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Considerations and methods for placebo controls in surgical trials (ASPIRE guidelines)

Placebo comparisons are increasingly being considered for randomised trials assessing the efficacy of surgical interventions. The aim of this Review is to provide a summary of knowledge on placebo controls in surgical trials. A placebo control is a complex type of comparison group in the surgical setting and, although powerful, presents many challenges. This Review outlines what a placebo control

Mushroom body evolution demonstrates homology and divergence across Pancrustacea

Descriptions of crustacean brains have focused mainly on three highly derived lineages of malacostracans: the reptantian infraorders represented by spiny lobsters, lobsters, and crayfish. Those descriptions advocate the view that dome- or cap-like neuropils, referred to as 'hemiellipsoid bodies,' are the ground pattern organization of centers that are comparable to insect mushroom bodies in proces

A content analysis of environmentally sustainable logistics - A complexity outlook

Purpose of this paper The purpose of this article is to explore themes and challenges in making logistics environmentally sustainable with a complexity theoretical perspective. Design/methodology/approach The research is explorative and based on a cross-sectional design focusing on different entities of supply chains. The study set out with a systematic review and content analysis of articles in

Pedagogical Agents: Pedagogical Interventions via Integration of Task-oriented and Socially Oriented Conversation

A main objective of the research is to develop an educational math game based on the pedagogies of learning by teaching (Bargh & Schul, 1980) , peer coaching and social role models (Bandura1986, 2000; Schunk, 1987) while exploiting a tight interrelation of task oriented and socially oriented conversation. Another objective is to use the game to explore the mentioned pedagogical topics via desi

Interested, indifferent or active information avoider of climate labels: Cognitive dissonance and ascription of responsibility as motivating factors

Active avoidance of information is gaining attention in behavioral sciences, and recently also its’ relevance from an economic theory perspective. We explore motivations and policy implications of active avoidance of carbon emission information. In a stated preference survey respondents were asked to indicate if they wished to access carbon emission information (info-takers) or not (info-decliners

Using four different clinical tools as predictors for pain after total hip arthroplasty : A prospective cohort study

Background: Treatment of postoperative pain remains a significant clinical problem, and prediction of patients with a risk of higher postoperative pain levels is an important focus. We aimed to identify patients undergoing total hip arthroplasty (THA) with risk of higher pain levels at 24 h postoperatively by using four simple and easily available clinical tools. Methods: This prospective observat

Transcriptomic resources for evolutionary studies in flat periwinkles and related species

The flat periwinkles, Littorina fabalis and L. obtusata, comprise two sister gastropod species that have an enormous potential to elucidate the mechanisms involved in ecological speciation in the marine realm. However, the molecular resources currently available for these species are still scarce. In order to circumvent this limitation, we used RNA-seq data to characterize the transcriptome of fou