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Direct electron transfer reactions of laccases from different origins on carbon electrodes

Electrochemical studies of laccases from basidiomycetes, i.e., Trametes hirsuta, Trametes ochracea, Coriolopsis fulvocinerea, Cerrena maxima, and Cerrena unicolor, have been performed. Direct (mediatorless) electrochemistry of laccases on graphite electrodes has been investigated with cyclic voltammetry, square wave voltammetry as well as potentiometry. For all mentioned high potential laccases di

The Greenland Ice Core Chronology 2005, 15-42 ka. Part 2: comparison to other records

A new Greenland Ice Core Chronology (GICC05) based on multi-parameter counting of annual layers has been obtained for the last 42 ka. Here we compare the glacial part of the new time scale, which is based entirely on records from the NorthGRIP ice core, to existing time scales and reference horizons covering the same period. These include the GRIP and NorthGRIP modelled time scales, the Meese-Sowe

Relay Feedback Auto-tuning of Process Controllers – A Tutorial Review

The PID relay auto-tuner of Astrom–Hagglund is one of the simplest and most robust auto-tuning techniques for process controllers and has been successfully applied to industry for more than 15 years. This tuner is based on an approximate estimation of the critical point on the process frequency response from relay oscillations. Many developments have recently been reported to extend its applicatio

Estimation of local near-surface wind conditions - a comparison of WASP and regression based techniques

This study compares the performance of different models used to assess the local wind near-surface conditions at an agricultural site in Scania, southern Sweden. The methods are: (a) the WASP model (Wind Analysis and Application Program), (b) separate linear regressions of the two wind vector components, (c) a regression model based on vector correlation, and (d) linear regression of scalar wind.

Chromosome aberrations in prophylactic mastectomies from women belonging to breast cancer families

Short-term cultures of samples from eight prophylactic mastectomies from five unrelated women who were genetically predisposed to breast cancer were analyzed cytogenetically. Clonal chromosome abnormalities were detected in five breasts. Three samples from two women had aberrations involving the short arm of chromosome 3, with a breakpoint in 3p14 in common. Three samples from three women had rear

Disease-related variations of the glycosylation of haptoglobin in the dog

Haptoglobin phenotypes have been shown in human medicine to be related to the prevalence of various diseases. Furthermore, abnormal glycosylation of haptoglobin has been reported as a consequence of liver disease, cancer and immunological disorders in man. To our knowledge, similar findings have not, so far, been reported in canine disease. The present paper describes a method for investigation of

Structural basis for pleckstrin homology domain mutations in X-linked agammaglobulinemia

Deficiencies in a tyrosine kinase, designated Btk, cause X-linked agammaglobulinemia (XLA) in man, a hereditary defect of B-cell differentiation. Mutations in the newly found PH domain located at the N-terminus of Btk have been shown to be the direct cause of XLA, and here two new mutations, T33P and V64F, are presented. Btk is thus far the only protein in which mutations of the PH domain have bee

Interactions of novel, nonhemolytic surfactants with phospholipid vesicles

PEG-12-acyloxystearates constitute a novel class of pharmaceutical solubilizers and are synthesized from polyethylene glycol and 12-hydroxystearic acid, which has been esterified with a second acyl chain. The hemolytic activity of these surfactants decreases drastically with increasing pendant acyloxy chain length, and surfactants with an acyloxy chain of 14 carbon atoms or more are essentially no

Early trauma responses and psychopathology. Setting up the stage.

Research on short- and long-term response to trauma has been expanding over the past twenty years and has found new urgency in recent national and international events. As our understanding of risk factors for who will be most severely affected by trauma expands, what we don't know about the interactions between vulnerabilities and risk factors, peritraumatic and posttraumatic factors, physiologic

Constraint-driven identification of application specific instructions in the DURASE system

This paper presents a new constraint-driven method for fast identification of computational patterns that is a part of DURASE system (Generic Environment for Design and Utilization of Reconfigurable Application-Specific Processors Extensions). The patterns identified by our system form a base for application specific instruction selection and processor extension generation. Our method identifies a

Subcellular distribution of spermidine/spermine N(1)-acetyltransferase

The subcellular distribution of the polyamine catabolic enzyme spermidine/spermine N(1)-acetyltransferase (SSAT) was studied in L56Br-C1 cells treated with 10muM N(1),N(11)-diethylnorspermine (DENSPM) for 24h. Cells were fractioned into three subcellular fractions. A particulate fraction containing the mitochondria was denoted as the mitochondrial fraction. After DENSPM treatment, an increase in S

MiniReview: Bioinformatic study of bile responses in Campylobacterales

Campylobacter, Helicobacter and Wolinella are genera of the order Campylobacterales, belonging to the class Epsilonproteobacteria. Their habitats are various niches in the gastrointestinal tract of higher animals, where they may come into contact with bile. Microorganisms in these environments require mechanisms of resistance to the surface-active amphipathic molecules with potent antimicrobial ac

Temporal correlation scheme for spectroscopic gas analysis using multimode diode lasers

The reliability of diode lasers used in spectroscopic applications is limited by their intrinsic multimode and mode-jump behavior when wavelength-tuned by current or temperature. We report on a scheme for gas analysis based on temporal correlation between absorption signals from an unknown external and a known reference gas concentration, simultaneously recorded when the diode laser wavelength is

Arthrodesis of the ankle secondary to replacement

One hundred total ankle arthroplasties were performed in our department between 1974 and 1994, and of these, 21 have been reoperated on with arthrodesis due to septic or nonseptic failures after 6 months to 15 years (median 40 months). Immobilization using a Hoffman external fixator was the dominating method. The total ankles were of six different designs. Sixteen of the 21 patients suffered from

One-year endometrial safety evaluation of a continuous combined transdermal matrix patch delivering low-dose estradiol-norethisterone acetate in postmenopausal women.

Objective: To evaluate the safety and endometrial protection of low-dose transdermal estradiol (E2)/norethisterone acetate (NETA) patches (Estalis 25/125) in terms of post-treatment incidence of endornetrial hyperplasia/cancer after 1 year of treatment in postmenopausal women with intact uteri. Methods: Patients were randomized to receive either transdermal E2/NETA (delivering daily doses of E2 25