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The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct Study

Background: Epidemiologic evidence of an association between fish intake and type 2 diabetes (T2D) is inconsistent and unresolved. Objective: The objective was to examine the association between total and type of fish intake and T2D in 8 European countries. Design: This was a case-cohort study, nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, with 3.99 m

Microscopic studies providing insight into the mechanisms of mass transfer in vacuum impregnation

A microscopic method was developed to detect pressure thresholds for gas outflow and solution impregnation during vacuum impregnation of plant materials. Raw materials with different porosities (apple and spinach) were impregnated with an isotonic sucrose solution at a minimum pressure of 150 mbar. An automatic vacuum controller system (AVCS) was used to control the pressure during vacuum impregna

Determinants of outcome in lumbar spinal stenosis surgery

Lumbar spinal stenosis (LSS) is a degenerative disorder of the spine that predominantly affects the elderly. LSS is the most common spinal disorder leading to surgery in Sweden. Recent randomized controlled studies have showed better outcome with surgery compared to conservative treatment. However, after surgery, health related quality of life (HRQoL) and function continue to be inferior to that o

On the commutant of C(X) in C*-crossed products by Z and their representations

For the C*-crossed product C*(Sigma) associated with an arbitrary topological dynamical system Sigma = (X, sigma), we provide a detailed analysis of the commutant, in C*(Sigma), of C(X) and the commutant of the image of C(X) under an arbitrary Hilbert space representation (pi) over tilde of C*(E), In particular, we give a concrete description of these commutants, and also determine their spectra.

EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis

The objective was to develop evidence -based recommendations and a research and educational agenda for the non-pharmacological management of hip and knee osteoarthritis (OA). The multidisciplinary task force comprised 21 experts: nurses, occupational therapists, physiotherapists, rheumatologists, orthopaedic surgeons, general practitioner, psychologist, dietician, clinical epidemiologist and patie

European Association of Urology Guidelines on Vasectomy

Context: The European Association of Urology presents its guidelines for vasectomy. Vasectomy is highly effective, but problems can arise that are related to insufficient preoperative patient information, the surgical procedure, and postoperative follow-up. Objective: These guidelines aim to provide information and recommendations for physicians who perform vasectomies and to promote the provision

Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion.

Secretagogin is a hexa EF-hand Ca(2+)-binding protein expressed in neuroendocrine, pancreatic endocrine and retinal cells. The protein has been noted for its expression in specific neuronal subtypes in the support of hierarchical organizing principles in the mammalian brain. Secretagogin has previously been found to interact with SNAP25 involved in Ca(2+)-induced exocytosis. Here, the cellular int

Effect of Treatment with Natalizumab on Ability to Work in People with Multiple Sclerosis Productivity Gain Based on Direct Measurement of Work Capacity before and after 1 Year of Treatment

Background: Sweden is a high endemic region for multiple sclerosis (MS), a neurologic disorder characterized by repeated inflammatory episodes affecting the CNS. The disease has its peak age of onset at approximately 30 years and affects women twice as often as men. The young age of onset makes MS one of the major causes of reduced capacity to work due to neurologic disease in Western society. Nat

Gender specific age-related changes in bone density, muscle strength and functional performance in the elderly: a-10 year prospective population-based study

Background: Age-related losses in bone mineral density (BMD), muscle strength, balance, and gait have been linked to an increased risk of falls, fractures and disability, but few prospective studies have compared the timing, rate and pattern of changes in each of these measures in middle-aged and older men and women. This is important so that targeted strategies can be developed to optimise specif

(Z)-3-Dodecenoic acid Is the main component of full-body n-hexane extracts from two Acacia gall-inducing thrips (Thysanoptera) and may function as an alarm pheromone

A major interest in the gall-inducing thrips of Australia began with the discovery that some species have eusocial colonies. The origin of social castes remains one of the outstanding questions in evolutionary biology. The inference of the ancestral stage from study of solitary species is important to understanding the evolutionary history of semiochemicals in social species. Here we investigated

Understanding Drug Uptake and Binding within Targeted Disease Micro-Environments in Patients: A New Tool for Translational Medicine

For many common global diseases, such as cancer, diabetes, neurodegenerative and cardiovascular diseases there is an unmet need for diagnosing early indications of disease that could enable medical intervention and early treatment. For example, cigarette smoking causes a variety of deadly diseases including lung cancer, hypertension, chronic obstructive pulmonary disease (COPD) and cardiovascular

Predictors of default from follow-up care in a cervical cancer screening program using direct visual inspection in south-western Nigeria

Background: Increasingly evidence is emerging from south East Asia, southern and east Africa on the burden of default to follow up care after a positive cervical cancer screening/diagnosis, which impacts negatively on cervical cancer prevention and control. Unfortunately little or no information exists on the subject in the West Africa sub region. This study was designed to determine the proportio