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Bakvägsidentifiering av forskningsdata baserade på individer - riskbedömning och riskminskande åtgärder

Published 20 June 2023 Att dela forskningsdata som baseras på individer kan medföra olika risker, både för de individer vars data delas och för de organisationer som samlar in och hanterar data. En sådan risk är bakvägsidentifiering. Gustav Nilsonne, domänspecialist vid SND, docent vid Karolinska Institutet och forskare vid Stockholms universitet reder ut begreppet och vad som går att göra för att

https://www.lupop.lu.se/article/bakvagsidentifiering-av-forskningsdata-baserade-pa-individer-riskbedomning-och-riskminskande - 2025-04-17

Postdoktor i lungmedicin och epidemiologi (LU)

Published 18 August 2023 Vi söker en motiverad postdoktoral forskare för att driva och utveckla ett flertal epidemiologiska och kliniska studier, för att undersöka vilka faktorer som bidrar till andnöd i befolkningen och vid olika sjukdomar, hur ansträngningsutlöst andfåddhet kan mätas på ett standardiserat sätt genom kliniska test, samt utveckla metoder för och genomföra fallbaserade kliniska prö

https://www.lupop.lu.se/article/postdoktor-i-lungmedicin-och-epidemiologi-lu - 2025-04-17

Postdoctor in Airway diseases (GU)

Published 18 August 2023 The candidate will be responsible for analyzing and publishing the results in international journals based on the core studies WSAS, COWEST and STELLAR projects. The work also includes to presenting project results at national and international scientific meetings, be responsible for ensuring that the quality of data, data management and analyses of the projects meet the h

https://www.lupop.lu.se/article/postdoctor-airway-diseases-gu - 2025-04-17

National and regional registries for congenital heart diseases: Strengths, weaknesses and opportunities

Published 17 September 2021 Photo: Pixabay / Arek Socha 1) We found 15 national/regional registries of congenital heart disease worldwide. 2) Registry coverage ranged from 25 to 100% of all eligible cases. 3) The best registries contain demographic, clinical, physical, and laboratory data. 4) Regular verification is essential for quality data and valid statistical findings. Read the paper at https

https://www.lupop.lu.se/article/national-and-regional-registries-congenital-heart-diseases-strengths-weaknesses-and-opportunities - 2025-04-17

The Importance of Making Assumptions in Bias Analysis

Published 18 September 2021 Quantitative bias analyses allow researchers to adjust for uncontrolled confounding, given specification of certain bias parameters. When researchers are concerned about unknown confounders, plausible values for these bias parameters will be difficult to specify. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/09000/The_Importance_of_M…

https://www.lupop.lu.se/article/importance-making-assumptions-bias-analysis - 2025-04-17

Validating Acute Myocardial Infarction Diagnoses in National Health Registers for Use as Endpoint in Research: The Tromsø Study

Published 18 September 2021 Photo: Pixabay / Colin Behrens The benefits of using data from national registers as endpoints in epidemiological studies include faster, less resource-intensive access to nationwide data and considerably lower loss to follow-up, compared to manual data collection in a limited geographical area. Read the paper at https://www.dovepress.com/validating-acute-myocardial-inf

https://www.lupop.lu.se/article/validating-acute-myocardial-infarction-diagnoses-national-health-registers-use-endpoint-research - 2025-04-17

Integrating Electronic Health Record, Cancer Registry, and Geospatial Data to Study Lung Cancer in Asian American, Native Hawaiian, and Pacific Islander Ethnic Groups

Published 19 September 2021 The integrative data approach is an effective way to conduct cancer research assessing multilevel factors on cancer outcomes among small populations. Read the paper at https://cebp.aacrjournals.org/content/30/8/1506.long

https://www.lupop.lu.se/article/integrating-electronic-health-record-cancer-registry-and-geospatial-data-study-lung-cancer-asian - 2025-04-17

Esophageal resection in Austria—preparing a national registry

Published 19 September 2021 Photo: Pixabay / www_slon_pics This first publication of the Austrian Society of Esophageal Surgery shows that the outcome of esophageal surgery for cancer in Austria compares well with that of renowned international centers. However, a more comprehensive approach including as many national centers as possible will improve outcome research, offer quality management, and

https://www.lupop.lu.se/article/esophageal-resection-austria-preparing-national-registry - 2025-04-17

Decreased Susceptibility of Marginal Odds Ratios to Finite-sample Bias

Published 20 September 2021 Photo: Pixabay / geralt Parameters representing adjusted treatment effects may be defined marginally or conditionally on covariates. The choice between a marginal or covariate-conditional parameter should be driven by the study question. However, an unappreciated benefit of marginal estimators is a reduction in susceptibility to finite-sample bias relative to the unpena

https://www.lupop.lu.se/article/decreased-susceptibility-marginal-odds-ratios-finite-sample-bias - 2025-04-17

A Survivorship-Period-Cohort Model for Cancer Survival: Application to Liver Cancer in Taiwan, 1997–2016

Published 21 September 2021 Photo: Pixabay / Brian Merrill Monitoring survival in cancer is a common concern for patients, physicians, and public health researchers. The traditional cohort approach for monitoring cancer prognosis has a timeliness problem. In this paper, we propose a survivorship-period-cohort (SPC) model for examining the effects of survivorship, period, and year-of-diagnosis coho

https://www.lupop.lu.se/article/survivorship-period-cohort-model-cancer-survival-application-liver-cancer-taiwan-1997-2016 - 2025-04-17

Matched Versus Unmatched Analysis of Matched Case-Control Studies

Published 22 September 2021 Photo: Pixabay / Ronny Overhate Although the need for addressing matching in the analysis of matched case-control studies is well established, debate remains as to the most appropriate analytical method when matching on at least 1 continuous factor Read the paper at https://academic.oup.com/aje/article/190/9/1859/6162924

https://www.lupop.lu.se/article/matched-versus-unmatched-analysis-matched-case-control-studies - 2025-04-17

Parametric-Regression–Based Causal Mediation Analysis of Binary Outcomes and Binary Mediators: Moving Beyond the Rareness or Commonness of the Outcome

Published 23 September 2021 Photo: Pixabay / Gerd Altmann In the causal mediation framework, several parametric-regression–based approaches have been introduced in the last decade for estimating natural direct and indirect effects. For a binary outcome, a number of proposed estimators use a logistic model and rely on specific assumptions or approximations that may be delicate or not easy to verify

https://www.lupop.lu.se/article/parametric-regression-based-causal-mediation-analysis-binary-outcomes-and-binary-mediators-moving - 2025-04-17

Acceptability of patient reported outcome measures (PROMs) in a cystic fibrosis data registry

Published 23 September 2021 Foto från snd.gu.se Improvements in the treatment of cystic fibrosis (CF) have resulted in longer survival and an increased focus on optimising daily functioning with the condition. Patient- reported outcome measures (PROMs) are valuable tools in evaluating the health- related quality of life of persons with chronic diseases. Read the paper at https://bmjopenrespres.bmj

https://www.lupop.lu.se/article/acceptability-patient-reported-outcome-measures-proms-cystic-fibrosis-data-registry - 2025-04-17