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alpha-ketoglutarate (AKG) absorption from pig intestine and plasma pharmacokinetics

To study the absorption, metabolism and kinetics, the AKG ( in different concentrations) was administered intravenously, intra-portally, orally and directly into the ileum or duodenum of pigs, chronically fitted with portal and jugular catheters and T-shaped cannula at the duodenum and ileum. Additionally, this study was conducted to determine the influence of low pH, Fe2+ or/ and SO42- on AKG gut

Microcalorimetric measurements of metabolic activity of six decay fungi on spruce wood as a function of temperature

Microcalorimetry, i.e., the measurement of heat production rate was used to assess the metabolic activity of six wood-decay fungi growing on moist wood particles as a function of the temperature. Four brown-rot fungi increased their activity with increasing temperature in the temperature range 5-35 C, and one brown-rot and the white-rot fungus had a lower activity at 35 C than at 25 C. It may be p

On language production in severe developmental language disorders and the concept of linguistic levels. A longitudinal study of ten children with severe development language disorders

On the basis of a neurolinguistic assessment procedure (Holmberg and Sahlen, 1986) ten children with severe and specific developmental language disorders (DLD) were studied over a four-year period. Initially they all showed global language problems which, in the course of development, became more specific. Although there were considerable differences in the neurolinguistic profiles, some general p

Övertändning, backdraft och brandgasexplosion sett ur räddningstjänstens perspektiv

This report presents a detailed description of the phenomena flashover, backdraft and smoke gas explosion. The physical and chemical processes which are involved in these phenomena are thoroughly discussed. The report also describes a number of compartment fire scenarios which are believed to be the most common scenarios occurring in Sweden. The description is based on a number of full- scale exp

Antigen-binding sites dominate the surface properties of IgG antibodies

A new technique, liquid-liquid partition chromatography in an aqueous polyethylene glycol-dextran two-phase system, was used to detect differences in surface properties of antibodies with different antigen-binding sites. Employing well-characterized monoclonal IgG antibodies and Fab and Fc fragments thereof as well as chimeric IgG antibodies we found a remarkable relationship between structure of

A very short uranium-uranium bond: The predicted metastable U-2(2+)

Quantum chemical calculations, based on multiconfigurational wave functions and including relativistic effects, show that the U-2(2+) system has a large number of low-lying electronic states with S of 0 to 2 and Lambda ranging from zero to ten. These states share a very small bond length of about 2.30 angstrom, compared to 2.43 angstrom in neutral U-2. The Coulomb explosion to 2 U+ lowers the ener

Recordings of mucociliary activity in vivo: benefit of fast Fourier transformation of the photoelectric signal

Investigations of mucociliary activity in vivo are based on photoelectric recordings of light reflections from the mucosa. The alterations in light intensity produced by the beating cilia are picked up by a photodetector and converted to photoelectric signals. The optimal processing of these signals is not known, but in vitro recordings have been reported to benefit from fast Fourier transformatio

Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities

Matrilins are putative adaptor proteins of the extracellular matrix (ECM) which can form both collagen-dependent and collagen-independent filamentous networks. While all known matrilins (matrilin-1, -2, -3, and -4) are expressed in cartilage, only matrilin-2 and matrilin-4 are abundant in non-skeletal tissues. To clarify the biological role of matrilin-2, we have developed a matrilin-2-deficient m

Serotonin agents in the treatment of acquired brain injury

Background: The development of novel serotonin agents has led to an increased use of these medications throughout medical practice. An understanding of the basic pharmacological function of these agents is key to understanding their usefulness. Among persons with brain injury, serotonin agents have been used for the treatment of depression, panic disorder, obsessive-compulsive disorders, agitation

Inte ens en gång – en tautologisk talspråkskonstruktion.

I sydsvenskt talspråk används ofta den tautologiska konstruktionstypen ens en gång i stället för ens för att uttrycka emfas i förbindelse med negation. Det negativa polaritetsordet ens har tidigare undersökts i förbindelse med negationen inte (Waldmann 2002). Det visar sig i den studien att realisationen kan beskrivas utifrån Chomsky (1999). I de sydsvenska dialekterna verkar däremot konstruktione

Immune complexes, rheumatoid factors, and cellular immunological parameters in patients with giant cell arteritis

Circulating immune complexes were found in 2 of 15 patients with giant cell arteritis (GCA) by using a solid phase Clq enzyme linked immunoabsorbent assay (ELISA). The prevalence in controls was 5%. Rheumatoid factor could be demonstrated in 2 out of 27 patients and in 11% of the controls by using a similar ELISA technique. The prevalence of T cells in blood was similar in 25 patients with GCA and

Swedish men's experiences of becoming fathers to their preterm infants

PURPOSE: To describe Swedish men's experiences of becoming fathers to their preterm infants. DESIGN: A cross-sectional descriptive study. SAMPLE AND METHOD: Eight men participated in semistructured interviews with open-ended questions. The interviews were analyzed using manifest and latent content analysis. MAIN OUTCOME VARIABLES: The concepts of control and noncontrol. RESULT: The manifest analys