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Background: We aim to estimate population-attributable fractions (PAF) for 13 comorbidities potentially predisposing to hepatobiliary cancer of hepatocellular carcinoma (HCC), gallbladder cancer (GBC), cancers of the intrahepatic and extrahepatic bile ducts (ICC and ECC), and ampullary cancer. Methods: Patients were identified from the Swedish Inpatient Register from 1987 to 2018 and cancers from

Charge regulation is fundamental in most chemical, geochemical, and biochemical systems. Various mineral surfaces and proteins are well-known to change their charge state as a function of the activity of the hydronium ions, that is, the pH. Besides being modulated by the pH, the charge state is sensitive to salt concentration and composition due to screening and ion correlations. Given the importa

We show that in contrast to the conventional view of a mean-field Landau-type behavior, the oxygen octahedral tilt (R) and polarization (P) in the A3B2O7 Ruddlesden-Popper hybrid improper ferroelectric (Ca,Sr)3Ti2O7 exhibits the scaling behavior of a 2D Ising class near the para-to-ferroelectric transition temperature (Tc). We also show that P exhibits an additional transition from a 2D Ising to a

Retinitis pigmentosa (RP) is a frequent cause of blindness among the working population in industrial countries due to the inheritable death of photoreceptors. Though gene therapy was recently approved for mutations in the RPE65 gene, there is in general no effective treatment presently. Previously, abnormally high levels of cGMP and overactivation of its dependent protein kinase (PKG) have been s

In the concluding chapter, the editors take stock of the state of integration seventy years after the EU’s inception. In the early 2020s, the EU faces once again the fateful question of whether integration should proceed in a federal direction, or whether varied flexible solutions to concrete problems should guide its development instead. The stock-taking is seen against the acute challenges that

Hierarchical biomaterials have their place in the context of developing novel material systems particularly in the framework of sustainability. The key to their development is in controlling their assembly into hierarchical orders at various lengthscales. Thus, flow can be an asset in e.g. controlling orientation, however, resolving the hierarchical orientation dynamics of such systems remains a c

We study the notion of anonymous credentials with Publicly Auditable Privacy Revocation (PAPR). PAPR credentials simultaneously provide conditional user privacy and auditable privacy revocation. The first property implies that users keep their identity private when authenticating unless and until an appointed authority requests to revoke this privacy, retroactively. The second property enforces th

Photo-induced cross-linking of unmodified proteins (PICUP) has been used in the past to study size distributions of protein assemblies. PICUP may, for example, overcome the significant experimental challenges related to the transient nature, heterogeneity, and low concentration of amyloid protein oligomers relative to monomeric and fibrillar species. In the current study, a reaction chamber was de

Photography was born at the beginning of the 19th century as a tool for representing the world around us. With its advent, the scientific community found an ally to push back the frontiers of knowledge. Since then, the pairing of photography and science has evolved considerably. Photography has positioned itself not only as an effective means of collecting data, but also as a tool for sharing scie

Hybridization is one of the most fundamental quantum mechanical phenomena, with the text book example of binding two hydrogen atoms in a hydrogen molecule. Here we report tunnel spectroscopy experiments illustrating the hybridization of another type of discrete quantum states, namely of superconducting subgap states that form in segments of a semiconducting nanowire in contact with superconducting

Film screening

Introduction: Most studies determining speakers’ perceived gender as binarily female or male are reliant on F0 perception, although other vocal parameters may also contribute to the perception of gender. The current study focused on the impact of breathiness on the perception of speakers’ gender as a biological variable (feminine or masculine). Methods: n = 31 normal hearing, native English speake

After the atomic bombing in Hiroshima, a radio station was the first to inform the public about the terrible incident. It was the Tokyo radio which said that “practically all living things, human and animal, were literally seared to death,”Functioning site-specifically and drawing upon the architectural structure of the building, the installations explore the relationship between sound and space b

Recently there has been an increase in the number of available autonomous vehicle (AV) models. To evaluate and compare the safety of the various models the AVs need to be tested in several diverse safety-critical scenarios. We propose the Adversarial Test Case Generator (ATCG) that differently from previous test case generators allows for the generation of realistic collision scenarios with varied

Bark beetles (Curculionidae: Scolytinae) spend most of their life in tissues of host plants, with several species representing economically relevant pests. Their behaviour is largely guided by complex olfactory cues. The compound verbenone was discovered early in the history of bark beetle pheromone research and is now sometimes referred to as a ‘universal bark beetle repellent’. However, some stu

Higher education institutions are struggling to elevate the value and status of academic teaching. In this endeavour, rewards for excellence in teaching are becoming a common measure. This study reports on the experience of the first academic teachers who were given the status as rewarded teachers in new reward systems. We explore rewarded teachers’ potential to influence teaching and learning cul

IASPIS är Konstnärsnämndens internationella program inom bild- och formområdet. Det riktar sig till dig som är yrkesverksam konstnär inom bild- och formområdet och har en konstnärlig praktik inom exempelvis bildkonst, fotografi, formgivning, konsthantverk, design, illustration, textilkonst eller arkitektur.

Extracorporeal membrane oxygenation (ECMO) is a last resort therapy for patients with respiratory failure where the gas exchange capacity of the lung is compromised. Venous blood is pumped through an oxygenation unit outside of the body where oxygen diffusion into the blood takes place in parallel to carbon dioxide removal. ECMO is an expensive therapy which requires special expertise to perform.

Objective: The current study examined whether bullyingvictimization was associated with bringing a weapon toschool, fully or partly mediated by feeling unsafe in school,negative future education orientation, and skipping school.Method: Data from 6199 students (12–18 years old), whohad filled out the 2017 School Crime Supplement to theNational Crime Victimization Survey, were analyzed.Results: The ObjectiveThe current study examined whether bullying victimization was associated with bringing a weapon to school, fully or partly mediated by feeling unsafe in school, negative future education orientation, and skipping school.MethodData from 6199 students (12–18 years old), who had filled out the 2017 School Crime Supplement to the National Crime Victimization Survey, were analyzed.ResultsThe r

A 1-m normal-incidence monochromator has been designed and installed on a bending-magnet beam line at the MAX storage ring in Lund. The optical properties of the beam line have been investigated via ray-tracing studies and with flux measurements of the beam line-monochromator combination. A resolution of 0.9 Å at 919.8 Å was measured in first-order diffraction with an argon hollow-cathode lamp forA 1-m normal-incidence monochromator has been designed and installed on a bending-magnet beam line at the MAX storage ring in Lund. The optical properties of the beam line have been investigated via ray-tracing studies and with flux measurements of the beam line-monochromator combination. A resolution of 0.9 Å at 919.8 Å was measured in first-order diffraction with an argon hollow-cathode lamp for