The most malignant brain tumour, glioblastoma multiforme (GBM), has an utterly bad prognosis. In spite of all available therapy, the mean survival time is less than a year. In the unique BRIGTT project (Brain Immuno Gene Tumour Therapy), patients at the Dept of Neurosurgery. Lund University Hospital, are immunised with their own glioma cells, which have been transfected with the immunostimulatory

The development of inflammatory bowel diseases (IBD) and colon cancer (CC) has been shown to involve the up-regulation of inflammatory mediators and the machinery producing them such as the eicosanoids. Changes in the expression of extracellular matrix proteins and their related integrin receptors have also been shown to be important in the advancement IBD and CC. In light of this, we have investi

In 2001, multi-family dwellings were built at nine properties in Västra hamnen, Malmö, Sweden. Several well known Swedish architects were involved in designing the buildings, hence they reflect modern architecture. Prior to the inauguration, the buildings were displayed at the international housing exhibition Bo01. The housing exhibition had an ecological and sustainability focus. Regarding energy

The pine sawfly, Diprion jingyuanensis Xiao et Zhang, is a serious pest of Chinese pine (Pinus tabulaeformis Carr.) in the northern parts of China. The general biology of this recently described sawfly species is little known and in the present study we used a synthetic pheromone to monitor its flight period and to evaluate the possibility to use pheromone traps as a tool for estimating and predic

Silver recovery from photographic fixing solutions is investigated by applying solvent extraction techniques. Amines were shown to be the most promising extractants and quaternary ammonium chlorides selected for further studies because of high distribution coefficients and low pH-sensitivity. The distribution coefficient for silver from a 0.5 M ammonium thiosulphate solution increases from 2.3 to

I denna artikel beskrivs hur de kanadensiska mi’kmaqindianerna bearbetar problem som härstammar från tiden i Shubenacadie Residential School. Fastän den stora internatskolan idag är nedlagd fortsätter den att sätta spår i de moderna reservatsbornas liv. Artikelmaterialet hämtas bland annat från ett fältarbete (2000) på ön Cape Breton, Nova Scotia. För att det kanadensiska majoritetssamhället ska f

Bacillus subtilis ferrochelatase is encoded by the hemH gene of the hemEHY gene cluster and catalyses the incorporation of Fe2+ into protoporphyrin IX. B. subtilis ferrochelatase produced in Escherichia coli was purified. It was found to be a monomeric, water-soluble enzyme of molecular mass 35 kDa which in addition to Fe2+ can incorporate Zn2+ and Cu2+ into protoporphyrin IX. Chemical modificatio

OBJECTIVE: To examine the endometrial expression pattern of messenger RNA (mRNA) for selected matrix metalloproteinases (MMP) and tissue inhibitor of metalloproteinases-1 (TIMP-1). DESIGN: Experimental study. SETTING: Department of Obstetrics and gynecology of the Palacky University Medical School and University Hospital, Olomouc, Czech Republic, Department of Obsterics and Gynecology, University

En recension av Mats Jacobssons doktorsavhandling om bob Dylans texter.

Neural transplantation is an experimental treatment for Parkinson's disease. Widespread clinical application of the grafting technique is hampered by a relatively poor survival (around 10%) of implanted embryonic dopamine neurones. Earlier animal studies have indicated that a large proportion of the grafted cells die during graft tissue preparation and within the first few days after intracerebral

Background. Ethical issues arise in many obstetric situations and demand constant consideration by obstetricians. The aim of this study was to highlight the meaning of being in an ethically difficult situation as narrated by obstetricians. Methods. A descriptive design with a qualitative approach using a hermeneutic phenomenological method for analysis. Interviews were performed with 14 obstetric