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University spin-offs and triple helix dynamics in regional innovation ecosystems: A comparison of technology intensive start-ups in Sweden

This study offers novel insights into how university spin-offs contribute to triple helix dynamics and the evolutionary processes of industrial renewal in regional innovation ecosystems. We analyse three groups of technology intensive start-ups: university spin-offs, corporate spin-offs, and independent technology start-ups. We compare and analyse various characteristics, functions, and processes

The confluence of Cloud computing, 5G, and IoT in the Fog

In the wake of the arrival of cloud computing, future applications are poised to become more resilient and adaptive by embracing elasticity in an osmotic manner. Although cloud computing is a strong attractor for application developers, thereare still unconquered performance frontiers. Latency-sensitive and missioncritical applications make up a significant portion of all software systems, and the

Health-related quality of life in children with Type 1 diabetes: an RCT of hospital-based care and hospital-based home care at diagnosis

Introduction: When a child is diagnosed with Type 1 diabetes, it involves extensive lifestyle changes for the whole family. There is limited knowledge of the impact the initial care has for children and parents over time. The aim was to compare children’s diabetes-specific health-related quality of life (HRQOL) in hospital-based care and hospital-based home care (HBHC), 12 and 24 months after the

Crystal structure and substrate interactions of an unusual fungal non-CBM carrying GH26 endo-β-mannanase from Yunnania penicillata

Endo-β(1 → 4)-mannanases (endomannanases) catalyse degradation of β-mannans, an abundant class of plant polysaccharides. This study investigates structural features and substrate binding of YpenMan26A, a non-CBM carrying endomannanase from Yunnania penicillata. Structural and sequence comparisons to other fungal family GH26 endomannanases showed high sequence similarities and conserved binding res

Modeled aerosol-cloud indirect effects and processes based on an observed partially glaciated marine deep convective cloud case

A tropical maritime case of deep convective clouds was studied using a state-of-the-art aerosol-cloud model in order to evaluate the microphysical mechanisms of aerosol indirect effects (AIE). The aerosol-cloud scheme used is a hybrid bin/bulk model, which treats all phases of clouds and precipitation allowing a detailed analysis of process-level aerosol indirect effects on targeted cloud types.

Reversible Formation of Thermoresponsive Binary Particle Gels with Tunable Structural and Mechanical Properties

We investigate the collective behavior of suspended thermoresponsive microgels that expel solvent and subsequently decrease in size upon heating. Using a binary mixture of differently thermoresponsive microgels, we demonstrate how distinctly different gel structures form, depending on the heating profile used. Confocal laser scanning microscopy (CLSM) imaging shows that slow heating ramps yield a

Neutralization of Interleukin-1β following Diffuse Traumatic Brain Injury in the Mouse Attenuates the Loss of Mature Oligodendrocytes

Traumatic brain injury (TBI) commonly results in injury to the components of the white matter tracts, causing post-injury cognitive deficits. The myelin-producing oligodendrocytes (OLs) are vulnerable to TBI, although may potentially be replaced by proliferating oligodendrocyte progenitor cells (OPCs). The cytokine interleukin-1β (IL-1β) is a key mediator of the complex inflammatory response, and

From molecule to man : Integrating molecular biology with whole organ physiology in studying respiratory disease

Chronic lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), and idiopathic pulmonary fibrosis (IPF) are all characterized by structural changes of the airways and/or lungs that limit airflow and/or gas exchange. Currently, there is no therapy available that adequately targets the structural remodeling of the airways and lungs in these diseases. This underscores the great ne

The impact of goal based communication on policy acceptance

According to the International Energy Agency about 14% of greenhouse gases (GHG) are generated by the transportation sector globally and this share is estimated to increase to 50% by 2030. At the same time consumption of mobility is continuously increasing, making it one of the most crucial sectors to focus on for sustainable consumption. Several measures and policies are being implemented to redu