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A Research Agenda for Sustainable Cities and Communities

Global in its outlook, this Research Agenda systematically reviews and critiques existing research on sustainable cities, calling for greater engagement with a diversity of perspectives. It interrogates foundational assumptions in the field and offers reframed perspectives on sustainability. Chapters also explore diverse approaches, actors and domains, locating emerging dynamics and new directions

DDPC : Automated Data-Driven Power-Performance Controller Design on-the-fly for Latency-sensitive Web Services

Traditional power reduction techniques such as DVFS or RAPL are challenging to use with web services because they significantly affect the services' latency and throughput. Previous work suggested the use of controllers based on control theory or machine learning to reduce performance degradation under constrained power. However, generating these controllers is challenging as every web service app

GATA2 at the mitosis-to-G1 transition is critical for definitive hematopoiesis

In mitosis, transcription factors (TFs) and RNA polymerase disperse across the cytoplasm leading to transcriptional silencing, but some TFs are retained on condensed chromatin and mark genomic sites, a mechanism termed mitotic bookmarking. In pluripotent and differentiated cells this mechanism is important for pluripotency maintenance, cell reprogramming and lineage inheritance. However, the role

The ST22 chronology for the Skytrain Ice Rise ice core - Part 2 : An age model to the last interglacial and disturbed deep stratigraphy

We present an age model for the 651g€¯m deep ice core from Skytrain Ice Rise, situated inland of the Ronne Ice Shelf, Antarctica. The top 2000 years have previously been dated using age markers interpolated through annual layer counting. Below this, we align the Skytrain core to the AICC2012 age model using tie points in the ice and air phase, and we apply the Paleochrono program to obtain the bes

Overview : The Baltic Earth Assessment Reports (BEAR)

Baltic Earth is an independent research network of scientists from all Baltic Sea countries that promotes regional Earth system research. Within the framework of this network, the Baltic Earth Assessment Reports (BEARs) were produced in the period 2019-2022. These are a collection of 10 review articles summarising current knowledge on the environmental and climatic state of the Earth system in the

Long-term changes of nitrogen leaching and the contributions of terrestrial nutrient sources to lake eutrophication dynamics on the Yangtze Plain of China

Over the past half-century, drastically increased chemical fertilizers have entered agricultural ecosystems to promote crop production on the Yangtze Plain, potentially enhancing agricultural nutrient sources for eutrophication in freshwater ecosystems. However, long-term trends of nitrogen dynamics in terrestrial ecosystems and their impacts on eutrophication changes in this region remain poorly

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Recent electoral victories by left-leaning leaders and parties mark another turn in the oscillations of Latin American politics, but they also signal enduring changes. The electoral success of the left is a sign of both the durability of electoral democracy and the persistence of social pres-sures in highly unequal societies. In this article, we discuss how the electoral fates and governing strate

Uncovering the cytotoxic effects of air pollution with multi-modal imaging of in vitro respiratory models

Annually, an estimated seven million deaths are linked to exposure to airborne pollutants. Despite extensive epidemiological evidence supporting clear associations between poor air quality and a range of short- and long-term health effects, there are considerable gaps in our understanding of the specific mechanisms by which pollutant exposure induces adverse biological responses at the cellular an

The chemical characterization of halo substructure in the Milky Way based on APOGEE

Galactic haloes in a Λ-CDM universe are predicted to host today a swarm of debris resulting from cannibalized dwarf galaxies. The chemodynamical information recorded in their stellar populations helps elucidate their nature, constraining the assembly history of the Galaxy. Using data from APOGEE and Gaia, we examine the chemical properties of various halo substructures, considering elements that s

A nutritional biomarker score of the Mediterranean diet and incident type 2 diabetes : Integrated analysis of data from the MedLey randomised controlled trial and the EPIC-InterAct case-cohort study

Background AU Self-reported: Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly adherence to the Mediterranean diet has been: modestly inversely associated with incidence of type 2 diabetes (T2D) in cohort studies. There is uncertainty about the validity and magnitude of this association due to subjective reporting of diet. The association has not been evaluated using an objectively measured

CONTRASTS OF REGISTER UNDERLIE THE PERCEPTION OF MUSICAL HUMOR

IN THE PSYCHOLOGICAL LITERATURE ON MUSICAL humor, the emphasis on laughter-inducing music has naturally led researchers to focus on quite uncommon devices, such as stylistic deviations or formal incongruities that strongly violate listeners' expectations, as the privileged basis for musical humor. But musical humor extends well beyond laughter-inducing music. It is also a kind of semantic content

