Spasticity is a locomotory disability that is common after injury to the spinal cord. Monoamines such as serotonin and dopamine controls the activation of motoneurons, which in turn affects muscle. Aromatic L-amino acid decarboxylase (AADC) catalyzes formation of serotonin from 5-hydroxytryptophan and dopamine from L-dihydroxyphenylalanine. To study if there are cells in the primate spinal cord th

The effect of the buffer formulation in terms of buffer identity and ionic strength on the interaction between chicken egg lysozyme and carboxyl-modified polystyrene nanoparticles has been systematically studied. The time evolution of the fluorescence of a reporter molecule shows that lysozyme interacts with the nanoparticles in all the studied conditions. The interaction results in changes in pro

Spatially and temporally resolved measurements are of great importance in turbulent premixed flame studies, especially when investigating rapid processes such as when flame local extinction, re-ignition, or flashback occur in a reacting flow. Here, an experimental approach for simultaneously probing two different species at high frame rates (50 kHz) is presented by employing a multi-YAG laser syst

OBJECTIVES: Plant-derived natural substances, such as capsaicin, with potent antiproliferative activity against cancer cells in vitro are considered to be promising nutraceuticals in anticancer therapy. Nevertheless, the limited systemic bioavailability of phytochemicals may raise questions regarding the physiological relevance of their phytochemical effects in vivo. Thus, the search for novel phy

Deficient production of anti-viral interferons (IFNs) may be involved in causing viral-induced asthma exacerbations. Hence, drugs inducing lung IFN production would be warranted. Azithromycin may reduce asthma exacerbations but its modus operandi is unknown. Here, we investigated if azithromycin induces IFNβ expression in vitro in rhinovirus-infected bronchial epithelial cells from asthmatic donor

This article gives a glimpse of the early development of Automatic Control in Sweden covering the period up to the mid 1960s. Much of the early developments took place in industry and the defence establishments. Process control, particularly in the pulp and paper industry, power systems, and military projects were strong drivers for the technology. The article ends with the emergence of control in

This study has focused on: (i) differences in how males and females use the genes in the genome, (ii) how sex chromosomes evolve and (iii) how the evolutionary rate of genes are affected by the chromosome on which they are located on and the gene expression level they experience. A large-scale microarray was developed for the zebra finch, Taeniopygia guttata and techniques were developed so that t

In this paper an approach for employing risk and vulnerability analyses as the basis for emergency preparedness planning is discussed and exemplified using a case study. The study consisted of three connected parts: a broad scope hazard identification and analysis, an assessment of potential assistance needs should any of the hazards materialise and finally a mapping of actors and dependencies. Th

In this paper, signal waveform designs for TOA estimation with non-coherent receivers based on ultrawideband impulse radio are discussed. Four different transmit signal waveforms are analyzed, both with respect to their design constraints, and their precision ranging performance in IEEE 802.15.4a multipath channels. We introduce novel searchback and thresholding algorithms, and show that the rangi

Moving forward, higher education will face a variety of challenges, especially in 2020/2030, due to technological development and digitalization. Digitalization in society has grown, and society fosters digital citizenship to a greater extent. Students entering higher education today have grown up with the Internet and mobile devices. Daily life, schools, and work have also become more mobile beca