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Overdoses, suicidal behaviour and clinical characteristics in heavy drug users. Studies in the Criminal Justice System.

Background: Substance use disorders and complications, such as drug overdose (OD) and suicide attempt (SA), are common among criminal justice clients. Methods: Since 2001, the Swedish Prison and Probation Service has assessed substance-using clients with the Addiction Severity Index (ASI), a semi-structured instrument widely used to examine substance-related problems in different domains of life.

Onset of cellular instability in adiabatic H-2/O-2/N-2 premixed flames anchored to a flat-flame heat-flux burner

The onset of cellular instability in adiabatic H-2/O-2/N-2 premixed flames anchored to a heat-flux burner is investigated numerically. Both hydrodynamic instability and diffusional-thermal instability are shown to play an important role in the onset of cellular flames. The burner can effectively suppress cellular instability when the flames are close to the burner, otherwise the burner can suppres

"Sexual pleasure on equal terms": young women's ideal sexual situations

Objective: The aim of this study was to identify young women's ideal images of sexual situations and expectations on themselves in sexual situations. Study design: We conducted audio-taped qualitative individual interviews with 14 women aged 14 to 20 years, visiting two youth centers in Sweden. Data were analysed with constant comparative analysis, the basis of grounded theory methodology. Results

Protein Modifications by Low Molecular Weight Chemicals Inducing Airways Diseases

Airways diseases are one of the most common health effects in the western world today. It has been shown that low molecular weight chemicals (LMWC) can cause airways diseases. The mechanisms for these diseases are not well known in most cases. Also, methods for biological monitoring of exposure are not available for many of these LMWC. This limits the possibility for diagnostics and prevention. T

Experimental and modeling study of laminar burning velocity of biomass derived gases/air mixtures

Laminar burning velocities of four biomass derived gases have been measured at atmospheric pressure over a range of equivalence ratios and hydrogen contents, using the heat flux method on a perforated flat flame burner. The studied gas mixtures include an air-blown gasification gas from an industrial gasification plant, a model gasification gas studied in the literature, and an upgraded landfill g

Assessing the risk of N leaching from forest soils across a steep N deposition gradient in Sweden.

Nitrogen leaching from boreal and temporal forests, where normally most of the nitrogen is retained, has the potential to increase acidification of soil and water and eutrophication of the Baltic Sea. In parts of Sweden, where the nitrogen deposition has been intermediate to high during recent decades, there are indications that the soils are close to nitrogen saturation. In this study, four diffe

tmRNA-SmpB complex mimics native aminoacyl-tRNAs in the A site of stalled ribosomes

Bacterial ribosomes stalled on faulty, often truncated, mRNAs lacking stop codons are rescued by trans-translation. It relies on an RNA molecule (tmRNA) capable of replacing the faulty mRNA with its own open reading frame (ORF). Translation of tmRNA ORF results in the tagging of faulty protein for degradation and its release from the ribosome. We used single-particle cryo-electron microscopy to vi

Non-traditional stochastic models for ocean waves

We present two flexible stochastic models for 2D and 3D ocean waves with potential to reproduce severe and non-homogeneous sea conditions. The first family consists of generalized Lagrange models for the movements of individual water particles. These models can generate crest-trough and front-back statistically asymmetric waves, with the same degree of asymmetry as measured ocean waves. They are s

Understanding and supporting large-scale requirements management

Large market-driven software companies face new challenges in requirements engineering and management that emerged due to their recent extensive growth. At the same time, the pressure generated by competitors’ and users’ expectations demands being more competitive, creative and flexible to more quickly respond to a rapidly changing market situation. In the pursuit of staying competitive in this co

Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention

Background: The objective was to investigate in a group of obese subjects the course in skeletal muscle phospholipid (SMPL) fatty acids (FA) during a 24-weeks weight maintenance program, which was preceded by a successful very low calorie dietary intervention (VLCD). Special focus was addressed to SMPL omega-3 FA, which is a lipid entity that influences insulin action. Methods: Nine obese subjects

Simulating Spinal Border Cells and Cerebellar Granule Cells under Locomotion - A Case Study of Spinocerebellar Information Processing.

The spinocerebellar systems are essential for the brain in the performance of coordinated movements, but our knowledge about the spinocerebellar interactions is very limited. Recently, several crucial pieces of information have been acquired for the spinal border cell (SBC) component of the ventral spinocerebellar tract (VSCT), as well as the effects of SBC mossy fiber activation in granule cells

On the role of hydrophobic interactions in cellulose dissolution and regeneration: Colloidal aggregates and molecular solutions

The development of strategies for dissolution and regeneration of cellulose constitutes an increasingly active research field due to the direct relevance for many production processes and applications. A wide variety of suitable solvents for cellulose are already available. However, cellulose solvents are of highly different nature reflecting the great challenges in the understanding of the subtle

Measuring hybridization in GaInAs/InP electron billiard arrays

We study low temperature magnetoconductance fluctuations in arrays of electron billiards in an effort to quantitatively measure hybridization between array elements. In contrast to previous research in the 'open' regime, which is mostly limited to the canonical AlxGa1-xAs/GaAs heterostructure, our devices are etched into the Ga0.25In0.75As/InP heterostructure. To chart hybridization (i.e. the exte