Despite marked development in cancer therapies during recent decades, the prognosis for advanced cancer remains poor. The conventional tumor–cell-centric view of cancer can only explain part of cancer progression, and thus a thorough understanding of the tumor microenvironment (TME) is crucial. Among cells within the TME, cancer-associated fibroblasts (CAFs) are attracting attention as a target fo

Aim: This study aimed to investigate changes in mental health among young adults participating in an integrated mental health and vocational support intervention according to the Södertälje Supported Employment and Education model. Design: A prospective longitudinal pre–post intervention study of 12 months. Methods: Instruments on depressive symptoms, quality of life, empowerment, engagement in ac

If resource intensive practices are regularly represented as conventional, these potentially become naturalised and inconspicuous consumption will increase. Understanding how representations, conventions and everyday practices interact is thus fundamental in tackling unsustainable consumption. To gain new insights into how representations, conventions and practices interact, this paper explores ho

Background: The prevalence of heart failure (HF) is rising with ageing population and constitutes a major health problem globally. A common complication of HF is pulmonary hypertension (PH) which negatively impacts survival. A pathophysiological association between HF and PH with tumorigenic processes has been suggested. We aimed to identify the plasma levels of, and the association between tumour

The aim of this study was to explore how consequences from a university-wide partnership unfolded at various levels within a university and induced intra-organizational dynamics. This was achieved via an in-depth investigation of “The Bridge,” a collaborative partnership between the young mid-range Swedish Linnaeus University (“Average Joe”) and the home furnishing retail giant IKEA, which despite

Raptors have always fascinated mankind, owls for their highly sensitive vision, and eagles for their high visual acuity. We summarize what is presently known about the eyes as well as the visual abilities of these birds, and point out knowledge gaps. We discuss visual fields, eye movements, accommodation, ocular media transmittance, spectral sensitivity, retinal anatomy and what is known about vis

Growth in the smallholder-based livestock sector, characterized by increasing number of animals, commercialization and processing of animal products have historically provided a decisive contribution to raising the incomes of farm households, and to the broader process of agricultural transformation. In this paper, we use a mixed methods approach to examine the processes of extensive and intensive

CERN operates one of the most complex particle accelerator facilities in the world. Several different hazards, including fires, are present and need to be investigated and reduced to a tolerable level. Toward this goal, CERN aims at developing a catalog containing detailed fire dynamics descriptions of combustible items present in its facilities. This paper contributes to this catalog in two ways.

Infection patterns of avian haemosporidians result from the evolution of their associations with hosts, and can be shaped by multiple biotic factors. However, at the level of parasite species, few studies have investigated the details of the temporal dynamics of infection patterns in wild bird communities. We hereby studied a wild bird community in southern Sweden to investigate two generalist par

Segmented chip morphology has a significant influence on distribution of residual stress and surface topography on machined surface in machining difficult-to-cut materials. In this paper, Coupled Eulerian and Lagrangian (CEL) model is employed to investigate the effect of segmented chip on surface integrity (residual stress distribution and surface topography) in orthogonal machining of Inconel718

Over the last three years, the idea of a ‘post-truth society’ has become a common talking point. Politicians from around the world, from Europe to South America to the United States, have been labelled as ‘post-truth leaders’, with Donald Trump being portrayed as the standard bearer for this new kind of political discourse. This article suggests that post-truth leadership is nothing new. Ever sinc

Background: Cellular rejection is most common 3–6 months after heart transplantation while chronic rejection, that is, cardiac allograft vasculopathy and malignancy are the most common causes of death in heart-transplant recipients beyond the third year after transplantation. However, the heart transplantation recipient’s perceived threat of graft rejection has never been explored. Aim: The aim wa

Purpose: The purpose of this paper is to numerically study the influence of wall conduction on the heat transfer of supercritical n-decane in the active regenerative cooling channels. Design/methodology/approach: A horizontally placed rectangular pipe with a solid zone and another one without a solid zone were used. A drastic variation of thermo-physical properties was emphatically addressed. Afte

Nine participants, representing eight different Swedish fire consultancy firms participated in a Round Robin study where two different cases were simulated with the Fire Dynamics Simulator. The first case included a large open warehouse where the activation of a sprinkler system was to be studied. In the second case time to critical conditions in a theatre was to be calculated. The participants we

Background: Previous research shows that critical constructive feedback, that scaffolds students to improve on tasks, often remains untapped. The paper’s aim is to illuminate at what stages students provided with such feedback drop out of feedback processing. Methods: In our model, students can drop out at any of five stages of feedback processing: (1) noticing, (2) decoding, (3) making sense, (4)

Multiple-input multiple-output (MIMO) is a key enabler for high data rates in mobile communications. However, it is challenging to design MIMO terminal antennas for LTE bands below 1 GHz, due to the conventional chassis offering only one resonant characteristic mode (CM). Recently, it was shown that minor structural changes can yield up to two additional resonant modes for designing two-port MIMO

[N,N-bis(1-methyl-2-benzimidazolyl)methyl-N-(bis-2-pyridylmethyl)amine] (L1) and [N,N-bis(2-quinolylmethyl)-N-bis(2-pyridyl)methylamine] (L2) were employed to prepare CuII and CuI complexes for spectroscopic and structural characterization. [L1CuII(H2O)](NO3)2 and [L2CuII(NO3)]NO3 have Jahn–Teller distorted octahedral geometries and give rise to isotropic EPR spectra in frozen solution. [L1CuI(CH3

Background: Depressive symptoms are common in rheumatic diseases and influence patients’ quality of life. The Patient Health Questionnaire-9 (PHQ-9), which assesses symptoms of depression, is valid in English in patients with systemic sclerosis (SSc). However, the measurement properties of the PHQ-8 (short version of the PHQ-9) have not been evaluated in Swedish patients with SSc. Objective: To in