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Modelling natural disturbances in forest ecosystems: a review

Natural disturbances play a key role in ecosystem dynamics and are important factors for sustainable forest ecosystem management. Quantitative models are frequently employed to tackle the complexities associated with disturbance processes. Here we review the wide variety of approaches to modelling natural disturbances in forest ecosystems, addressing the full spectrum of disturbance modelling from

Enhanced stability of laser wakefield acceleration using dielectric capillary tubes

The stability of beams of laser wakefield accelerated electrons in dielectric capillary tubes is experimentally investigated. These beams are found to be more stable in charge and pointing than the corresponding beams of electrons accelerated in a gas jet. Electron beams with an average charge of 43 pC and a standard deviation of 14% are generated. The fluctuations in charge are partly correlated

Cardiac cell identification and isolation

Identification and isolation of cardiomyocytes from the heart, embryonic stem cells, or induced pluripotent stem cells is a challenging task and will require specific isolation techniques. Less than 30% of the cells within the murine heart are cardiomyocytes and, what is more, there are multiple sub-populations of cardiomyocytes like atrial, ventricular and conduction system cardiomyocytes. In Pap

Global importance, patterns, and controls of dissolved silica retention in lakes and reservoirs

Lentic water bodies (lakes and reservoirs) offer favorable conditions for silica (SiO2) burial in sediments. Recent global estimates suggest that (1) lentic SiO2 trapping is a globally important SiO2 flux, and (2) through reservoir construction, humans have dramatically altered river dissolved SiO2 (DSi) transport and coastal DSi delivery. However, regional to global scale patterns and controls of

Effects of turbidity and an invasive waterweed on predation by introduced largemouth bass

Anthropogenic activities lead to changes in characteristics of aquatic ecosystems, including alteration of turbidity and addition of invasive species. In this study, we tested how changes in turbidity and the recent invasion of an aquatic macrophyte, Egeria densa, may have changed the predation pressure by introduced largemouth bass on juvenile striped bass and delta smelt, two species that have s

Computational Analysis of Pin-Fin Arrays Effects on Internal Heat Transfer Enhancement of a Blade Tip Wall

Cooling methods are strongly needed for the turbine blade tips to ensure a long durability and safe operation. Improving the internal convective cooling is therefore required to increase the blade tip life. A common way to cool the tip is to use serpentine passages with 180-deg turns under the blade tip cap. In this paper, enhanced heat transfer of a blade tip cap has been investigated numerically

Introducing multiple treatment plan-based comparison to investigate the performance of gantry angle optimisation (GAO) in IMRT for head and neck cancer

Background and purpose. The purpose of this study was to evaluate the performance of gantry angle optimisation (GAO) compared to equidistant beam geometry for two inverse treatment planning systems (TPSs) by utilising the information obtained from a range of treatment plans. Material and methods. The comparison was based on treatment plans generated for four different head and neck (H&N) cance

Therapeutic opportunities of alpha-1-microglobulin A study in placenta, blood, skin and eye

This thesis describes functional studies of the human protein alpha-1-microglobulin (A1M), with the aim of exploring its usefulness as a therapeutic agent in diseases where oxidative stress is a prominent feature. A1M is a 26 kDa plasma and tissue protein with reductase activity and radical- and heme-binding antioxidative functions. The research focus in this thesis has been to study the in vivo p

Human Anti-Oxidation Protein A1M-A Potential Kidney Protection Agent in Peptide Receptor Radionuclide Therapy.

Peptide receptor radionuclide therapy (PRRT) has been in clinical use for 15 years to treat metastatic neuroendocrine tumors. PRRT is limited by reabsorption and retention of the administered radiolabeled somatostatin analogues in the proximal tubule. Consequently, it is essential to develop and employ methods to protect the kidneys during PRRT. Today, infusion of positively charged amino acids is

Quadrupole moments of collective structures up to spin similar to 65(h)over-bar in Er-157 and Er-158: A challenge for understanding triaxiality in nuclei

The transition quadrupole moments. Q(t), of four weakly populated collective bands up to spin similar to 65h in Er-157,Er-158 have been measured to be similar to II eb demonstrating that these sequences are associated with large deformations. However, the data are inconsistent with calculated values from cranked Nilsson-Strutinsky calculations that predict the lowest energy triaxial shape to be as

Comparison of geoelectrical imaging and tunnel documentation at the Hallandsas Tunnel, Sweden

For construction in rock a thorough pre-investigation is important in order to avoid unforeseen conditions which may delay the work. It is crucial to remember the results from this investigation in the further work, and use the experience from the construction to update the geological prognosis and reduce the uncertainties. Different geophysical methods have proved valuable tools in such investiga

Contextual inquiry and socio-technical practice

Purpose: During discussions at the ASC 2013 Conference, we were stimulated to consider acting,learning and understanding in the context of organizational change, and in particular the relationship between organizational actors and external analysts. This article therefore seeks to review from a cybernetic perspective how a socio-technical toolbox can help to facilitate organisational change, and t

A snapshot into the terrestrial ecosystem of an exceptionally well-preserved dinosaur (Hadrosauridae) from the Upper Cretaceous of North Dakota, USA

A palynological investigation of sedimentary rocks enclosing an exceptionally well-preserved fossil dinosaur (Hadrosauridae) discovered in the upper part of the Hell Creek Formation in south western North Dakota was conducted in order to document the immediate paleoenvironment of this dinosaur. The specimen, an Edmontosaurus annectens is remarkable in having exceptional three-dimensional preservat

Joint Bayesian Positioning and Multipath Mitigation in GNSS

A sequential Bayesian estimation algorithm for joint positioning and multipath mitigation within satellite navigation receivers is presented. The underlying process model is especially designed for dynamic user scenarios and dynamic channel conditions. To demonstrate its capabilities simulation results are presented.

Chemogenetics, Induced Neurons and Pluripotent Stem Cells: Towards Advanced Gene and Cell Therapies Targeting Epilepsy

The complexity of the central nervous system and existence of the blood-brain barrier often causes difficulties for traditional pharmacological treatments of neurological diseases. This thesis explores the feasibility and potential for novel gene and cell therapy approaches, which hold better promise for neurological disorders, while particularly targeting epilepsy. Epilepsy is a multifactorial ne

An urn model for odds ratio based adaptive phase III clinical trials

We study the limiting behaviour of a generalized Polya urn, motivated by adaptive data-dependent allocation designs, which are used in Phase III clinical trials in order to allocate a larger number of patients to the better treatment. We establish rigorous limiting results for the model, including the Central Limit Theorem, thus providing the theoretical background for using the odds ratio-based a