Differences have been observed in the relationship between leptin and metabolic perturbations in glucose homeostasis. Because no information is available from indigenous African populations with diabetes, the purpose of this study was to investigate the possible associations between leptin and different clinical and biochemical characteristics of a large group of subjects with type 2 diabetes mell

Organophosphate hydrolase containing hexahistidine tag at the N-terminus of recombinant protein (His(6)-OPH) and expressed in Escherichia coli cells was purified using supermacroporous polyacrylamide-based monolith columns with immobilized metal affinity matrices [Me2+-iminodiacetic acid (IDA)-polyacrylamide cryogel (PAA) and Me2+-N,N,N'-tris (carboxymethyl) ethylendiamine (TED)-PAA]. Enzyme prepa

We classify all weak traveling wave solutions of the Degasperis-Procesi equation. In addition to smooth and peaked solutions, the equation is shown to admit more exotic traveling waves such as cuspons, stumpons, and composite waves.

The RGD sequence is present in many extracellular matrix proteins and intracellular proteins, including caspases. Synthetic RGD peptides may affect adhesion, migration and tumour metastasis, or directly induce apoptosis. Several RGD peptides were synthesised, and their anti-adhesive and cytotoxic properties were analysed in vitro. The most active peptide (poly RGD) was also tested in vivo to asses

To achieve software product quality professional skill and knowledge is important. The way to reach software product quality is often structured approaches for software quality such as SPI and CMM which have been criticized for lack of a knowledge perspective. The view taken in this study is that software product quality is related to interpretations and understanding in practice, and thus on prac

Infrared (IR) dryers are widely used in the paper industry for drying coated paper grades. However, there is limited knowledge regarding the efficiency of IR dryers. This study was undertaken to investigate the radiation efficiency and the total efficiency of electric IR dryers. Radiation efficiency was measured in the laboratory and on an industrial machine. The results indicate that radiation ef

Linkage analysis of F-2 crosses has led to identification of large numbers of quantitative trait loci (QTL) for complex diseases, but identification of the underlying genes has been more difficult. Reasons for this could be complications that arise from separation of interacting or neighboring loci. We made a partial advanced intercross (PAI) to characterize and fine-map linkage to collagen-induce

Restenosis is a major problem after balloon angioplasty and stent implantation. The aim of this study is to introduce gadolinium neutron capture brachytherapy (GdNCB) as a suitable modality for treatment of stenosis. The utility of GdNCB in intravascular brachytherapy (IVBT) of stent stenosis is investigated by using the GEANT4 and MCNP4B Monte Carlo radiation transport codes. To study capture rat

PURPOSE: Nitric oxide (NO) and carbon monoxide (CO) have been suggested to relax smooth muscle by activating soluble guanylate cyclase (sGC), binding to the same site of the enzyme. 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole (YC-1) (Cayman Co., Malmö, Sweden) increases the catalytic rate of sGC by binding to an allosteric site. We investigated whether YC-1 can modulate the relaxant responses o

In this study, we examined the onset and duration of local analgesic effects of bupivacaine incorporated into biodegradable microcapsules (extended-duration local anesthetic; EDLA) administered as subcutaneous infiltrations in different doses in humans. In 18 volunteers, the skin on the medial calf was infiltrated with 10 mL of EDLA, and the opposite calf was infiltrated with 10 mL of aqueous bupi

I examined the costs of producing and maintaining floral structures in Nigella degenii (Ranunculaceae). To test for such costs, I subjected plants of two populations to flower or perianth removal and then evaluated allocation to subsequently produced flowers, fruits, and seeds. Based on data from a flower removal experiment, the amount of resources allocated to flowers during the staminate and pis

We analyze the propagation of electromagnetic waves in nonlinear, bianisotropic, nondispersive, homogeneous media using simple waves and six-vector formalism. The Maxwell equations are formulated as an eigenvalue problem, whose solutions are equivalent to the characteristic propagation directions. We solve the oblique incidence of plane waves in vacuum on a half space of nonlinear material, and pr

An experimental design was used to determine optimal conditions for refolding of a recombinant thermostable and alkaline active xylanase from Bacillus halodurans in PEG-phosphate two-phase system. The influence of different experimental variables on the enzyme recovery has been evaluated. To build the mathematical model and minimize the number of experiments for the design parameters, response sur

Populärvetenskaplig artikel om missbruket av fribrevsrätter inom den svenska statsförvaltningen 1643-1719.

Evaluation of various methods in clinical practice is often based on interpretations by two or more observers. Such data need to be analysed with correct statistics, or the results and conclusions may be misleading. In this study, the use of measures of agreement for ordinal data in five international nursing journals is reviewed and various methods for measuring agreement are presented and discus