The concentrations of endogenous hormones differ between women with twin and singleton births, with a possible influence on the risk of cancer. We used the nationwide Swedish Family-Cancer Database, including 30,409 women with a twin birth, to examine the subsequent risks of breast, endometrial, and ovarian cancers. Relative risks (RRs) were calculated in a log-linear Poisson regression model of p

OBJECTIVES: To estimate sibling risk of hospitalization for children with sleep disordered breathing (SDB), diagnosed with (1) obstructive sleep apnea syndrome (OSAS), or (2) adenotonsillar hypertrophy in the total Swedish population.DESIGN, SETTING, AND PARTICIPANTS: Using the MigMed database at the Karolinska Institute, we divided the population of Sweden aged 0-18 years into sibling groups base

BACKGROUND: The aim of this study was to investigate possible associations between educational level, occupation, and hospitalization for inflammatory bowel disease.METHODS: A nationwide database was constructed by linking the Swedish Census to the Hospital Discharge Register in order to obtain data on all first hospitalizations for Crohn's disease (CD) and ulcerative colitis (UC) in Sweden during

OBJECTIVES: To quantify the sibling risk of RA, SLE and AS. To analyse the concordant and discordant associations between RA, SLE and AS.METHODS: Follow-up study of all individuals and their siblings born in or after 1932 and hospitalized for RA, SLE or AS between 1973 and 2004 (32 yrs). Data were retrieved from a comprehensive dataconstructed by using several national Swedish data registers, incl

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive disabling condition, for which tobacco smoking, environmental pollution, inherited alpha-antitrypsin deficiency and their interactions are predisposing factors. We carried out a family study on COPD in order to address the role of heritable and environmental risk factors at a population level.METHODS: In a nationwide study o

Arbuscular mycorrhizal fungi (AMF) are commonly present in wetlands, but their functional role there is not well understood. We have quantified the carbon (C) allocation from rice to AMF under different flooding regimes, using stable isotope labeling (13CO2), and assessed the potential phosphorus (P) delivery from AMF to rice by profiling the expression of plant and fungal P transporter genes. The

Dysregulation of autophagy has been observed in obesity and type 2 diabetes. Salt-inducible kinase 2 (SIK2), a member of the AMPK-related kinase family, is downregulated in adipocytes from obese or insulin resistant individuals and was previously demonstrated to regulate autophagy in cancer and normal cell lines. The aim of this study was thus to investigate a potential role of SIK2 in the regulat

Peninsular India is a collage of Archaean cratonic domains separated by Proterozoic mobile belts. A number of cratonic basins, known as “Purana basins” in the Indian literature, formed in different parts of the Indian Peninsula during extensional tectonic events, from Paleoproterozoic through Neoproterozoic times. In this contribution, we present a diversity of new geochronological data for differ

Aims Our aim was to examine the Elixhauser and Charlson comorbidity indices, based on administrative data available before surgery, and to establish their predictive value for mortality for patients who underwent hip arthroplasty in the management of a femoral neck fracture. Patients and Methods We analyzed data from 42 354 patients from the Swedish Hip Arthroplasty Register between 2005 and 2012.

Planar monopole antennas are popular due to their attractive properties, but their operating mechanisms are still not well understood. Based on image theory, planar monopoles can be analyzed using their dipole counterparts. Here, the bandwidth and radiation pattern of planar dipoles is studied in detail using characteristic mode analysis for different design parameters. The results show that insig

Urban growth is crucial for modernisation, and the wave of new towns in China since the 1980s is one example of a strategy employed by policymakers to encourage the process. This column analyses the long-run success of a town foundation policy in Sweden between 1570 and 1810. While the ‘artificially’ created towns failed to grow in the short term, they eventually began to grow and thrive, and toda

RATIONALE: Obstructive sleep apnea (OSA) and depression are common among adults with coronary artery disease (CAD). OBJECTIVES: To determine the impact of continuous positive airway pressure (CPAP) treatment on depression in adults with CAD and nonsleepy OSA. METHODS: This was a secondary analysis of the RICCADSA (Randomized Intervention with CPAP in CAD and Sleep Apnea) trial, conducted in Sweden

Den senaste reformen av EU:s gemensamma jordbrukspolitik (CAP) sjösattes 2015 med avsikten att göra det europeiska jordbruket mer konkurrenskraftigt och mer hållbart. Syftet med den här rapporten är att analysera vilka effekter reformen kan väntas få på svenskt jordbruk på områdena konkurrenskraft och miljö, för att undersöka om målen med reformen uppfylls eller ej. Analysen bygger på simuleringar

A controlled experiment was carried out by doing geophysical measurements on a purpose-built heap consisting of two different industrial waste fractions, called NF ( non-ferrous metal) and SLF (shredder light fraction), from the recycling plant of Stena Metall in Halmstad, Sweden. The purpose of the experiment was to see if it was possible to distinguish the different types of material using geoph

Survival from soft tissue tumors (STTs) has been improved because of the successful treatment. One of the late sequelae in STT survivors is the development of a second malignancy. The present study aimed at quantifying risks for second malignancies in patients with STTs, and risks for second STTs after other primary malignancies. Adjusted standardized incidence ratios (SIRs), calculated from the S

The effects of socio-economic/occupational factors on gastric cancer at various subsites (including corpus, cardia and unspecified cancers) are not well known. To investigate this issue, we carried out a follow-up study on the economically active Swedish population, based on the Swedish Family-Cancer Database. We calculated standardized incidence ratios and 95% confidence intervals for different o

The reasons for the high risk of contralateral breast cancer are not understood, although polygenic mechanisms have been suggested to be involved. The nationwide Swedish Family-Cancer Database was used to examine the interaction of the risks for contralateral and familial cancer. Relative risks were separately determined for contralateral and familial breast cancers, and these were tested for addi