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Within the field of cell biology, an essential tool is to deliver molecules to cells to manipulate cell behaviour and function. This enables the study of, for example, how a specific change in a cellular process contributes to a disease state. However, cells have barriers, such as the cell membrane, that need to be overcome for the molecules to have an effect. Current transfection methods, such asWithin the field of cell biology, an essential tool is to deliver molecules to cells to manipulate cell behaviour and function. This enables the study of, for example, how a specific change in a cellular process contributes to a disease state. However, cells have barriers, such as the cell membrane, that need to be overcome for the molecules to have an effect. Current transfection methods, such as

A Finnish national climate research programme, SILMU, has funded three projects in the field of ozone and UV radiation research during 1990-1995. The results of these projects are summarised here. The study of temperature sounding records made in Finland 1958-94 has revealed a warming trend in the lower and middle troposphere (up to 0.3 K/decade) and a cooling of similar order of magnitude in the

Measurements of tropospheric ozone at three sites at the Arctic Circle in the Finnish Lapland are presented. The variability of ground-level ozone over the diurnal and seasonal cycles in 1992-93 is discussed for the sites of Oulanka and Pallas. The variability with height and over the annual cycle in 1989-94 is discussed for the Sodankyla aerological Observatory, which has the longest record on th

Birds periodically replace their flight feathers through moulting, a process needed to restore aerodynamic function that temporarily reduces the wing surface and flight performance. To mitigate these effects, birds adjust their wings, the angle of attack, and undergo mass loss to compensate for altered aerodynamics.Studying the aerodynamic impact of moult gaps in live birds is challenging, so we u

Balloon borne frost-point hygrometers and backscatter sondes were launched at Sodankylä, Finland in January and February of 1996. These instruments measure water vapor and the backscatter ratio of light due to polar stratospheric clouds in the Arctic stratospheric vortex. Here we report the results of a hygrometer sonde and a backscatter sonde launched within 3.5 hours of each other on January 22/

It is well established that extensive depletion of ozone, initiated by heterogenous reactions on polar stratospheric clouds (PSCs) can occur in both the Arctic and Antarctic lower stratosphere. Moreover, it has been shown that ozone loss rates in the Arctic region in recent years reached values comparable to those over the Antarctic. But until now the accumulated ozone losses over the Arctic have

The absence of LIDAR depolarization in a polar cirrus observed above Sodankyla (Finland) showed the presence of spherical particles at -65°C. The presence of pure liquid water is excluded, since homogeneous freezing should occur at or above -40°C. The cirrus layer was detected at the tropopause, during the horizontal and vertical advection above northern Scandinavia of warm and wet oceanic air. Tw

LONG-TERM depletion of ozone has been observed since the early 1980s in the Antarctic polar vortex, and more recently at mid-latitudes in both hemispheres, with most of the ozone loss occurring in the lower stratosphere1. Insufficient measurements of ozone exist, however, to determine decadal trends in ozone concentration in the Arctic winter. Several studies of ozone concentrations in the Arctic

Despite several randomized controlled trials demonstrating the benefits of combination therapies for metastatic hormone-sensitive prostate cancer (mHSPC), a significant treatment gap persists. This initiative by the Prostate Cancer Foundation (PCF) convened stakeholders from academia, community practices, industry, and patient advocacy groups to address critical challenges in mHSPC care. Expert di

Even after fifty years since its introduction, the empirical Thornton’s structure zone diagram remains a valuable tool for predicting thin film microstructure. This diagram is essential for understanding the correlation between synthesis, composition, structure, and physical properties in emerging applications. In this work, we critically appraise this diagram by examining Sn─O thin films grown at

Amid growing geopolitical tensions and the shift toward a multipolar world, research security has emerged as a critical concern for academic institutions and national governments. While efforts to protect science from foreign interference and intellectual property theft are increasing, many current measures lack empirical grounding, clear objectives, or proven effectiveness. This paper discusses t

In daylight, urban forests promote human health and well-being by offering opportunities for recreation and psychological restoration. In urban forests, electric lighting is often installed to enable recreation during the dark season. This study explored how urban residents experience walking in an urban forest in daylight compared to walking in darkness with electric lighting. Local residents par

Diffusion–relaxation correlation multidimensional MRI (MD-MRI) replaces voxel-averaged diffusion tensor quantities and (Formula presented.) and (Formula presented.) relaxation rates with their multidimensional distributions, enabling the selective extraction and mapping of specific diffusion–relaxation spectral ranges that correspond to different cellular features. This approach has the potential

Objective: Classification criteria for early-stage symptomatic knee osteoarthritis (EsSKOA) should discriminate individuals with EsSKOA from those with other causes of knee symptoms. We sought to identify conditions in the differential diagnosis of EsSKOA in adults with knee symptoms. Design: We conducted an online survey of clinicians. Those consulting monthly on at least five people with undiagn

Introduction: Glucagon-like peptide-1 (GLP-1) receptor agonists including Mounjaro and Ozempic, are increasingly used for weight management. Assessing the attitudes and beliefs of current and future healthcare professionals is important considering their roles in recommending and prescribing these drugs. This study aimed to investigate the attitudes toward Mounjaro and Ozempic and its correlation

Being information literate, i.e. being able to critically evaluate information and arguments in relation to empirical evidence, is extremely important. Our study combines learning science and drama to explore if 6th grade students can grasp certain aspects of information literacy, such as fake news and filter bubbles. By analyzing free-text responses we concluded that the students are aware of the

The Swedish Regional Climate Modelling Programme, SWECLIM, was a 6.5-year national research network for regional climate modeling, regional climate change projections and hydrological impact assessment and information to a wide range of stakeholders. Most of the program activities focussed on the regional climate system of Northern Europe. This led to the establishment of an advanced, coupled atmo

Titel: Digitalisering av byggprocessen genom drönarburna avbildningsmetoder: Möjligheter och utmaningar med avbildningsmetoderna LiDAR och fotogrammetri Författare: Melker Hollén, Robin Lundqvist Handledare: Carlos Martinez Examinator: Radhlinah Aulin Syfte & mål: Analysera drönarburen LiDAR-mätning och fotogrammetri-mätning och se hur de bidrar till digitaliseringen av byggbranschen samt

I takt med att Sverige strävar efter att uppnå klimatneutralitet har återvinning av schaktmassor fått ökad betydelse. Vikten av samordning mellan olika bygg- och anläggningsprojekt har lyfts för att öka den cirkulära masshanteringen. Lokalt belägna återvinningsanläggningar för massor har angetts som ett sätt att underlätta återvinningen av massor. Samtidigt upplevs lagstiftningen som reglerar olikThe management of excavated materials is becoming more important as Sweden works towards climate neutrality. Improved coordination between construction projects and the use of local recycling facilities are seen as key to enabling circular mass management. However, the legislation governing the establishment and operation of mass recycling facilities is perceived as unclear, particularly regarding

Shoshana Zuboff means that the world is increasingly defined by a new system of control she calls ‘surveillance capitalism’ – an emerging digital market in the business of mining, selling, modifying and predicting human behavior through digital surveillance. Concerns have been raised that this obfuscated but ubiquitous form of governance is detrimental for individual autonomy. This thesis aims to