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Tailoring Broadband Large Chiral Response in All-Dielectric Twisted L-shape Metamaterial Platforms

This study presents the fabrication of all-dielectric silicon-based twisted L-shape metamaterials using a two-step electron-beam glancing angle deposition approach. Systematic chiroptical characterization and optimization are performed through Mueller matrix generalized spectroscopic ellipsometry and finite element modeling, demonstrating tunable, broadband chirality response with potential applic

Demystifying the localized relationships between population health outcomes and multi-source determinants: A spatially varying GeoAI framework

Data-driven modeling frameworks have become essential tools for guiding surveillance strategies and informing public health policies across diverse population health challenges. Accurate, fine-scale disease estimates often lacking from direct surveys are critical for policy planning, given that spatial heterogeneity and nonlinear dynamics among determinants of health challenge classical models, li

How teachers build trust with students in the presence of GenAI

Trust is a prerequisite for successful learning.From previous work we know that teachers use multiplestrategies to build trust with students – for example todemonstrate knowledge, skill and competence, or showinginterpersonal care and concern. We also know from studentsthat they trust teachers who ask, listen, and respond. But sincewe conducted those studies, Generative Artificial Intelligence(Gen

QUANTIFYING UNCERTAINTY IN INSAR-DERIVED DISPLACEMENT MEASUREMENTS FOR BRIDGE MONITORING

Bridge monitoring is essential for ensuring their long-term safety, reducing disruptions, and supporting economic and social activities. Traditional monitoring techniques rely on periodic inspections and contact-based sensing systems, which, while effective, have limitations due especially to high installation and maintenance costs. Satellite-based Synthetic Aperture Radar Interferometry (InSAR) o

Differentiation of Human Induced Pluripotent Stem Cells Toward Implantable Chondroprogenitor Cells

Background. Post-traumatic chondral and osteochondral lesions can be treated with autologous chondrocyte implantation (ACI), but the high cost of autologous cell expansion under strict Good Manufacturing Practice (GMP) regulations limits patient access. Stem cell–based advanced therapy medicinal products (ATMPs) offer more cost-effective alternatives, with human induced pluripotent stem cells (iPS

Economic and Environmental Optimization of Retrofitting Options for a Community Building : A Case Study from Förslöv-Grevie Parish, Sweden

The research evaluated retrofitting options for a threestory church community building in Grevie, Sweden, assessing the impacts on energy efficiency, life cycle cost, and environmental concerns. An energy model was generated in IDA ICE to simulate the building performance. Various improvements were tested in two separate retrofit package scenarios. They had the following measures in common: the ad

CHILDREN’S TRAVEL AND SUSTAINABILITY

Transport has a large impact on children’s lives from facilitating or limiting their mobility and access to destinations to impacting their health and wellbeing. However, cities have primarily focused on facilitating motor vehicle travel, which is an adult-exclusive mode. Likely, as a result, many children are escorted to places. In this chapter, we summarize literature on children’s travel from a

Human Brain Cell-Type-Specific Aging Clocks Based on Single-Nuclei Transcriptomics

Aging is the primary risk factor for most neurodegenerative diseases, yet the cell-type-specific progression of brain aging remains poorly understood. Here, human cell-type-specific transcriptomic aging clocks are developed using high-quality single-nucleus RNA sequencing data from post mortem human prefrontal cortex tissue of 31 donors aged 18–94 years, encompassing 73,941 high-quality nuclei. Di

Advanced Emissivity Tuning Via Femtosecond Laser Surface Engineering

Tuning the spectral and directional characteristics of thermal emission is critical for advancing technologies such as thermophotovoltaics (TPVs), passive thermal radiative cooling (PTRC), and solar thermophotovoltaics (STPVs), yet scalable fabrication methods remain limited. Here, femtosecond laser surface processing (FLSP), a top-down ablation and re-solidification approach is employed, to creat

Influenza A Infection Increases Severity of Acute Ischemic Stroke Through Neutrophil Activation and Hypercoagulability

