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The Jerusalem Question in a Regional Context
Trumps motstånd mot kärnkraftsavtalet kan öka motsättningarna i Iran
More data needed to establish maternal breast milk IgG as cause for anti-D hemolytic disease of fetus and newborn
Thymoma : a clinicopathological correlation of 1470 cases
We present 1470 surgical resections for thymoma identified in the pathology files of 14 institutions from 11 countries with the purpose of determining and correlating a simplified histological classification of thymoma and pathological staging with clinical outcome. The study population was composed of 720 men and 750 women between the ages of 12 and 86 years (average, 54.8 years). Clinically, 137
Smoking is the most significant modifiable lung cancer risk factor in systemic lupus erythematosus
Objective. To assess lung cancer risk in systemic lupus erythematosus (SLE), relative to demographics, drug exposures, smoking, and disease activity. Methods.We analyzed data from 14 SLE cohorts. We calculated adjusted HR estimates for lung cancer in SLE, relative to demographics, smoking, time-dependent medication exposures, and cumulative disease activity [mean adjusted SLE Disease Activity Inde
Jitter-Robust LQG Control and Real-Time Scheduling Co-Design
In real-time control systems, varying task response times may lead to delays and jitter in the delays in the feedback control loops, which adversely affects both performance and robustness. Standard LQG control design does not give any guarantees on robustness, while robust control design methods often do not handle controller timing uncertainty. We propose a sampled-data controller synthesis meth
Outcome and survival of myeloma patients diagnosed 2008-2015. Real-world data on 4904 patients from the Swedish Myeloma Registry
Epidemiology and outcome of myeloma are mainly reported from large university centers and collaborative groups, and do not represent ‘real-world’ patients. The Swedish Myeloma Registry is a prospective population-based registry documenting characteristics, treatment and outcome in newly diagnosed myeloma, including asymptomatic and localized forms, with the purpose of improving disease management
CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting
Tyrosine kinase inhibitors (TKIs) are highly effective for the treatment of chronic myeloid leukemia (CML), but very few patients are cured. The major drawbacks regarding TKIs are their low efficacy in eradicating the leukemic stem cells responsible for disease maintenance and relapse upon drug cessation. Herein, we performed ribonucleic acid sequencing of flow-sorted primitive (CD34+CD38low) and
Adaptive interface for mapping body movements to sounds
Contemporary digital musical instruments allow an abundance of means to generate sound. Although superior to traditional instruments in terms of producing a unique audio-visual act, there is still an unmet need for digital instruments that allow performers to generate sounds through movements in an intuitive manner. One of the key factors for an authentic digital music act is a low latency between
Ruling out risks in medical research
In medical research, it is not unusual that risks are ruled out without any specification the exact risk that was ruled out. This makes it difficult to balance expected health benefits and risk of harm when choosing between alternative treatment options. International guidelines for reporting medical research results are sufficiently specific when it comes to establishing health benefits. However,
Thermal performance of angled, V-shaped and leaning-V-shaped ribs in a rotating rectangular channel with 45° orientation
Purpose: The fluid flow in a rotating channel is obviously different from that in a stationary channel due to the existence of Coriolis force, which, in turn, enhances the heat transfer on the trailing side and reduces the heat transfer on the leading side. The purpose of this paper is to study various rib configurations combined with channel orientation on heat transfer and frictional loss in a r
Miller's principle, the principal principle, and other principles
Levels of aspiration and risk
Utilizing Coarse-Grained Modeling and Monte Carlo Simulations to Evaluate the Conformational Ensemble of Intrinsically Disordered Proteins and Regions
In this study, we have used the coarse-grained model developed for the intrinsically disordered saliva protein (IDP) Histatin 5, on an experimental selection of monomeric IDPs, and we show that the model is generally applicable when electrostatic interactions dominate the intra-molecular interactions. Experimental and theoretically calculated small-angle X-ray scattering data are presented in the
Effects of agglomerate model parameters on transport characterization and performance of PEM fuel cells
A three-dimensional, non-isothermal and two-phase flow model for proton exchange membrane (PEM) fuel cells is developed. In the cathode catalyst layer, a spherical agglomerate model with consideration of catalyst layer structure and liquid water effect is applied to determine the electrochemical kinetics. The size and structure of the agglomerates are determined by the following parameters, i.e.,
Ecological analysis of nutrient dynamics and phytoplankton assemblage in River Ganga system, Uttarakhand
Assessment of water quality in Upper Ganga Canal by using Comprehensive Pollution Index
Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7
Familial myelodysplastic syndromes arise from haploinsufficiency of genes involved in hematopoiesis and are primarily associated with early-onset disease. Here we describe a familial syndrome in seven patients from four unrelated pedigrees presenting with myelodysplastic syndrome and loss of chromosome 7/7q. Their median age at diagnosis was 2.1 years (range, 1-42). All patients presented with thr