDP. The FDPs

In the context of global R&D, we connect literature on knowledge management to a network-based theoretical framework helpful to analyse and explain the impact of globalisation of R&D on innovation performance. This framework is applied to two case companies, both global leaders within their respective industries, in order to analyse the extent to which their strategic globalisation of R&am

The scope for wastewater treatment plants (WWTPs) widens to consider not only water quality and cost, but also energy efficiency and greenhouse gas (GHG) emissions. The on-going research project, “Development and dynamic analysis of operational strategies for enhanced energy efficiency of wastewater treatment systems” aims to develop a tool for integrated evaluation of energy efficiency and greenh

The Churches of Bornholm in the Early Middle Ages: The architecture of the 15 12th-13th C churches of the island is seen as an expression of a feudal society dominated by king and archbishop. The towers are interpreted as local symbols of the feudal lordship, and the vaulted upper storeys as treasuries where the revenues - grain, pork, butter and herring - were stored. The article was first printe

Artikeln diskuterar den natursyn som tillskrivits "indianen" och visar hur den ingalunda är statisk utan tolkas och förhandlas fram i relation till det moderna samhällets kunskaper

To aid informed health sector decision-making, data from sufficient high quality economic evaluations must be available to policy makers. To date, no known study has analysed the quantity and quality of available Iranian economic evaluation studies. This study aimed to assess the quantity, quality and targeting of economic evaluation studies conducted in the Iranian context. The study systematical

Previous studies on lymphocytes have suggested that patients with head and neck squamous cell carcinoma (HNSCC) have an increased susceptibility for chromosomal damage induced by bleomycin, a known radiomimetic mutagen. However, it has so far not been possible to study whether this genetic instability is present also in the epithelial component of the upper aerodigestive tract mucosa, the tissue f

Patients with ulcerative colitis (UC) and Crohn´s colitis are at increased of developing colorectal cancer (CRC). However, recent studies suggest that the risk is now less than previously thought. Well established risk factors include extent and duration of disease, primary sclerosing cholangitis (PSC) and a family history of CRC. Recently inflammation (both microscopic and macroscopic) has been s