BACKGROUND: Respiratory viruses, such as influenza viruses and SARS-CoV-2, cause severe infections of the respiratory system. Cohort studies and clinical observations indicate that patients with severe influenza A virus (IAV) infections are at an increased risk of developing an ischemic stroke event. However, the underlying mechanisms remain elusive. To this end, we investigated the consequences o

ESR Essentials : post-treatment breast cancer surveillance from mammography to a more personalised approach-practice recommendations by the European Society of Breast Imaging

Abstract: The breast cancer long-term survival rate has improved; early detection of local recurrence and second primary cancers has been crucial to this success. Mammography is the standard imaging technique for follow-up, but its sensitivity is affected by breast density and post-treatment changes. This article discusses the role of mammography in the follow-up of women after breast cancer treat

Unraveling the conformational landscape of amyloid precursor protein intracellular domain

The amyloid precursor protein intracellular domain (AICD), a cleavage product of amyloid precursor protein implicated in Alzheimer disease and amyloid lateral sclerosis, is a functionally important but structurally elusive intrinsically disordered protein. In this study, we investigate the conformational ensemble of a 35-residue AICD segment encompassing the conserved YENPTY motif using molecular

Navigating Inequality in Science : Structure and Agency in International Research Collaboration

International research collaboration stands at a pivotal juncture, shaped by enduring structural inequalities between high-, middle-, and low-income countries and challenged by a trend of withdrawal from international collaboration. These asymmetries can create a misalignment between global scientific progress and the capacity to address pressing societal crises, which often disproportionately aff

Filtenna-Oriented Mode Control and Resonance Fusion in Square SIW Cavities for 5G Millimeter-Wave Applications

This paper presents a single-layer filtering antenna (filtenna) based on a compact square substrate-integrated waveguide (SIW) cavity for millimeter-wave (mmWave) applications. The cavity operates in the fundamental TE110 mode to enable beam scanning, while a central shorting via introduces the TE210 mode, broadening the bandwidth. A radiating slot, placed at high-intensity regions of both modes,

Navigating uncertainty: Trauma quality improvement in urban India

Background and aimImproving the quality of health care is a global priority, yet many conventional quality improvement approaches, rooted in industrial models of standardisation and control, struggle to account for the uncertainty and complexity of clinical care. Trauma, defined as external injury and the body's physiological response, causes about 4.4 million deaths each year. The impact is great

Speaker’s comfort and vocal effort in different room acoustic conditions : A controlled field experiment in a university lecture room

Speaking in poor acoustic conditions constitutes a risk factor for voice disorders. This study investigated how speaker’s comfort and vocal effort were affected during short speech tasks in four different room acoustic configurations. Voice recordings of the speech tasks and self-evaluations of the speaker’s comfort were collected from 15 participants in four room acoustic configurations as part o

Treatment and follow-up of vascular graft and endograft infection : Delphi consensus document

Scope: Vascular graft or endograft infection (VGEI) is a severe complication requiring a multidisciplinary approach combining surgery and antimicrobial therapy. This study aimed to develop expert consensus on the management and follow-up of VGEI, with a focus on antimicrobial strategies. Methods: A modified Delphi method was conducted to reach consensus on key aspects of VGEI care, including antim

Local Strain Tuning in Cu Nanoparticles through Glucose-Mediated Synthesis

Cu nanoparticles are widely used in different fields. Controlling the Cu oxidation state and the local strain is fundamental for optimizing its efficiency in processes, such as catalytic reactions. In this work, Cu nanoparticles were synthesized by using glucose as a reducing agent. Different synthesis conditions led to nanoparticles with a tunable local strain and Cu(0)/Cu 2O ratio. The amounts o

Goniometric Investigation of Spectral Scattering from Insect Wings in Near Infrared

Insect wing interference is highly sensitive to the membrane thickness and has shown remarkable potential to differentiate insect species, both ex vivo in laboratory settings and for free-flying insects in situ. While several studies have reported diversity of wing interference patterns, no study has linked this resonant coherent scattering from membranes to the goniometric scattering phase functi