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Background: The fractalkine/CX3C chemokine receptor 1 (CX3CR1) pathway has been identified to play an essential role in the chemotaxis of microglia, leukocyte trafficking and microglia/macrophage recruitment. It has also been shown to be important in the regulation of the inflammatory response in the early phase after experimental stroke. The present study was performed to investigate if CX3CR1 de

Developing light-harvesting and photocatalytic molecules made with iron could provide a cost effective, scalable, and environmentally benign path for solar energy conversion. To date these developments have been limited by the sub-picosecond metal-to-ligand charge transfer (MLCT) electronic excited state lifetime of iron based complexes due to spin crossover-the extremely fast intersystem crossing

Measures of functional diversity are expected to predict community responses to land use and environmental change because, in contrast to taxonomic diversity, it is based on species traits rather than their identity. Here, we investigated the impact of landscape homogenisation on plants, butterflies and birds in terms of the proportion of arable field cover in southern Finland at local (0.25 km2)

In this article four new ternary phases of RE7Co2Ge4 (RE = La-Nd) are reported. They were synthesized by a solid-state reaction of the elements at high temperature, and their crystal structures were investigated by single crystal X-ray diffraction data. The isostructural phases crystallize in a new monoclinic structure type, space group P21/c, Z = 4, Pearson code mP52, and Wyckoff sequence e13. Th

Enterprise Resource Planning (ERP) system literature reports few studies with a focus on specificities of an industry analysis. Based on the Technology-Organizational-Environment (TOE) framework and the Resource-Based View (RBV) theory, we present a theoretically developed research model aiming at measuring and examining determinants of ERP use and value and their impact in the Iberian region (Por

The number of ice fragments generated by breakup of large graupel in collisions with small graupel fluctuates randomly owing to fluctuations in relative sizes and densities of colliding graupel particles and the stochastic nature of fracture propagation. This paper investigates the impact of the stochasticity of breakup on ice multiplication. When both the rate of generation of primary ice and the

(Graph Presented) A binder-free and solvent-free pencil-trace electrode with intercalated clay particles (mainly SiO2) is prepared via a simple pencil-drawing process on grinded Cu substrate with rough surface and evaluated as an anode material for lithium-ion battery. The pencil-trace electrode exhibits a high reversible capacity of 672 mA h g-1 at 100 mA g-1 after 100 cycles, which can be attrib

We present a generalized theory and experimental results of the action signals induced by the absorption of two photons from two phase-modulated laser beams. In our experiment, the phases of the laser beams are modulated at the frequencies φ1 and φ2, respectively. Their collinear combination leads to the modulation of the total intensity at the frequency φ=φ2-φ1. The action signals, such as photol

We discuss whether the enhancement in the diphoton final state at Mgg = 750 GeV, observed recently by the ATLAS and CMS Collaborations could be a neutral pseudoscalar technipion π∼0. We considered two distinct minimal models for the dynamical electroweak symmetry breaking. Here we concentrate only on two-flavor vector-like technicolor model and we assume that the two-photon fusion is a dominant pr

While environmental factors strongly influence plant growth and reproduction, less is known about environmental effects on sexual selection and sexual conflict. In this study on mixed-mating Collinsia heterophylla we investigated whether soil resource environment affected traits associated with sexual conflict. In C. heterophylla a sexual conflict over timing of stigma receptivity occurs. Early st

Healthcare inequality is ubiquitous globally, but the effects are most striking in low-resource settings. In these settings, current methods for the design of medical devices are failing to address specific needs. The associated publications rarely describe how the context was studied at the front-end of design. There is a latent need for a holistic contextual framework for guiding the design deci

This paper estimates the influence that rural-to-urban commuting has on rural employment growth, and whether the strength and spatial reach of this effect depend on commuters' levels of education. A main finding is that rural-to-urban commuting has a robust positive impact on rural employment growth in services and retail. There is no significant difference in how far these effects reach into rura

To make distributed systems resource aware and adaptive, they can be modeled as self-adaptive systems. Such systems have a view of their own state and context, which can be represented by a model that is continuously updated and analyzed at runtime. However, such analyses need to be concise and efficient to allow large models and high adaptation rates. To achieve this, we apply reference attribute

BackgroundCellulase enzymes have been reported to contribute with a significant share of the total costs and greenhouse gas emissions of lignocellulosic ethanol production today. A potential future alternative to purchasing enzymes from an off-site manufacturer is to integrate enzyme and ethanol production, using microorganisms and part of the lignocellulosic material as feedstock for enzymes. Thi

High computational cost is the main obstacle to adapting globally optimal branch-and-bound algorithms to intensity-based registration. Existing techniques to speed up such algorithms use a multiresolution pyramid of images and bounds on the target function among different resolutions for rigidly aligning two images. In this paper, we propose a dual algorithm in which the optimization is done in th

The ionophore salinomycin has attracted attention for its exceptional ability to selectively reduce the proportion of cells with stem-like properties in cancer cell populations of varying origin. Targeting the tumorigenicity of such cells is of interest as they are implicated in recurrence, metastasis, and drug resistance. Structural derivatives of salinomycin are thus sought after, both as tools