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ERC grant advances study of B Cells' crucial role in our immune system

By katrin [dot] stahl [at] med [dot] lu [dot] se (Katrin Ståhl and Johan Joelsson) - published 24 November 2023 Joan Yuan received the prestigious ERC Consolidator Grant 2023 for the project: Unraveling the Role of Early Life B Cells in Shaping the Adult Immune System. Joan Yuan, associate professor of immunology at the Department of Laboratory Medicine, and researcher at Lund Stem Cell Center, is

https://www.stemcellcenter.lu.se/article/erc-grant-advances-study-b-cells-crucial-role-our-immune-system - 2025-03-15

Exploring Genomic Dark Matter: Christopher Douse Awarded $1.2M Grant by Chan Zuckerberg Initiative

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 2 January 2024 Christopher Douse explores the repetitive portion of the human genome, so-called ‘genomic dark matter’, and its role in human brain development and degeneration. Photo: Alexis Bento Luis. Christopher Douse, a new group leader at the Faculty of Medicine at Lund University, has been awarded the Ben Barres

https://www.stemcellcenter.lu.se/article/exploring-genomic-dark-matter-christopher-douse-awarded-12m-grant-chan-zuckerberg-initiative - 2025-03-15

From leukemia to lung cancer - funding for regenerative medicine advances cancer research

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 6 February 2024 At the end of 2023, researchers at Lund Stem Cell Center received funding amounting to SEK 77.5 million from the Swedish Research Council, the Swedish Cancer Society, and the Swedish Childhood Cancer Fund. Photo credit: Kenneth Ruona World Cancer Day, celebrated on 04 February, is a time to reflect on t

https://www.stemcellcenter.lu.se/article/leukemia-lung-cancer-funding-regenerative-medicine-advances-cancer-research - 2025-03-15

Intrinsic Aging or Lab-Induced Stress? Understanding Genetic Changes in Blood Stem Cells

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 4 March 2024 Lund University researchers find that individual blood stem cells (depicted as snowflakes in this image) express stress-related transcripts when subjected to experimental procedures involving cell incubation at elevated temperatures. Image // Marcin Minor Changes occur in all cells of the human body as we

https://www.stemcellcenter.lu.se/article/intrinsic-aging-or-lab-induced-stress-understanding-genetic-changes-blood-stem-cells - 2025-03-15

Severe brain trauma activates dormant endogenous retroviruses in the brain

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 14 March 2024 In a study led by Lund University, researchers can show for the first time that traumatic brain injuries activate dormant endogenous retroviruses that have been inserted into human DNA over the course of millions of years. The activation of these viruses may be the driving force behind the inflammation that worse

https://www.stemcellcenter.lu.se/article/severe-brain-trauma-activates-dormant-endogenous-retroviruses-brain - 2025-03-15

The Bridge - Lungs for Life: EU Funding Supports Öresund Lung Transplant Initiative

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 4 April 2024 ‘The Bridge - Lungs for Life’ initiative received EU funding to establish a centralized Danish-Swedish "renovation facility" for damaged lungs – a first-of-its-kind endeavor in Europe. Photo credit: Karl Hörnfeldt // Unsplash Many lung patients face a critical shortage of organs for transplantation. To add

https://www.stemcellcenter.lu.se/article/bridge-lungs-life-eu-funding-supports-oresund-lung-transplant-initiative - 2025-03-15

From Students to Scientists: The never-ending journey of stem cell research begins at UniStem Day 2024

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 15 April 2024 High school students from Skåne, Sweden, learn how to use chicken embryos to study childhood cancer with researchers in the Mohlin lab during UniStem Day 2024. In the heart of Lund, anticipation filled the air as over 230 high school students from across Skåne, Sweden, gathered in a bustling auditorium at

https://www.stemcellcenter.lu.se/article/students-scientists-never-ending-journey-stem-cell-research-begins-unistem-day-2024 - 2025-03-15

Wellbeing and Belonging Promote Success in Academia

By sara [dot] liedholm [at] med [dot] lu [dot] se (Sara Liedholm) - published 23 April 2024 Desiree Dickerson leads the workshop "Connecting Minds: Navigating Isolation and Building Belonging in Academic Life" with a diverse group of researchers, students, and staff from the Lund Stem Cell Center. Isolation is a major problem for many in Academia. To counteract this among researchers and doctoral

https://www.stemcellcenter.lu.se/article/wellbeing-and-belonging-promote-success-academia - 2025-03-15

Drawing the molecular roadmap of Human Natural Killer Cell development

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 29 April 2024 Researchers studying natural killer cells present a comprehensive map of how these cells develop in humans, detailing their regulatory networks along the way. Image credit: AI-illustrated artwork via Midjourney // Dang Nghiem Vo At any given time, more than 2 billion natural killer cells patrol the adult

https://www.stemcellcenter.lu.se/article/drawing-molecular-roadmap-human-natural-killer-cell-development - 2025-03-15

Update on STEM-PD clinical trial – stem cell-based transplant for Parkinson’s disease

By press [at] med [dot] lu [dot] se (Katrin Ståhl) - published 7 May 2024 Photo from stem cell transplantation at Skåne University Hospital. Source: Skåne University Hospital. Higher dose cohort initiated after positive early safety evaluation in Parkinson's therapy. After a positive initial safety evaluation, the pioneering STEM-PD clinical trial has advanced to higher dose testing. STEM-PD is a

https://www.stemcellcenter.lu.se/article/update-stem-pd-clinical-trial-stem-cell-based-transplant-parkinsons-disease - 2025-03-15

