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The Nordic countries have a long tradition of large-scale biobanking and comprehensive, population-based health data registries linkable on unique personal identifiers, enabling follow-up studies spanning many decades. Joint Nordic biobank-based studies provide unique opportunities for longitudinal molecular epidemiological research. The purpose of the present paper is to describe the possibilitie

The effects of varying extracellular concentrations of K+ and Ca2+ [K+]o and [Ca2+]o on force development and membrane potential were investigated in the guinea-pig mesotubarium. At [K+]o up to 40 mM, spontaneous action potentials were present, while higher [K+]o gave sustained contractures at a stable membrane potential (-24 to -12 mV for [K+]o from 60 to 120 mM). Tension decreased successively w

Since akinete germination is triggered by light and the action spectrum for this process has features in common with the spectra of the two photochromic pigments, phycochromes b and d, a search was made for the presence of these phycochromes in akinetes of the blue-green alga. Anabaena variabilis Kützing. Allophycocyanin-B was also looked for, since the action spectrum for akinete germination poin

Parabolic planar compound refractive lenses (CRLs) made from glassy carbon by means of laser ablation are presented. They have radii of curvatures of 5 and 200 mu m and geometric apertures of 40 and 900 mu m, respectively. The numbers of biconcave elements in the CRLs were 4, 7, and 200. The planar lenses allow formation of a linear focus of length comparable with the depths of their profiles. Usa

In sheep's fescue, Festuca ovina, genes coding for the cytosolic enzyme phosphoglucose isomerase, PGIC, are not only found at the standard locus, PgiC1, but also at a segregating second locus, PgiC2. We have used PCR-based sequencing to characterize the molecular structure and evolution of five PgiC1 and three PgiC2 alleles in F. ovina. The three PgiC2 alleles were complex in that they carried two

The influence of pH on membranes of different materials and different cut off has been studied. One ceramic microfiltration membrane and three synthetic ultrafiltration membranes were included in the study. The pH of an acidic (C-stage) and and alkaline (E-stage) bleaching effluent was varied. For the E-stage effluent the membrane performance seemed to be correlated to the cut off of the membrane.

BACKGROUND: Selecting patients with a low risk of hypocalcemia is mandatory if patients are to be discharged on the first day after bilateral thyroidectomy. This study investigated the predictive value of intraoperative parathyroid hormone (PTH). METHODS: Thirty-eight patients underwent total or near-total thyroidectomy. Patients with or without biochemical and symptomatic hypocalcemia were compar

Popular Abstract in Swedish Basic Fibroblast Growth Factor (bFGF) är en av flera tillväxtfaktorer som finns lagrad i benvävnaden. bFGF framkallar celldelning och tillväxt hos många olika celltyper, däribland benceller (osteoblaster) och broskceller. bFGF kan stimulera till nybildning av blodkärl och även benvävnad. I denna avhandling undersökes om utifrån tillfört bFGF kan öka benbildning och vävnBasic Fibroblast Growth Factor (bFGF) is one of the endogenous factors found in bone matrix. bFGF is a mitogen for many cell types, including osteoblasts and chondrocytes. It can stimulate angiogenesis and osteoblast gene expression. The purpose of this study was to investigate whether exogenous bFGF can stimulate the formation of bone in bone grafts and in a bone graft substitute. All experiments

Calreticulin (CRT) is a eukaryotic, highly conserved, Ca2+-binding protein predominantly located in the endoplasmic reticulum (ER) lumen. In addition to being involved in the regulation of cellular Ca2+, calreticulin is a key quality control element during protein folding in the ER lumen. Tobacco (Nicotiana tabacum L.) suspension cells overexpressing a maize CRT (CRT1a) were used here to examine t

Popular Abstract in Swedish Syftet med denna avhandling är att undersöka mötet mellan den kyrkliga överheten och de olika lokalsamhällena sådant som det tog sig uttryck vid de kyrkliga visitationerna. I fokus står biskopsvisitationerna men även de visitationer som prostarna genomförde tas upp till behandling. Undersökningsområdet är Växjö stift och den tidsmässiga avgränsningen är 1650-1760. De frThe aim of this thesis is to investigate the encounter of the ecclesiastical authorities with the local community, as reflected in the church visitations. The focus is on the bishops' visitations, but there is also a brief examination of the deans' visitations, which are used for a comparison of the two types of inspections. The geographical limit of the study is the diocese of Växjö in southern S

I samband med att Kvinnofridsreformen i Sverige 1998 uppdrog regeringen åt brottsoffermyndigheten att undersöka mörkertalet i fråga om mäns våld mot kvinnor som ett komplement till den officiella statistik som brottsförebyggande rådet normalt svarade för. Ansvaret för studien tilldelades Eva Lundgren, professor i sociologi och Gun Heimer, överläkare och chef för RiksKvinnoCentrum. Tillsammans med

Objectives. To estimate the point prevalence (p.p.) of Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), polyarteritis nodosa (PAN) and Churg-Strauss syndrome (CSS) within a defined population in southern Sweden. Method. A cross-sectional p.p. study using multiple sources for case identification. The study area, a healthcare district around the city of Lund in southern Sweden (Mellers

Background: Work capacity correlates weakly to disease concepts, which in turn are insufficient to explain sick leave behavior. With data mainly from Sweden, a welfare state with high sickness absence rates, our aim was to develop an explanatory theory of how to understand and deal with work absence and sick leave. Methods: We used classic grounded theory for analyzing data from >130 interviews wi

NA44 uses a 512 channel Si pad array covering 1.5 < eta < 3.3 to study charged hadron production in 158 A GeV Pb+Pb collisions at the CERN SPS. We apply a multiresolution analysis, based on a Discrete Wavelet Transformation, to probe the texture of particle distributions event-by-event, by simultaneous localization of features in space and scale. Scanning a broad range of multiplicities, we look f

Binding of immobilized collagen-I (Cn-I) and fibronectin (Fn) by Lactobacillus acidophilus CRL 639 depends on cell-surface proteins. Capsule formation during the stationary growth phase has a negative effect on adherence of Cn-I and Fn. However, cells from the exponential growth phase. which produce no capsule, exhibit maximal binding. Binding is sensitive to trypsin, proteinase K, pronase E, and

GaAs(100) layers grown by low-temperature (LT) molecular beam epitaxy were studied by means of valence-band and core-level photoelectron spectroscopy. Small differences were found between valence-band spectra from the LT layers and corresponding layers grown at high temperature. In the Ga 3d spectra a new component was found in the LT-GaAs. The relative intensity of this component was found to be

Few cases of atrial fibrillation can be completely excused from the possibility of having some impact of potential importance in the aviation environment. The clinical pattern in paroxysmal disturbance is very wide and possible incapacitating phenomena are mainly haemodynamic. In contrast, chronic atrial fibrillation is mostly well-tolerated with only minimal haemodynamic effect, but there is a ri

Denna rapport syftar till att anvisa metoder för att beräkna eller bedöma risken för fuktskador, särskilt i träkonstruktioner. I rapporten ingår en allmän orientering i riskanalys, statistiska beräkningar enligt Monte Carlo-metoden samt andra beräkningar av riskfaktorer gällande fukt- och mögelangrepp.

Background: Maintenance treatment with inhaled corticosteroids is often required for asthmatic nursing women. Data on the transfer of inhaled corticosteroids from plasma to breast milk and the subsequent exposure of the breast-feeding infant has been unavailable. Objective: We sought to assess budesonide concentrations in milk and plasma of asthmatic nursing women receiving maintenance treatment w