Over the last 15 years, treatment of comatose post-cardiac arrest patients has evolved to include therapeutic strategies such as urgent coronary angiography with percutaneous coronary intervention (PCI), targeted temperature management (TTM)—requiring mechanical ventilation and sedation—and more sophisticated and cautious prognostication. In 2015, collaboration between the European Resuscitation C

The immune response against intracerebral grafts of allogeneic fetal dopamine-rich tissue was assessed in adult rats. Sprague-Dawley rats, now outbred, but originating from an inbred stock, were given unilateral 6-hydroxy-dopamine lesions of the mesostriatal pathway, and grafted intrastriatally with mechanically dissociated ventral mesencephalic tissue (embryonic day 13-15) obtained from an inbred

Brain interstitial and cerebrospinal fluid drainage into the lymphatics was studied by injections of 5 microliters of packed sheep red blood cells (SRBC) injected into the caudate nucleus, the occipital lobe, and the lateral ventricle of the brain in mice. The number of plaque-forming cells (PFC) was determined in the deep cervical lymph nodes, the axillary lymph nodes, and the spleen, and the num

Acute leukemia is a worldwide disease with an incidence of approximately 4/100 000 per year; 70% of the cases are acute myeloid leukemia (AML). The salient pathologic feature of AML is the excessive accumulation of immature myeloid blasts in the bone marrow (BM). This maturation arrest, a characteristic of acute leukemias, prevents normal hematopoiesis and leads, directly or indirectly, to a lack

Employing fault tolerance often introduces a time overhead, which may cause a deadline violation in real-time systems (RTS). Therefore, for RTS it is important to optimize the fault tolerance techniques such that the probability to meet the deadlines, i.e. The Level of Confidence (LoC), is maximized. Previous studies have focused on evaluating the LoC for equidistant checkpointing. However, no stu

'If you read only one book on the English language-read this one. English - One Tongue, Many Voices covers all aspects of the English language: its global spread, international and local varieties, history from obscurity to primacy, usage and uses, standards and creoles, style and change in progress, politics and controversy. The scope of the book is vast, its depth impressive, and its balance adm

Background: Protein kinase C o (PKCo) is known to be an important regulator of apoptosis, having mainly pro-but also anti-Apoptotic effects depending on context. In a previous study, we found that PKCo interacts with the pro-Apoptotic protein Smac. Smac facilitates apoptosis by suppressing inhibitor of apoptosis proteins (IAPs). We previously established that the PKCo-Smac complex dissociates duri

The most efficient way of building up energy in an oscillating system is to do it in phase with a resonant frequency of the system. If the resonant frequency changes for any reason this is difficult to obtain with a static frequency generator. It is of course possible to sweep over a frequency interval to find the maximum repeatedly, but a frequency sweep takes time and it is performed at discrete

Background: Data are lacking from general population studies on how to define changes in lung function after bronchodilation. This study aimed to analyze different measures of bronchodilator response of forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and slow vital capacity (SVC). Materials and methods: Data were derived from the Swedish Cardiopulmonary Bioimage Study (SCA

In the design of concrete bridges an important aspect is limiting crack widths, since large cracks can lead to e.g. corrosion and affect the bridge functionality. Restraint forces caused by thermal loads and shrinkage will likely constitute a large part of the total forces acting on the bridge in crack width design. In this paper, restraint stresses in portal frame bridges are calculated according

Svensk Kärnbränslehantering (SKB) har som en av sina uppgifter att skapa kunskap om hur betongen i slutförvaret för kortlivat radioaktivt avfall (SFR) kommer att åldras och hur det i sin tur kommer att påverka betongbarriärens skyddande förmåga. I tre studier har därför avdelningen för Byggnadsmaterial vid Lunds Tekniska Högskola med olika experimentella undersökningar studerat hur betongens egens

We present the development of a specialized concrete for neutron shielding at neutron research facilities, based on the addition of hydrogen atoms in the form of polyethylene and also B4C for enhancing the neutron capture properties of the concrete. We show information on the mechanical properties of the concrete and the neutronics, in particular its relevance to modern spallation neutron sources,

PURPOSE OF REVIEW: Delayed awakening after targeted temperature management (TTM) and sedation is frequent among cardiac arrest patients. Differentiating between prolonged coma and irreversible cerebral damage can be challenging, therefore the utilization of a multimodal approach is recommended by international guidelines. Here, we discuss indications and advantages/disadvantages of available modal

This article presents further biographical information about a little-known composer of mandolin and guitar pieces, the Italian-British musician and music teacher Angelo (Angy) Palumbo (1883–1960).

The pentadentate ligand 14-oxa-1,4,8,11-tetraazabicyclo[9.5.3]nonadecane (L1) has been synthesized by the high dilution cyclization of 1-oxa-4,8-diazacyclododecane ([10]aneN2O) (1) with 1,3-bis(α-chloroacetamido)propane (2) and subsequent reduction of the diamide intermediate. The structure [Ni(L1)(ClO4)](ClO4) (P21/c (no. 14), a = 8.608(3), b = 16.618(3), c = 14.924(4) Å, β = 91.53(3)° converged