Precise dd excitations and commensurate intersite Coulomb interactions in the dissimilar cuprates YBa2Cu3 O7-y and La2-xSrxCu O4

Using high-resolution extreme ultraviolet resonant inelastic x-ray scattering (EUVRIXS) spectroscopy at the Cu M-edge, we observed doping dependent spectral shifts of interorbital (dd) excitations of YBa2Cu3O7-y and La2-xSrxCuO4. With increasing the hole doping level from undoped to optimally doped superconducting compositions, the leading edge of dd excitations is found to shift towards lower ene

A hypothesis for robust polarization vision : an example from the Australian imperial blue butterfly, Jalmenus evagoras

The Australian lycaenid butterfly Jalmenus evagoras has iridescent wings that are sexually dimorphic, spectrally and in their degree of polarization, suggesting that these properties are likely to be important in mate recognition. We first describe the results of a field experiment showing that free-flying individuals of J. evagoras discriminate between visual stimuli that vary in polarization con

Pressure-induced charge-transfer and structural transition in hexagonal multiferroic HoMnO3

The structural properties of the hexagonal multiferroic h-HoMnO3 under high pressure have been explored using synchrotron x-ray diffraction and x-ray absorption spectroscopy in diamond anvil cells. The structure was found to undergo a pressure-induced phase transition at ∼24 GPa to a rhombohedrally distorted superstructure, which is isostructural to the oxygen-loaded h-RMnO3+δ (R=Y,Dy,Ho,Er; δ≈0.2

Large eddy simulations of fully developed turbulent flows over additively manufactured rough surfaces

In the last decade, with the growing demand for efficient and more sustainable products that reduce our CO2 footprint, progresses in Additive Manufacturing (AM) have paved the way for optimized heat exchangers, whose disruptive design will heavily depend on predictive numerical simulations. Typical AM rough surfaces show limited resemblance to the artificially constructed rough surfaces that have

Comet Assay Profiling of FLASH-Induced Damage : Mechanistic Insights into the Effects of FLASH Irradiation

Numerous studies have demonstrated the normal tissue-sparing effects of ultra-high dose rate ‘FLASH’ irradiation in vivo, with an associated reduction in damage burden being reported in vitro. Towards this, two key radiochemical mechanisms have been proposed: radical–radical recombination (RRR) and transient oxygen depletion (TOD), with both being proposed to lead to reduced levels of induced dama

Thermal phenotypic plasticity of pre-and post-copulatory male harm buffers sexual conflict in wild Drosophila melanogaster

Strong sexual selection frequently leads to sexual conflict and ensuing male harm, whereby males increase their reproductive success at the expense of harming females. Male harm is a widespread evolutionary phenomenon with a strong bearing on population viability. Thus, understanding how it unfolds in the wild is a current priority. Here, we sampled a wild Drosophila melanogaster population and st

Formation of Pyridyl Radicals by Hydrogen Atom Abstraction : Theoretical Study

Abstract: Specific features of the pyridine structure make it a convenient model system to describe coal combustion; however, the main attention of researchers has been paid to the formation of the ortho-pyridyl, whereas the formation of meta- and para-pyridyls has been yet poorly studied. The rate constants of the formation of three pyridyl radicals originating from pyridine by hydrogen atom abst

Experimental oscillator strengths of Al I lines for near-infrared astrophysical spectroscopy

Context. Elemental abundances can be determined from stellar spectra, making it possible to study galactic formation and evolution. Accurate atomic data is essential for the reliable interpretation and modeling of astrophysical spectra. In this work, we perform laboratory studies on neutral aluminium. This element is found, for example, in young, massive stars and it is a key element for tracing o

Comparison of the Chemical Composition of Six Canihua (Chenopodium pallidicaule) Cultivars Associated with Growth Habits and after Dehulling

The canihua (Chenopodium pallidicaule) is a native Andean crop that stands out for its high content of protein, fiber, and minerals and that has a good fatty acid profile. We studied six canihuas cultivars, which were compared according to their proximate, mineral, and fatty acid composition. Based on the form of stems, termed growth habit, they belonged to two groups: decumbent (Lasta Rosada, Ill