Enzymes from intestinal bacteria opens up for universal blood

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 30 May 2024 Researchers at Lund University and the Technical University of Denmark (DTU) in Copenhagen have discovered a new method that takes us one step closer to universal blood. Image: iStock/MusMuculus. Researchers at Lund University and DTU in Copenhagen have discovered enzymes in the colon that, when mixed with red bloo

https://www.stemcellcenter.lu.se/article/enzymes-intestinal-bacteria-opens-universal-blood - 2025-03-15

A New Era of Flow Cytometry Arrives at the FACS Core Facility

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 4 June 2024 Anna Fossum, head of the FACS Core Facility research infrastructure, along with researchers Nicholas Leigh, Chimezie Umeano, and Marlene Johanna Oesterle, collect and analyze data on the new BD FACSDiscover. Photo: Alexis Luis. At Lund University’s Biomedical Centre, the FACS Core Facility hums with activit

https://www.stemcellcenter.lu.se/article/new-era-flow-cytometry-arrives-facs-core-facility - 2025-03-15

How Hidden Genetic Elements Trigger a Rare Neurodegenerative Disorder

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 25 June 2024 Researchers at Lund University have discovered how a hidden piece of DNA, known as a transposable element, disrupts normal gene function in a disease called X-Linked Dystonia-Parkinsonism (XDP). Image // Science Photo Library Researchers at Lund University have discovered how a hidden piece of DNA, known a

https://www.stemcellcenter.lu.se/article/how-hidden-genetic-elements-trigger-rare-disorder - 2025-03-15

Where Science Meets Art: Inside Lund Stem Cell Center's 2024 Image Competition

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 11 July 2024 The Lund Stem Cell Center held its annual image competition from April to May 2024. In June, the 15 image entries were assessed, and the top images were selected according to the evaluators' scores. There comes a point in every researcher's work when the data goes beyond numbers and charts, transforming in

https://www.stemcellcenter.lu.se/article/where-science-meets-art-inside-lund-stem-cell-centers-2024-image-competition - 2025-03-15

Professor Filipe Pereira awarded ERC Proof of Concept Grant

By info [at] med [dot] lu [dot] se (Faculty of Medicine) - published 11 July 2024 By reprogramming tumour cells to become the body’s defenders, Filipe Pereira and his colleagues hope to improve current cancer treatments. Photo by: Johan Persson Filipe Pereira and his research team have discovered a recipe on how to reprogram cancer cells into antigen-presenting dendritic cells, essential for initi

https://www.stemcellcenter.lu.se/article/professor-filipe-pereira-awarded-erc-proof-concept-grant - 2025-03-15

The gene that controls the prognosis in neuroblastoma

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 6 August 2024 Sofie Mohlin's research team has discovered that the MOXD1 gene is associated with neuroblastoma. Every year, about twenty children in Sweden get neuroblastoma. Most of them are diagnosed before the age of five. Some develop the disease in the fetal stage Neuroblastoma is a tumor disease that primarily af

https://www.stemcellcenter.lu.se/article/gene-controls-prognosis-neuroblastoma - 2025-03-15

Digital behandling av knäartros överlägsen traditionell vård

Av olle [dot] dahlback [at] med [dot] lu [dot] se (Olle Dahlbäck) - publicerad 1 mars 2021 Patienter med knäartros som tränar med hjälp av dagliga övningar i en app, når överlägset bättre resultat än de som genomgår traditionell egenvårdsbehandling. Det visar en ny studie som forskare vid University of Nottingham i Storbritannien publicerar i den vetenskapliga tidskriften JAMA Network Open. – Stud

https://www.medicin.lu.se/artikel/digital-behandling-av-knaartros-overlagsen-traditionell-vard - 2025-03-15

Aktivering av gamla virus orsakar inflammation senare i livet

Av alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - publicerad 3 mars 2021 En förstorad bild av en nervcell (blå) som förlorat den epigenetiska kontrollen av ERV och därmed uttrycker virusrelaterade protein (röd). Foto: Marie Jönsson Forskare vid Stamcellscentrum, Lunds universitet, lyfter fram vikten av att kontrollera virala beståndsdelar som finns i arvsmassan och hur deras

https://www.medicin.lu.se/artikel/aktivering-av-gamla-virus-orsakar-inflammation-senare-i-livet - 2025-03-15

Nya kliniska kännetecken vid aggressiv bröstcancer

Av asa [dot] hansdotter [at] med [dot] lu [dot] se (Alexander Doyle och Åsa Hansdotter) - publicerad 4 mars 2021 Bilden föreställer bröstcancerceller som uttrycker en stamcellsmarkör (i grönt) och ett tätt sammanvuxet mitokondrielt nätverk (i rött). Foto: Maciej Ciesla Forskare från Lunds universitet har upptäckt en ny mekanism där cancerceller kapar metabolismen hos ribonukleinsyra (RNA) för att

https://www.medicin.lu.se/artikel/nya-kliniska-kannetecken-vid-aggressiv-brostcancer - 2025-03-15

Migrän-pionjär får världens största pris inom hjärnforskning

Av olle [dot] dahlback [at] med [dot] lu [dot] se (Olle Dahlbäck) - publicerad 4 mars 2021 Professor Lars Edvinsson vid Institutionen för kliniska vetenskaper i Lund får det prestigefyllda "The Brain Prize" för sin framgångsrika forskning om migrän. Foto: Tove Smeds I början av 1970-talet klev Lars Edvinsson för första gången in genom dörrarna på Lunds universitet. Då som nyantagen läkarstudent oc

https://www.medicin.lu.se/artikel/migran-pionjar-far-varldens-storsta-pris-inom-hjarnforskning - 2025-03-15