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Lundaloppet predictive challenge 2017

Published 5 May 2017 Photo: Melburnian Guess your time in Lundaloppet 2017 and express your uncertainty in your running time in which way you want! After the race on May 13th and the actual running times are known, we will evaluate the performances of all predictions. The results will be presented in June, where we will hand out several awards.Guess your time in Lundaloppet 2017 and express your u

https://www.cec.lu.se/article/lundaloppet-predictive-challenge-2017 - 2025-01-08

Impact of missing data on bias and precision when estimating change in patient-reported outcomes from a clinical registry

Published 24 September 2019 Clinical registries, which capture information about the health and healthcare use of patients with a health condition or treatment, often contain patient-reported outcomes (PROs) that provide insights about the patient’s perspectives on their health. Missing data can affect the value of PRO data for healthcare decision-making. We compared the precision and bias of seve

https://www.lupop.lu.se/article/impact-missing-data-bias-and-precision-when-estimating-change-patient-reported-outcomes-clinical - 2025-01-08

Registry-Based Medical Research: Data Dredging or Value Building to Quality of Care?

Published 25 September 2019 Registry-based medical research is an important tool in assessing health care interventions in the general population. Observational studies are used to establish effectiveness whereas randomized clinical trials assess efficacy in an experimental manner targeting a carefully selected population of patients. Medical registries may be office or hospital based, state/provi

https://www.lupop.lu.se/article/registry-based-medical-research-data-dredging-or-value-building-quality-care - 2025-01-08

Data verification of nationwide clinical quality registries

Published 26 September 2019 Clinical auditing is an emerging instrument for quality assessment and improvement.Moreover, clinical registries facilitate medical research as they provide ‘real world’ data. It is importantthat entered data are robust and reliable. The aim of this study was to describe the evolving procedureand results of data verication within the Dutch Institute for Clinical Auditi

https://www.lupop.lu.se/article/data-verification-nationwide-clinical-quality-registries - 2025-01-08

Risk and outcome of hepatocellular carcinoma in liver cirrhosis in Southern Sweden: a population-based study

Published 27 September 2019 Liver cirrhosis is a risk factor for hepatocellular carcinoma (HCC). While the HCC risk is thought to be highest in hepatitis B and hepatitis C, the risk in other cirrhosis etiologies is not fully established. Therefore, we aimed to study the risk and outcome of HCC in alcoholic cirrhosis compared to cirrhosis of other etiologies, in Sweden. New publication in Scandinav

https://www.lupop.lu.se/article/risk-and-outcome-hepatocellular-carcinoma-liver-cirrhosis-southern-sweden-population-based-study - 2025-01-08

Contextualizing selection bias in Mendelian randomization: how bad is it likely to be?

Published 30 September 2019 Selection bias affects Mendelian randomization investigations when selection into the study sample depends on a collider between the genetic variant and confounders of the risk factor–outcome association. However, the relative importance of selection bias for Mendelian randomization compared with other potential biases is unclear. New publication in International Journa

https://www.lupop.lu.se/article/contextualizing-selection-bias-mendelian-randomization-how-bad-it-likely-be - 2025-01-08

Barriers and Opportunities for Use of Patient Registries in Medicines Regulation

Published 2 October 2019 The European Medicines Agency (EMA) established the Patient Registry Initiative to explore ways of supporting the use of patient registries in generating high-quality data for regulatory decision making and to enable a systematic approach to their use. We review barriers and opportunities for using patient registries in medicines regulation. A key aspect is that early disc

https://www.lupop.lu.se/article/barriers-and-opportunities-use-patient-registries-medicines-regulation - 2025-01-08

Bayesian Methods for Exposure Misclassification Adjustment in a Mediation Analysis

Published 3 October 2019 Soil-transmitted helminth infections have been found to be associated with child development. The objective was to investigate hemoglobin levels and malnutrition as mediators of the association between Ascaris infection and intelligence quotient (IQ) scores in children. New publication in Epidemiology.Read more here.

https://www.lupop.lu.se/article/bayesian-methods-exposure-misclassification-adjustment-mediation-analysis - 2025-01-08

The what, when and how of orthopaedic registers: an introduction into register-based research

Published 4 October 2019 Establishment of orthopaedic registers started in 1975 and many registers have been initiated since. The main purpose of registers is to collect information on patients, implants and procedures in order to monitor and improve the outcome of the specific procedure. New publicatoin in Efort.Read more here

https://www.lupop.lu.se/article/what-when-and-how-orthopaedic-registers-introduction-register-based-research-0 - 2025-01-08