Search results

Filter

Filetype

Your search for "*" yielded 526820 hits

Global Neuromagnetic Cortical Fields Have Non-Zero Velocity

Globally coherent patterns of phase can be obscured by analysis techniques that aggregate brain activity measures across-trials, whether prior to source localization or for estimating inter-areal coherence. We analyzed, at single-trial level, whole head MEG recorded during an observer-triggered apparent motion task. Episodes of globally coherent activity occurred in the delta, theta, alpha and bet

Will the R in R&D at large technology corporations disappear? : The demise of the ‘R’ in corporate R&D: is academia stepping up to the challenge?

The author has as a practitioner in industry for 25 years seen a shift in the attitude to corporateresearch. Previously, most established technology firms had substantial departments doing research.Over the years this has changed, and corporate research not seen as short term profitable hasdecreased.A number of papers indicate that the amount of in-house science in technology corporations isindeed

Corporate strategy in a small open economy : Reducing product diversification while increasing international diversification

This study has investigated the changes in corporate strategy and performance in 20 large Swedish MNC's between 1985, 1994 and 1998. It has found a strong pattern of product focusing, increased internationalisation, and a strong increase in accounting-based performance. This development seems to be contrary to former empirical evidence, that international diversification pays off better for more p

Cure of established, intracerebral rat gliomas induced by therapeutic immunizations with tumor cells and purified APC or adjuvant IFN-gamma treatment

We have previously reported that immunizations with mutagen-induced immunogenic variants of a weakly immunogenic rat glioma could protect against isografts of the original tumor cells. In this study we show that prolonged survival and cures of rats with established gliomas in their brains can be achieved by therapeutic immunizations with tumor cell mutants, combined with in vitro and in vivo inter

Increased proportion of CD8+ tumor responsive T cells after immunization with tum- versus tum+ rat glioma

Previously established immunogenic (tum-) clones of an ENU (ethyl-N-nitrosourea)-induced rat glioma, N32, were compared to the original tumor concerning their capacity to induce T lymphocyte responses after in vivo immunization and in vitro restimulation of responder spleen cells in mixed lymphocyte tumor culture (MLTC) assays. Quite unexpectedly, original N32 (tum+) in vivo primed spleen cells pr

Assessing performance of supply chain risk management programmes : A tentative approach

This exploratory study provides initial directions about how risk management programmes could be assessed in a supply chain setting and discusses how such a measurement system could be designed. Measures are needed both for the management to evaluate the success of actions taken in supply chain risk management, as well as for the (supply chain) risk manager to communicate the value of his work. A

Climatology of new particle formation and corresponding precursors at storm peak laboratory

Thirteen years of measurements of ultrafine (3-10 nm diameter) aerosols are presented from a remote high elevation (3210 m a.s.l.) site in Colorado, Storm Peak Laboratory. Previous work has shown that frequent new particle formation (NPF) occurs regularly at the site (52% of days). This long-term climatology of ultrafine aerosols clearly shows a seasonal dependence on new particle formation at Sto

Gaining hope and self-confidence - An interview study of women's experience of treatment by art therapy for severe fear of childbirth

BACKGROUND: Fear of childbirth is a serious problem that can have negative effects on both women and babies and to date treatment options are limited. The aim of this study was to elucidate the experience of undergoing art therapy in women with severe fear of childbirth.METHOD: Nineteen women residing in Sweden, who had undergone art therapy for severe fear of childbirth, were interviewed during 2

Loving the alien

Miriam Aida, vocals Mats Andersson, guitar Ola Bothzen, percussion Finn Björnulfsson, percussion plays the music of David Bowie.

Refractive error and glaucoma

Purpose: To study the association between refractive error, glaucoma damage and IOP in a large population. Methods: We examined 32,918 citizens of the city of Malmö, Sweden, 57-79 years of age, searching for individuals with undetected glaucoma. Refraction was measured with autorefractors. Glaucoma damage was defined as reproducible visual field defects with the Humphrey Full Threshold 24-2 progra

Age, gender, IOP, refraction and optic disc topography in normal eyes. A cross-sectional study using raster and scanning laser tomography

Purpose: To study the influeuce of age, gender, intraocular pressure and refraction on optic disc topography in normal subjects. Methods: We studied both eyes of 225 healthy subjects between 20 and 80 years of age using raster tomography (Glaucoma-Scope®, Ophthalmic Imaging Systems, Sacramento CA, USA) and scanning laser tomography (Heidelberg Engineering, Heidelberg, Germany). We chose to study c

Prevalence of diabetic retinopathy in relation to age at onset of the diabetes, treatment, duration and glycemic control

To study the frequency of diabetic retinopathy in relation to age at diagnosis, treatment, duration of diabetes and glycemic control as measured by means of HbA(1c) levels, we performed a cross-sectional, register-based study in the Helsingborg area of southern Sweden, comprising 2232 diabetic patients. Of the known diabetic population < 75 years old, approximately 70% were estimated to be include

Conformational polymorphism, stability and aggregation in spider dragline silks proteins

Spider silk is spun in a complex and unique process, thought to depend on a hydrophobic conversion of a predominantly disordered to a β-sheet rich protein structures. To test this hypothesis we monitored the effect of cationic (DOTAC) and anionic (alkyl sulfate) detergents and of (ii) solvent polarity using a series of alcohols on the secondary structure transition in dilute solutions of native sp

Beta-silks : enhancing and controlling aggregation

It appears that fiber-forming proteins are not an exclusive group but that, with appropriate conditions, many proteins can potentially aggregate and form fibrils; though only certain proteins, for example, amyloids and silks, do so under normal physiological conditions. Even so, this suggests a ubiquitous aggregation mechanism in which the protein environment is at least as important as the sequen