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A simple and reproducible model for the experimental study of the normally functioning human appendix is described. The appendix removed from a human is transplanted into a nude mouse and is kept vital for at least 4 hours. This model is an improvement on previous models. It corresponds well with the working of the normal human appendix as regards tissue type and characteristics. Results are easil
In an experimental model using the human appendix transplanted into the Rowett rat, the role of obstruction in the pathogenesis of acute appendicitis was studied. Nine animals were anaesthetized and underwent laparotomy. Normal human appendices, removed during routine surgery, were transplanted into the rats. The appendices were obstructed by a balloon catheter introduced through the open end. Pre
Between 1969 and 1984 65 children were operated on for testicular torsion. A follow-up study of 63 patients who underwent surgery for unilateral testicular torsion with fixation only on the affected side showed that no torsion occurred on the opposite nonfixated side and there was no retorsion during an observation period of an average of more than seven years. From our calculated risk for contral
The value of bacteriologic findings in patients with acute appendicitis was studied. Routine urinary culture specimens were taken preoperatively from 194 children (mean age 11±3 years) undergoing emergency appendectomy. Bacteria were found in culture specimens of urine from 26 of 156 patients with acute appendicitis. The bacteriuria was correlated to the position of the appendix, the duration of d
A follow-up study of 12 patients who had undergone Stephens rectoplasty for high imperforate anus is presented. Clinical assessment and anal electromyography were performed more than 7 years after surgery, both before and after a year's physiotherapeutic training of the perianal musculature. Electromyography showed correlation between faecal continence and tonus of the anal sphincter, the anocutan
At present our knowledge of enteric peptide-containing neurons in man is limited. In this study we have used human appendices removed at surgery to examine the peptidergic innervation by immunocytochemistry, immunochemistry, and pharmacological in vitro experiments. Immunocytochemistry revealed a variety of peptide-containing nerve fiber populations in the human appendix. VIP/PHI-, VIP/PHI/NPY-, S
Computed tomography (CT) was performed in 9 patients with faecal incontinence more than 8 years after rectoplasty for high imperforate anus. The radiologic findings were correlated with the clinical evaluation of faecal incontinence. No statistically significant correlation was found between function and anatomic findings as demonstrated by CT. Thus, although CT demonstrates the post-operative ana
Computerised tomography and magnetic resonance tomography were performed in nine faecally incontinent patients more than eight years after rectoplasty for high imperforate anus. No statistically significant correlation was found between function, i. e. degree of faecal incontinence, and anatomical findings. Thus, in spite of a detailed demonstration of the post-operative anatomy, the information d
This paper reports on two cases of incarcerated congenital diaphragmatic hernia presenting as intestinal obstruction without any signs or symptoms or respiratory tract illness.
Open testicular wedge biopsy has electively been performed prior to completion of maintenance therapy for acute lymphoblastic leukemia. 25 boys during 6 years were included in this prospective study. Three boys developed testicular enlargement while on maintenance therapy and biopsies confirmed testicular leukemia. The remaining 22 boys were biopsied at termination of maintenance therapy. Occult t
Domestic social capabilities are a set of national characteristics for understanding why some countries grow faster than others. Yet there is no clear agreement on the main characteristics of these capabilities and therefore they have been neglected in the income convergence debate. The paper presents an index for revisiting the role of social capabilities in this debate. A relatively socially adv
In this paper, we inductively explore how within-firm goal conflict influences inter-firm collaboration over time. Based on our findings, we challenge current theorizing on collaborative dynamics in inter-organizational relationships, positioning firms as polilithic entities, where within-firm goal conflict can spur complex and unexpected between-firm collaborative processes and outcomes.
Today's IT organizations must ensure that IT services are aligned to business needs and actively support ongoing business processes. This means that internal IT service management processes are under constant improvement. However, to be able to know if the IT service provision develops in the right direction, there is a need to perform some kind of self-assessment of IT process maturity. In this p
It is clear that the formal inclusion of the national parliament as a political actor within the EU decision-making process has been one of the most important innovations of the Lisbon Treaty.Their role, however, remains controversial. It is on the one hand disputed whether national parliaments enjoy sufficient powers to tame'competence creep’. On the other hand, it is contested to what extent it
Flying insects are of utmost importance in ecology and for human living conditions. Certain species serve as indispensable pollinators to ensure the availability of food stuffs, while others are dangerous vectors for spreading deadly diseases, such as malaria. Agricultural pests reduce the yield of crops, and their abatement through pesticides cause many additional problems. Birds and bats are fre
The human host defense peptide LL-37 possesses antimicrobial activity but also affects host cell function and viability. Mast cells are involved in innate immunity but no data have been presented on effects of LL-37 on human mast cell viability and export of nucleic acids. Here, we demonstrated by immunofluorescence microscopy that synthesized LL-37 was internalized by human LAD2 mast cells and de
